UniProtKB - F5H7C6 (F5H7C6_HUMAN)
Protein
Submitted name:
COP9 signalosome complex subunit 7a
Gene
COPS7A
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: COP9 signalosome complex subunit 7aImported |
Gene namesi | Name:COPS7AImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:16758, COPS7A |
VEuPathDBi | HostDB:ENSG00000111652.9 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Nucleus
- COP9 signalosome Source: InterPro
- nucleoplasm Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000111652, Expressed in prefrontal cortex and 245 other tissues |
ExpressionAtlasi | F5H7C6, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 159 | PCIInterPro annotationAdd BLAST | 159 |
Sequence similaritiesi
Phylogenomic databases
GeneTreei | ENSGT00940000159873 |
HOGENOMi | CLU_054426_1_0_1 |
Family and domain databases
InterProi | View protein in InterPro IPR037757, COPS7A IPR041481, CSN7_helixI IPR000717, PCI_dom |
PANTHERi | PTHR15350:SF7, PTHR15350:SF7, 1 hit |
Pfami | View protein in Pfam PF18392, CSN7a_helixI, 1 hit PF01399, PCI, 1 hit |
SMARTi | View protein in SMART SM00088, PINT, 1 hit |
PROSITEi | View protein in PROSITE PS50250, PCI, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All
F5H7C6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSAEVKVTGQ NQEQFLLLAK SAKGAALATL IHQVLEAPGV YVFGELLDMP
60 70 80 90 100
NVRELAESDF ASTFRLLTVF AYGTYADYLA EARNLPPLTE AQKNKLRHLS
110 120 130 140 150
VVTLAAKVKC IPYAVLLEAL ALRNVRQLED LVIEAVYADV LRGSLDQRNQ
160 170 180 190
RLEVDYSIGR DIQRQDLSAI ARTLQEWCVG CEVVLSGIEE QV
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UBW8 | CSN7A_HUMAN | COP9 signalosome complex subunit 7a | COPS7A CSN7A, DERP10 | 275 | Annotation score: | ||
F5H248 | F5H248_HUMAN | COP9 signalosome complex subunit 7a | COPS7A | 262 | Annotation score: | ||
F5GYF7 | F5GYF7_HUMAN | COP9 signalosome complex subunit 7a | COPS7A | 212 | Annotation score: | ||
F5H4U8 | F5H4U8_HUMAN | COP9 signalosome complex subunit 7a | COPS7A | 125 | Annotation score: | ||
G3XAP1 | G3XAP1_HUMAN | COP9 constitutive photomorphogenic ... | COPS7A hCG_25925 | 62 | Annotation score: | ||
F5GXT7 | F5GXT7_HUMAN | COP9 signalosome complex subunit 7a | COPS7A | 71 | Annotation score: | ||
F5H3M6 | F5H3M6_HUMAN | COP9 signalosome complex subunit 7a | COPS7A | 60 | Annotation score: | ||
F5H4Z0 | F5H4Z0_HUMAN | COP9 signalosome complex subunit 7a | COPS7A | 56 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 192 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC125494 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000541866; ENSP00000442613; ENSG00000111652 |
UCSCi | uc058kjz.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC125494 Genomic DNA No translation available. |
3D structure databases
SMRi | F5H7C6 |
ModBasei | Search... |
Proteomic databases
MaxQBi | F5H7C6 |
PeptideAtlasi | F5H7C6 |
ProteomicsDBi | 27448 |
Protocols and materials databases
Antibodypediai | 11091, 206 antibodies |
Genome annotation databases
Ensembli | ENST00000541866; ENSP00000442613; ENSG00000111652 |
UCSCi | uc058kjz.1, human |
Organism-specific databases
HGNCi | HGNC:16758, COPS7A |
OpenTargetsi | ENSG00000111652 |
VEuPathDBi | HostDB:ENSG00000111652.9 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000159873 |
HOGENOMi | CLU_054426_1_0_1 |
Miscellaneous databases
ChiTaRSi | COPS7A, human |
Gene expression databases
Bgeei | ENSG00000111652, Expressed in prefrontal cortex and 245 other tissues |
ExpressionAtlasi | F5H7C6, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR037757, COPS7A IPR041481, CSN7_helixI IPR000717, PCI_dom |
PANTHERi | PTHR15350:SF7, PTHR15350:SF7, 1 hit |
Pfami | View protein in Pfam PF18392, CSN7a_helixI, 1 hit PF01399, PCI, 1 hit |
SMARTi | View protein in SMART SM00088, PINT, 1 hit |
PROSITEi | View protein in PROSITE PS50250, PCI, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F5H7C6_HUMAN | |
Accessioni | F5H7C6Primary (citable) accession number: F5H7C6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 28, 2011 |
Last sequence update: | June 28, 2011 | |
Last modified: | February 10, 2021 | |
This is version 59 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |