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Protein
Submitted name:

Centrosomal protein of 57 kDa

Gene

CEP57

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Centrosomal protein of 57 kDaImported
Gene namesi
Name:CEP57Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000166037.10
HGNCiHGNC:30794 CEP57

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166037

PTM / Processingi

Proteomic databases

MaxQBiF5H1B0
PeptideAtlasiF5H1B0
PRIDEiF5H1B0

Expressioni

Gene expression databases

BgeeiENSG00000166037 Expressed in 229 organ(s), highest expression level in intestine
ExpressionAtlasiF5H1B0 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliF5H1B0
SMRiF5H1B0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 205Cep57_CLDInterPro annotationAdd BLAST165

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili39 – 73Sequence analysisAdd BLAST35
Coiled coili81 – 133Sequence analysisAdd BLAST53
Coiled coili155 – 203Sequence analysisAdd BLAST49

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IESE Eukaryota
ENOG410XPJC LUCA
GeneTreeiENSGT00530000063695

Family and domain databases

InterProiView protein in InterPro
IPR010597 Centrosomal_protein_57kDa
IPR025913 Cep57_CLD
PANTHERiPTHR19336:SF11 PTHR19336:SF11, 1 hit
PfamiView protein in Pfam
PF14073 Cep57_CLD, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

F5H1B0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVRHSSSPYV VYPSDKPFLN SDLRRSPSKP TLAYPESNSR AIFSALKNLQ
60 70 80 90 100
DKIRRLELER IQAEESVKTL SRETIEYKKV LDEQIQEREN SKNEESKHNQ
110 120 130 140 150
ELTSQLLAAE NKCNLLEKQL EYMRNMIKHA EMERTSVLEK QVSLERERQH
160 170 180 190 200
DQTHVQSQLE KLDLLEQEYN KLTTMQALAE KKMQELEAKL HEEEQERKRM

QAKAA
Length:205
Mass (Da):24,238
Last modified:June 28, 2011 - v1
Checksum:iC7949860018ABB4B
GO

Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q86XR8CEP57_HUMAN
Centrosomal protein of 57 kDa
CEP57 KIAA0092, TSP57
500Annotation score:
F5GYW0F5GYW0_HUMAN
Centrosomal protein of 57 kDa
CEP57
473Annotation score:
H0YFT8H0YFT8_HUMAN
Centrosomal protein of 57 kDa
CEP57
254Annotation score:
F5H0C6F5H0C6_HUMAN
Centrosomal protein of 57 kDa
CEP57
198Annotation score:
H0YGT4H0YGT4_HUMAN
Centrosomal protein of 57 kDa
CEP57
134Annotation score:
F5GXS6F5GXS6_HUMAN
Centrosomal protein of 57 kDa
CEP57
71Annotation score:
F5H6R3F5H6R3_HUMAN
Centrosomal protein of 57 kDa
CEP57
82Annotation score:
F5H7J4F5H7J4_HUMAN
Centrosomal protein of 57 kDa
CEP57
41Annotation score:
F5GZ93F5GZ93_HUMAN
Centrosomal protein of 57 kDa
CEP57
52Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei205Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001877 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000541365; ENSP00000445821; ENSG00000166037
UCSCiuc058grl.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001877 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF5H1B0
SMRiF5H1B0
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF5H1B0
PeptideAtlasiF5H1B0
PRIDEiF5H1B0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000541365; ENSP00000445821; ENSG00000166037
UCSCiuc058grl.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000166037.10
HGNCiHGNC:30794 CEP57
OpenTargetsiENSG00000166037
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IESE Eukaryota
ENOG410XPJC LUCA
GeneTreeiENSGT00530000063695

Miscellaneous databases

ChiTaRSiCEP57 human

Gene expression databases

BgeeiENSG00000166037 Expressed in 229 organ(s), highest expression level in intestine
ExpressionAtlasiF5H1B0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR010597 Centrosomal_protein_57kDa
IPR025913 Cep57_CLD
PANTHERiPTHR19336:SF11 PTHR19336:SF11, 1 hit
PfamiView protein in Pfam
PF14073 Cep57_CLD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF5H1B0_HUMAN
AccessioniPrimary (citable) accession number: F5H1B0
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 12, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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