Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - F5H269 (F5H269_HUMAN)

Entry version 79 (02 Dec 2020)
Sequence version 1 (28 Jun 2011)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

DmX-like protein 1

Gene

DMXL1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		F5H269

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DmX-like protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DMXL1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000172869.14

Human Gene Nomenclature Database

More...HGNCi		HGNC:2937, DMXL1

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000172869

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		F5H269

MaxQB - The MaxQuant DataBase

More...MaxQBi		F5H269

PeptideAtlas

More...PeptideAtlasi		F5H269

PRoteomics IDEntifications database

More...PRIDEi		F5H269

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		25877

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000172869, Expressed in pigmented layer of retina and 242 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		F5H269, baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2903 – 2986WD_REPEATS_REGIONInterPro annotationAdd BLAST84
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati2945 – 2986WDPROSITE-ProRule annotationAdd BLAST42

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni420 – 450DisorderedSequence analysisAdd BLAST31
Regioni563 – 584DisorderedSequence analysisAdd BLAST22
Regioni2367 – 2412DisorderedSequence analysisAdd BLAST46
Regioni2446 – 2468DisorderedSequence analysisAdd BLAST23

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2454 – 2468AcidicSequence analysisAdd BLAST15

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

WD repeatPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00390000000096

Identification of Orthologs from Complete Genome Data

More...OMAi		LRDWHQS

Database of Orthologous Groups

More...OrthoDBi		127808at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		F5H269

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.130.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR022033, Rav1p_C
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12234, Rav1p_C, 1 hit
PF00400, WD40, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00320, WD40, 10 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50978, SSF50978, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

