UniProtKB - F5H6C2 (F5H6C2_HUMAN)
Protein
Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY
Gene
IFT88
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- transferase activity Source: UniProtKB-KW
GO - Biological processi
- gibberellic acid mediated signaling pathway Source: UniProtKB-KW
Keywordsi
Molecular function | TransferaseARBA annotation |
Biological process | Gibberellin signaling pathwayARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLYARBA annotation |
Gene namesi | Name:IFT88Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:20606, IFT88 |
VEuPathDBi | HostDB:ENSG00000032742.17 |
Expressioni
Gene expression databases
Bgeei | ENSG00000032742, Expressed in testis and 229 other tissues |
ExpressionAtlasi | F5H6C2, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 35 – 104 | TPR_REGIONInterPro annotationAdd BLAST | 70 | |
Repeati | 71 – 104 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Domaini | 219 – 368 | TPR_REGIONInterPro annotationAdd BLAST | 150 | |
Repeati | 254 – 287 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Repeati | 288 – 321 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Repeati | 322 – 355 | TPRPROSITE-ProRule annotationAdd BLAST | 34 |
Keywords - Domaini
TPR repeatPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00390000015473 |
HOGENOMi | CLU_010738_0_0_1 |
Family and domain databases
Gene3Di | 1.25.40.10, 2 hits |
InterProi | View protein in InterPro IPR006597, Sel1-like IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR001440, TPR_1 IPR019734, TPR_repeat |
Pfami | View protein in Pfam PF00515, TPR_1, 1 hit |
SMARTi | View protein in SMART SM00671, SEL1, 3 hits SM00028, TPR, 6 hits |
SUPFAMi | SSF48452, SSF48452, 2 hits |
PROSITEi | View protein in PROSITE PS50005, TPR, 4 hits PS50293, TPR_REGION, 2 hits |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
F5H6C2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XALEKAKDAG RKERVLVRQR EQVTTPENIN LDLTYSVLFN LASQYSVNEM
60 70 80 90 100
YAEALNTYQV IVKNKMFSNA GILKMNMGNI YLKQRNYSKA IKFYRMALDQ
110 120 130 140 150
VPSVNKQMRI KIMQNIGVTF IQADREKMKK AFQKLITVPL EIDEDKYISP
160 170 180 190 200
SDDPHTNLVT EAIKNDHLRQ MERERKAMAE KYIMTSAKLI APVIETSFAA
210 220 230 240 250
GYDWCVEVVK ASQYVELAND LEINKAVTYL RQKDYNQAVE ILKVLEKKDS
260 270 280 290 300
RVKSAAATNL SALYYMGKDF AQASSYADIA VNSDRYNPAA LTNKGNTVFA
310 320 330 340 350
NGDYEKAAEF YKEALRNDSS CTEALYNIGL TYEKLNRLDE ALDCFLKLHA
360
ILRNSAEVLY QIANMYLI
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ13099 | IFT88_HUMAN | Intraflagellar transport protein 88... | IFT88 TG737, TTC10 | 824 | Annotation score: | ||
F6SRW8 | F6SRW8_HUMAN | Intraflagellar transport protein 88... | IFT88 | 50 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL161772 Genomic DNA No translation available. AL590096 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000537103; ENSP00000437719; ENSG00000032742 |
UCSCi | uc058vue.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL161772 Genomic DNA No translation available. AL590096 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Protein-protein interaction databases
IntActi | F5H6C2, 11 interactors |
Proteomic databases
PeptideAtlasi | F5H6C2 |
PRIDEi | F5H6C2 |
ProteomicsDBi | 27142 |
Protocols and materials databases
Antibodypediai | 22319, 243 antibodies |
Genome annotation databases
Ensembli | ENST00000537103; ENSP00000437719; ENSG00000032742 |
UCSCi | uc058vue.1, human |
Organism-specific databases
HGNCi | HGNC:20606, IFT88 |
OpenTargetsi | ENSG00000032742 |
VEuPathDBi | HostDB:ENSG00000032742.17 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00390000015473 |
HOGENOMi | CLU_010738_0_0_1 |
Miscellaneous databases
ChiTaRSi | IFT88, human |
Gene expression databases
Bgeei | ENSG00000032742, Expressed in testis and 229 other tissues |
ExpressionAtlasi | F5H6C2, baseline and differential |
Family and domain databases
Gene3Di | 1.25.40.10, 2 hits |
InterProi | View protein in InterPro IPR006597, Sel1-like IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR001440, TPR_1 IPR019734, TPR_repeat |
Pfami | View protein in Pfam PF00515, TPR_1, 1 hit |
SMARTi | View protein in SMART SM00671, SEL1, 3 hits SM00028, TPR, 6 hits |
SUPFAMi | SSF48452, SSF48452, 2 hits |
PROSITEi | View protein in PROSITE PS50005, TPR, 4 hits PS50293, TPR_REGION, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F5H6C2_HUMAN | |
Accessioni | F5H6C2Primary (citable) accession number: F5H6C2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 28, 2011 |
Last sequence update: | October 29, 2014 | |
Last modified: | February 10, 2021 | |
This is version 65 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |