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Protein
Submitted name:

Folate receptor beta

Gene

FOLR2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Folate receptor betaImported
Gene namesi
Name:FOLR2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000165457.13
HGNCiHGNC:3793 FOLR2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000165457

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_500332759422 – 171Sequence analysisAdd BLAST150

Proteomic databases

PeptideAtlasiF5H4Z6
PRIDEiF5H4Z6

Expressioni

Gene expression databases

BgeeiENSG00000165457 Expressed in 215 organ(s), highest expression level in esophagus
ExpressionAtlasiF5H4Z6 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5H4Z6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 171Folate_recInterPro annotationAdd BLAST142

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IFFP Eukaryota
ENOG4111IU4 LUCA
GeneTreeiENSGT00390000010470

Family and domain databases

InterProiView protein in InterPro
IPR004269 Folate_rcpt
IPR018143 Folate_rcpt-like
IPR032937 FOLR2
PANTHERiPTHR10517 PTHR10517, 1 hit
PTHR10517:SF8 PTHR10517:SF8, 1 hit
PfamiView protein in Pfam
PF03024 Folate_rec, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

F5H4Z6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVWKWMPLLL LLVCVATMCS AQDRTDLLNV CMDAKHHKTK PGPEDKLHDQ
60 70 80 90 100
CSPWKKNACC TASTSQELHK DTSRLYNFNW DHCGKMEPAC KRHFIQDTCL
110 120 130 140 150
YECSPNLGPW IQQVNQSWRK ERFLDVPLCK EDCQRWWEDC HTSHTCKSNW
160 170
HRGWDWTSGV NKCPAGALCR T
Length:171
Mass (Da):20,027
Last modified:June 28, 2011 - v1
Checksum:iF4BE9529287F62E0
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P14207FOLR2_HUMAN
Folate receptor beta
FOLR2
255Annotation score:
J3KQP4J3KQP4_HUMAN
Folate receptor beta
FOLR2
251Annotation score:
F5H3Z4F5H3Z4_HUMAN
Folate receptor beta
FOLR2
198Annotation score:
E7EU04E7EU04_HUMAN
Folate receptor beta
FOLR2
210Annotation score:
F5GZ45F5GZ45_HUMAN
Folate receptor beta
FOLR2
180Annotation score:
A0A087WWY2A0A087WWY2_HUMAN
Folate receptor beta
FOLR2
244Annotation score:
F5GXV3F5GXV3_HUMAN
Folate receptor beta
FOLR2
169Annotation score:
J3KR13J3KR13_HUMAN
Folate receptor beta
FOLR2
214Annotation score:
F5H5L8F5H5L8_HUMAN
Folate receptor beta
FOLR2
148Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei171Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000593 Genomic DNA No translation available.
KF455414 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000535625; ENSP00000444794; ENSG00000165457
UCSCiuc058fae.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000593 Genomic DNA No translation available.
KF455414 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF5H4Z6
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiF5H4Z6
PRIDEiF5H4Z6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000535625; ENSP00000444794; ENSG00000165457
UCSCiuc058fae.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000165457.13
HGNCiHGNC:3793 FOLR2
OpenTargetsiENSG00000165457
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IFFP Eukaryota
ENOG4111IU4 LUCA
GeneTreeiENSGT00390000010470

Miscellaneous databases

ChiTaRSiFOLR2 human

Gene expression databases

BgeeiENSG00000165457 Expressed in 215 organ(s), highest expression level in esophagus
ExpressionAtlasiF5H4Z6 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR004269 Folate_rcpt
IPR018143 Folate_rcpt-like
IPR032937 FOLR2
PANTHERiPTHR10517 PTHR10517, 1 hit
PTHR10517:SF8 PTHR10517:SF8, 1 hit
PfamiView protein in Pfam
PF03024 Folate_rec, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF5H4Z6_HUMAN
AccessioniPrimary (citable) accession number: F5H4Z6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 12, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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