F5H269-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNLHQVLTGA VNPGDHCFSV GSIGDQRFTA YASGCDIVIL GSDFERLQII 
        60         70         80         90        100
PGAKHGNIQV GCVDCSMQQG KIAASYGNVI SIFEPVNLPK QKKNLELYSQ 
       110        120        130        140        150
WQKSGQFFLE SIAHNITWDP TGSRLLTGSS YLQLWSNTNL EKPTEDENLN 
       160        170        180        190        200
KTDLNFGDWK CIWHCKTASQ VHLMKFSPDG EFFATAGKDD CLLKVWYNVE 
       210        220        230        240        250
NWRTAVTSPD GSSEKQSQGE IDFSFVYLAH PRAVNGFSWR KTSKYMPRAS 
       260        270        280        290        300
VCNVLLTCCK DNVCRLWVET FLPNDCLLYG GDCSHWTESI NLTNNFKRNA 
       310        320        330        340        350
SSKERVQNAL EVNLRHFRRG RRRSLALVAH TGYLPHQQDP HHVHRNTPLH 
       360        370        380        390        400
ANALCHFHIA ASINPATDIP LLPSITSLSL NENEEKTGPF VVHWLNNKEL 
       410        420        430        440        450
HFTLSMEVFL QQLRKSFEQP SSEASVEDSN QADVKSDEET DDGVDDLKIN 
       460        470        480        490        500
PEKKELGCDK MVPNSSFTSL SSAAIDHQIE VLLSEWSKNA DMLFSIHPMD 
       510        520        530        540        550
GSLLVWHVDW LDEYQPGMFR QVQVSFVSRI PVAFPTGDAN SLCKSIMMYA 
       560        570        580        590        600
CTKNVDLAIQ QGKQKPSGLT RSTSMLISSG HNKSSNSLKL SIFTPNVMMI 
       610        620        630        640        650
SKHADGSLNQ WLVSFAEESA FSTVLSISHK SRYCGHRFHL NDLACHSVLP 
       660        670        680        690        700
LLLTTSHHNA LRTPDVDNPE QPFDALNIEE CSLTQQNKST VDVAFQDPSA 
       710        720        730        740        750
VYSELILWRV DPVGPLSFSG GVSELARINS LHVSAFSNVA WLPTLIPSYC 
       760        770        780        790        800
LGAYCNSPSA CFVASDGQYL RLYEAVIDAK KLLSELSNPE ISKYVGEVFN 
       810        820        830        840        850
IVSQQSTARP GCIIALDPIT KLHGRKTQLL HVFEEDFILN NLEKKSLGKD 
       860        870        880        890        900
SILSNAGSSP NGFSEKFYLI VIECTQDNRS LLHMWNLHLK SIPVSLDEKV 
       910        920        930        940        950
DTKLSEAVWQ PEEHYSSSPE KILSPFSQKY QACRANLQST SRLTLFSEMV 
       960        970        980        990       1000
YSQELHLPEG VEIISIKPSA GHLSSSSIYP ACSAPYLLAT SCSDEKVRFW 
      1010       1020       1030       1040       1050
RCRVTDGESA TSKNGKIDLA YIWEEWPLLI EDGLQSNSSI TVPGRPVEVS 
      1060       1070       1080       1090       1100
CAHTNRLAVA YKQPASNSRS SQDFVMHVSI FECESTGGSC WVLEQTIHLD 
      1110       1120       1130       1140       1150
ELSTVLDSGI SVDSNLVAYN KQDMYLSSKE NITSNTKHLV HLDWMSREDG 
      1160       1170       1180       1190       1200
SHILTVGIGS KLFMYGPLAG KVQDQTGKET LAFPLWESTK VVPLSKFVLL 
      1210       1220       1230       1240       1250
RSVDLVSSVD GSPPFPVSLS WVRDGILVVG MDCEMHVYCQ WQPSSKQEPV 
      1260       1270       1280       1290       1300
ITDSYSGSTP SITSLIKQSN SSSGLHPPKK TLTRSMTSLA QKICGKKTAF 
      1310       1320       1330       1340       1350
DPSVDMEDSG LFEAAHVLSP TLPQYHPLQL LELMDLGKVR RAKAILSHLV 
      1360       1370       1380       1390       1400
KCIAGEVVAL NEAESNHERR LRSLTISASG STTRDPQAFN KAENTDYTEI 
      1410       1420       1430       1440       1450
DSVPPLPLYA LLAADDDSCY SSLEKSSNES TLSKSNQLSK ESYDELFQTQ 
      1460       1470       1480       1490       1500
LLMTDTHMLE TDEENTKPRV IDLSQYSPTY FGPEHAQVLS GHLLHSSLPG 
      1510       1520       1530       1540       1550
LSRMEQMSLM ALADTIATTS TDIGESRDRS QGGETLDECG LKFLLAVRLH 
      1560       1570       1580       1590       1600
TFLTTSLPAY RAQLLHQGLS TSHFAWAFHS VAEEELLNML PAMQKDDPTW 
      1610       1620       1630       1640       1650
SELRAMGVGW WVRNTRILRK CIEKVAKAAF YRKNDPLDAA IFYLAMKKKA 
      1660       1670       1680       1690       1700
VIWGLYRAEK NTRMTQFFGH NFEDERWRKA ALKNAFSLLG KQRFEHSAAF 
      1710       1720       1730       1740       1750
FLLAGCLRDA IEVCLEKLND IQLALVIARL YESEFDTSAA YKSILRKKVL 
      1760       1770       1780       1790       1800
GIDSPVSELC SLNINMHHDP FLRSMAYWIL EDYSGALETL IKQPIRENDD 
      1810       1820       1830       1840       1850
QVLSASNPTV FNFYNYLRTH PLLLRRHFGS SDTFSTHMSL TGKSGLAGTI 
      1860       1870       1880       1890       1900
NLSERRLFFT TASAHLKAGC PMLALEVLSK MPKVIKKTRP FYRASSFLDT 
      1910       1920       1930       1940       1950
SKDCSPSSPL KLDAREDKSS AVDWSQSLIN GFGSSSEGSS EKQSNSTLSF 
      1960       1970       1980       1990       2000
DWSQPSVVFQ DDSLELKWDS DNDEENEDVP ISMKELKPLQ RKTDKKLDDI 
      2010       2020       2030       2040       2050
SSNYTESFST LDENDLLNPS EDIIAVQLKF RACLKILTVE LRTLSTGYEI 
      2060       2070       2080       2090       2100
DGGKLRYQLY HWLEKEVIAL QRTCDFCSDA EELQSAFGRN EDEFGLNEDA 
      2110       2120       2130       2140       2150
EDLPHQTKVK QLRENFQEKR QWLLKYQSLL RMFLSYCILH GSHGGGLASV 
      2160       2170       2180       2190       2200
RMELILLLQE SQQETSEPLF SSPLSEQTSV PLLFACTANA KTVVANPLLH 
      2210       2220       2230       2240       2250
LSNLTHDILH AIINFDSPPH PDIQSNKVYV MHTLAASLSA CIYQCLCGSH 
      2260       2270       2280       2290       2300
NYSSFQTNQF TGMVYQTVLL PHRPSLKTGS LDEALTPNTS PAQWPGITCL 
      2310       2320       2330       2340       2350
IRLLNSSGEE AQSGLTVLLC EILTAVYLSL FIHGLATHSS NELFRIVAHP 
      2360       2370       2380       2390       2400
LNEKMWSAVF GGGAHVPSKE QTHSKTLPVS SLVEEGEKQN KRFRPSKMSC 
      2410       2420       2430       2440       2450
RESAPLTPSS APVSQESLAV KEKFIPPELS IWDYFIAKPF LPSSQSRAEY 
      2460       2470       2480       2490       2500
DSEESLGSDD DDNDDDDDVL ASDFHLQEHS NSNSYSWSLM RLAMVQLVLN 
      2510       2520       2530       2540       2550
NLKTFYPFAG HDLAELPVSS PLCHAVLKTL QCWEQVLLRR LEIHGGPPQN 
      2560       2570       2580       2590       2600
YIASHTAEES LSAGPAILRH KALLEPTNTP FKSKHHLALS VKRLWQYLVK 
      2610       2620       2630       2640       2650
QEEIQETFIK NIFTKKRCLN ESLEDNSETI KNSMMEEPNI NKIEADLGYP 
      2660       2670       2680       2690       2700
GGKARIIHKE SDIITAFAVN KANRNCIAIA SSHDVQELDV SGILATQVYT 
      2710       2720       2730       2740       2750
WVDDDIEVET KGSEDFLVIH ARDDLTAVQG TTPYTHSNPG TPINMPWLGS 
      2760       2770       2780       2790       2800
TQTGRGASVM IKKAINNVRR MTSHPTLPYY LTGAQDGSVR MFEWGHSQQI 
      2810       2820       2830       2840       2850
TCFRSGGNSR VTRMRFNYQG NKFGIVDADG YLSLYQTNWK CCPVTGSMPK 
      2860       2870       2880       2890       2900
PYLTWQCHNK TANDFVFVSS SSLIATAGLS TDNRNVCLWD TLVAPANSLV 
      2910       2920       2930       2940       2950
HAFTCHDSGA TVLAYAPKHQ LLISGGRKGF TYVFDLCQRQ QRQLFQSHDS 
      2960       2970       2980       2990       3000
PVKAVAVDPT EEYFVTGSAE GNIKIWSLST FGLLHTFVSE HARQSIFRNI 
      3010       3020       3030       3040 
GTGVMQIETG PANHIFSCGA DGTMKMRILP DQFSPLNEVL KNDVKFML
Length:3,048
Mass (Da):340,244
Last modified:June 28, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2D624F3BCA2C873F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9Y485DMXL1_HUMAN
DmX-like protein 1
DMXL1 XL1
3,027Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EMZ0E7EMZ0_HUMAN
DmX-like protein 1
DMXL1
589Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC008629 Genomic DNA No translation available.
AC027320 Genomic DNA No translation available.
AC118465 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		NP_001277250.1, NM_001290321.2
XP_016864630.1, XM_017009141.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000539542; ENSP00000439479; ENSG00000172869

