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Protein

Uncharacterized protein US12

Gene

US12

Organism
Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein US12
Gene namesi
Name:US12
OrganismiHuman cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
Taxonomic identifieri295027 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeBetaherpesvirinaeCytomegalovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000000938 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei58 – 78HelicalSequence analysisAdd BLAST21
Transmembranei88 – 107HelicalSequence analysisAdd BLAST20
Transmembranei117 – 137HelicalSequence analysisAdd BLAST21
Transmembranei145 – 165HelicalSequence analysisAdd BLAST21
Transmembranei171 – 191HelicalSequence analysisAdd BLAST21
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Transmembranei248 – 268HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Host membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004182931 – 281Uncharacterized protein US12Add BLAST281

Proteomic databases

PRIDEiF5HE44

Structurei

3D structure databases

SMRiF5HE44
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytomegalovirus US12 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiVOG090000JG

Family and domain databases

InterProiView protein in InterPro
IPR006214 Bax_inhibitor_1-related
PfamiView protein in Pfam
PF01027 Bax1-I, 1 hit

Sequencei

Sequence statusi: Complete.

F5HE44-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVQIQFHQGE PLGHKKEKPP PVSPPSPPPI RRVTVITKDE DTLRSVQHFL
60 70 80 90 100
WMVRLYGTVV FQTSATIATT ILFMLIPWRV TTPYLRDTLP FWSTLLPCAL
110 120 130 140 150
RCHAYWLERQ RRPGTLMLVM VYTTLTTISV STIGLCFDRT VVIQAYVLSS
160 170 180 190 200
MLCVWCTGLA WLMAWNMQRR LAILCLLSFM LPILWLFIAV QSWEPYQRII
210 220 230 240 250
LALTVSFIYG LKIVLIRDTL TVLYRSPSNC YTDGDLLRTA MLLYMDQVIM
260 270 280
FLLVVVPLTA PIWYPNYAGA LGRTAHWLFH K
Length:281
Mass (Da):32,471
Last modified:June 28, 2011 - v1
Checksum:i22F7CD9FD7F4B70F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY446894 Genomic DNA Translation: AAR31701.1
RefSeqiYP_081597.1, NC_006273.2

Genome annotation databases

GeneIDi3077562
KEGGivg:3077562

Similar proteinsi

Entry informationi

Entry nameiUS12_HCMVM
AccessioniPrimary (citable) accession number: F5HE44
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2012
Last sequence update: June 28, 2011
Last modified: May 23, 2018
This is version 16 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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