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Protein
Submitted name:

Lysine-specific demethylase 2B

Gene

KDM2B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Lysine-specific demethylase 2BImported
Gene namesi
Name:KDM2BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000089094.16
HGNCiHGNC:13610 KDM2B

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000089094

PTM / Processingi

Proteomic databases

MaxQBiF5H4A7
PeptideAtlasiF5H4A7
PRIDEiF5H4A7

Expressioni

Gene expression databases

BgeeiENSG00000089094 Expressed in 196 organ(s), highest expression level in female gonad
ExpressionAtlasiF5H4A7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5H4A7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 115JmjCInterPro annotationAdd BLAST115

Phylogenomic databases

eggNOGiKOG1633 Eukaryota
KOG1947 Eukaryota
ENOG410XQXU LUCA
GeneTreeiENSGT00550000074396

Family and domain databases

InterProiView protein in InterPro
IPR003347 JmjC_dom
PfamiView protein in Pfam
PF02373 JmjC, 1 hit
SMARTiView protein in SMART
SM00558 JmjC, 1 hit
PROSITEiView protein in PROSITE
PS51184 JMJC, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All

F5H4A7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVKGCFTDF HIDFGGTSVW YHVFRGGKIF WLIPPTLHNL ALYEEWVLSG
60 70 80 90 100
KQSDIFLGDR VERCQRIELK QGYTFFIPSG WIHAVYTPVD SLVFGGNILH
110 120 130 140 150
SFNVPMQLRI YEIEDRTRVQ PKFRYPFYYE MCWYVLERYV YCVTQRSHLT
160 170
QEYQRESMLI DAPRKPSIDG F
Length:171
Mass (Da):20,372
Last modified:June 28, 2011 - v1
Checksum:i173D18004B8FEC6A
GO

Computationally mapped potential isoform sequencesi

There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8NHM5KDM2B_HUMAN
Lysine-specific demethylase 2B
KDM2B CXXC2, FBL10, FBXL10, JHDM1B, PCCX2
1,336Annotation score:
F6SRV7F6SRV7_HUMAN
Lysine-specific demethylase 2B
KDM2B
706Annotation score:
A0A0C4DGG3A0A0C4DGG3_HUMAN
Lysine-specific demethylase 2B
KDM2B
704Annotation score:
F5H6N6F5H6N6_HUMAN
Lysine-specific demethylase 2B
KDM2B
154Annotation score:
F5GXW2F5GXW2_HUMAN
Lysine-specific demethylase 2B
KDM2B
123Annotation score:
F8WBN2F8WBN2_HUMAN
Lysine-specific demethylase 2B
KDM2B
510Annotation score:
F5GXC2F5GXC2_HUMAN
Lysine-specific demethylase 2B
KDM2B
180Annotation score:
F5H7T7F5H7T7_HUMAN
Lysine-specific demethylase 2B
KDM2B
97Annotation score:
F5H4X4F5H4X4_HUMAN
Lysine-specific demethylase 2B
KDM2B
125Annotation score:
S4R3G4S4R3G4_HUMAN
Lysine-specific demethylase 2B
KDM2B
507Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei171Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC048337 Genomic DNA No translation available.
AC073650 Genomic DNA No translation available.
AC145422 Genomic DNA No translation available.
KC877509 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000538379; ENSP00000445102; ENSG00000089094
UCSCiuc058uhy.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC048337 Genomic DNA No translation available.
AC073650 Genomic DNA No translation available.
AC145422 Genomic DNA No translation available.
KC877509 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF5H4A7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF5H4A7
PeptideAtlasiF5H4A7
PRIDEiF5H4A7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000538379; ENSP00000445102; ENSG00000089094
UCSCiuc058uhy.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000089094.16
HGNCiHGNC:13610 KDM2B
OpenTargetsiENSG00000089094
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1633 Eukaryota
KOG1947 Eukaryota
ENOG410XQXU LUCA
GeneTreeiENSGT00550000074396

Miscellaneous databases

ChiTaRSiKDM2B human

Gene expression databases

BgeeiENSG00000089094 Expressed in 196 organ(s), highest expression level in female gonad
ExpressionAtlasiF5H4A7 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR003347 JmjC_dom
PfamiView protein in Pfam
PF02373 JmjC, 1 hit
SMARTiView protein in SMART
SM00558 JmjC, 1 hit
PROSITEiView protein in PROSITE
PS51184 JMJC, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF5H4A7_HUMAN
AccessioniPrimary (citable) accession number: F5H4A7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 12, 2018
This is version 42 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health

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