Database of genes from NCBI RefSeq genomes

More...GeneIDi		1657

UCSC genome browser

More...UCSCi		uc010jcl.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008629 Genomic DNA No translation available.
AC027320 Genomic DNA No translation available.
AC118465 Genomic DNA No translation available.
RefSeqiNP_001277250.1, NM_001290321.2
XP_016864630.1, XM_017009141.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

EPDiF5H269
MaxQBiF5H269
PeptideAtlasiF5H269
PRIDEiF5H269
ProteomicsDBi25877

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		49471, 21 antibodies

Genome annotation databases

EnsembliENST00000539542; ENSP00000439479; ENSG00000172869
GeneIDi1657
UCSCiuc010jcl.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		1657
EuPathDBiHostDB:ENSG00000172869.14
HGNCiHGNC:2937, DMXL1
OpenTargetsiENSG00000172869

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT00390000000096
OMAiLRDWHQS
OrthoDBi127808at2759
PhylomeDBiF5H269

Enzyme and pathway databases

SignaLinkiF5H269

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		1657, 25 hits in 843 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		DMXL1, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		1657

Gene expression databases

BgeeiENSG00000172869, Expressed in pigmented layer of retina and 242 other tissues
ExpressionAtlasiF5H269, baseline and differential

Family and domain databases

Gene3Di2.130.10.10, 3 hits
InterProiView protein in InterPro
IPR022033, Rav1p_C
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
PfamiView protein in Pfam
PF12234, Rav1p_C, 1 hit
PF00400, WD40, 2 hits
SMARTiView protein in SMART
SM00320, WD40, 10 hits
SUPFAMiSSF50978, SSF50978, 2 hits
PROSITEiView protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF5H269_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F5H269
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: December 2, 2020
This is version 79 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again