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Protein
Submitted name:

Fatty acid desaturase 1

Gene

FADS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Fatty acid desaturase 1Imported
Gene namesi
Name:FADS1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000149485.16
HGNCiHGNC:3574 FADS1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei39 – 58HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000149485

PTM / Processingi

Proteomic databases

MaxQBiF5H1Q7
PeptideAtlasiF5H1Q7
PRIDEiF5H1Q7

Expressioni

Gene expression databases

BgeeiENSG00000149485 Expressed in 232 organ(s), highest expression level in mammalian vulva
ExpressionAtlasiF5H1Q7 baseline and differential

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4232 Eukaryota
ENOG410XVSZ LUCA
GeneTreeiENSGT00510000046574

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 16 potential isoforms that are computationally mapped.Show allAlign All

F5H1Q7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNSLLIGELS PEQPSFEPTK NKELTDEFRE LRATVERMGL MKANHVFFLL
60 70 80
YLLHILLLDG AAWLTLWVFG TSFLPFLLCA VLLSAV
Length:86
Mass (Da):9,782
Last modified:June 28, 2011 - v1
Checksum:i427C6B5A1BEC1FA4
GO

Computationally mapped potential isoform sequencesi

There are 16 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O60427FADS1_HUMAN
Fatty acid desaturase 1
FADS1 FADSD5
444Annotation score:
A0A0A0MR51A0A0A0MR51_HUMAN
Fatty acid desaturase 1
FADS1 hCG_40849
501Annotation score:
F5H3U5F5H3U5_HUMAN
Fatty acid desaturase 1
FADS1
192Annotation score:
C9JJB3C9JJB3_HUMAN
Fatty acid desaturase 1
FADS1
139Annotation score:
F5GWE3F5GWE3_HUMAN
Fatty acid desaturase 1
FADS1
165Annotation score:
F5H3P6F5H3P6_HUMAN
Fatty acid desaturase 1
FADS1
146Annotation score:
F5H852F5H852_HUMAN
Fatty acid desaturase 1
FADS1
164Annotation score:
F5GYH4F5GYH4_HUMAN
Fatty acid desaturase 1
FADS1
153Annotation score:
H7C2V0H7C2V0_HUMAN
Fatty acid desaturase 1
FADS1
228Annotation score:
H0YB97H0YB97_HUMAN
Fatty acid desaturase 1
FADS1
175Annotation score:
There are more potential isoformsShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei86Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002380 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000539419; ENSP00000438997; ENSG00000149485
UCSCiuc058cez.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP002380 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF5H1Q7
PeptideAtlasiF5H1Q7
PRIDEiF5H1Q7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000539419; ENSP00000438997; ENSG00000149485
UCSCiuc058cez.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000149485.16
HGNCiHGNC:3574 FADS1
OpenTargetsiENSG00000149485
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG4232 Eukaryota
ENOG410XVSZ LUCA
GeneTreeiENSGT00510000046574

Miscellaneous databases

ChiTaRSiFADS1 human

Gene expression databases

BgeeiENSG00000149485 Expressed in 232 organ(s), highest expression level in mammalian vulva
ExpressionAtlasiF5H1Q7 baseline and differential

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiF5H1Q7_HUMAN
AccessioniPrimary (citable) accession number: F5H1Q7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 12, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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