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Protein
Submitted name:

COP9 signalosome complex subunit 7a

Gene

COPS7A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
COP9 signalosome complex subunit 7aImported
Gene namesi
Name:COPS7AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000111652.9
HGNCiHGNC:16758 COPS7A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000111652

PTM / Processingi

Proteomic databases

MaxQBiF5H7C6
PeptideAtlasiF5H7C6
PRIDEiF5H7C6

Expressioni

Gene expression databases

BgeeiENSG00000111652 Expressed in 232 organ(s), highest expression level in anterior cingulate cortex
ExpressionAtlasiF5H7C6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5H7C6
SMRiF5H7C6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 159PCIInterPro annotationAdd BLAST159

Phylogenomic databases

eggNOGiKOG3250 Eukaryota
ENOG410XP7W LUCA
GeneTreeiENSGT00390000013069

Family and domain databases

InterProiView protein in InterPro
IPR037757 COPS7A
IPR000717 PCI_dom
PANTHERiPTHR15350:SF7 PTHR15350:SF7, 1 hit
PfamiView protein in Pfam
PF01399 PCI, 1 hit
SMARTiView protein in SMART
SM00088 PINT, 1 hit
PROSITEiView protein in PROSITE
PS50250 PCI, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

F5H7C6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAEVKVTGQ NQEQFLLLAK SAKGAALATL IHQVLEAPGV YVFGELLDMP
60 70 80 90 100
NVRELAESDF ASTFRLLTVF AYGTYADYLA EARNLPPLTE AQKNKLRHLS
110 120 130 140 150
VVTLAAKVKC IPYAVLLEAL ALRNVRQLED LVIEAVYADV LRGSLDQRNQ
160 170 180 190
RLEVDYSIGR DIQRQDLSAI ARTLQEWCVG CEVVLSGIEE QV
Length:192
Mass (Da):21,307
Last modified:June 28, 2011 - v1
Checksum:iF7C4817B819EB5A2
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9UBW8CSN7A_HUMAN
COP9 signalosome complex subunit 7a
COPS7A CSN7A, DERP10
275Annotation score:
F5H248F5H248_HUMAN
COP9 signalosome complex subunit 7a
COPS7A
262Annotation score:
F5GYF7F5GYF7_HUMAN
COP9 signalosome complex subunit 7a
COPS7A
212Annotation score:
F5H4U8F5H4U8_HUMAN
COP9 signalosome complex subunit 7a
COPS7A
125Annotation score:
F5H3M6F5H3M6_HUMAN
COP9 signalosome complex subunit 7a
COPS7A
60Annotation score:
F5H4Z0F5H4Z0_HUMAN
COP9 signalosome complex subunit 7a
COPS7A
56Annotation score:
F5GXT7F5GXT7_HUMAN
COP9 signalosome complex subunit 7a
COPS7A
71Annotation score:
G3XAP1G3XAP1_HUMAN
COP9 constitutive photomorphogenic ...
COPS7A hCG_25925
62Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei192Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125494 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000541866; ENSP00000442613; ENSG00000111652
UCSCiuc058kjz.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC125494 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF5H7C6
SMRiF5H7C6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF5H7C6
PeptideAtlasiF5H7C6
PRIDEiF5H7C6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000541866; ENSP00000442613; ENSG00000111652
UCSCiuc058kjz.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000111652.9
HGNCiHGNC:16758 COPS7A
OpenTargetsiENSG00000111652
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3250 Eukaryota
ENOG410XP7W LUCA
GeneTreeiENSGT00390000013069

Miscellaneous databases

ChiTaRSiCOPS7A human

Gene expression databases

BgeeiENSG00000111652 Expressed in 232 organ(s), highest expression level in anterior cingulate cortex
ExpressionAtlasiF5H7C6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR037757 COPS7A
IPR000717 PCI_dom
PANTHERiPTHR15350:SF7 PTHR15350:SF7, 1 hit
PfamiView protein in Pfam
PF01399 PCI, 1 hit
SMARTiView protein in SMART
SM00088 PINT, 1 hit
PROSITEiView protein in PROSITE
PS50250 PCI, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF5H7C6_HUMAN
AccessioniPrimary (citable) accession number: F5H7C6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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