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Protein

Peptidylprolyl isomerase

Gene

FKBP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).PROSITE-ProRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionIsomerase, RotamasePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidylprolyl isomerasePROSITE-ProRule annotation (EC:5.2.1.8PROSITE-ProRule annotation)
Gene namesi
Name:FKBP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000173486.12
HGNCiHGNC:3718 FKBP2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000173486

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500332300725 – 102Peptidylprolyl isomeraseSequence analysisAdd BLAST78

Proteomic databases

MaxQBiF5H0N4
PeptideAtlasiF5H0N4
PRIDEiF5H0N4

Expressioni

Gene expression databases

BgeeiENSG00000173486 Expressed in 230 organ(s), highest expression level in pituitary gland
ExpressionAtlasiF5H0N4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5H0N4
SMRiF5H0N4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 102PPIase FKBP-typeInterPro annotationAdd BLAST54

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0549 Eukaryota
COG0545 LUCA
GeneTreeiENSGT00530000062784

Family and domain databases

InterProiView protein in InterPro
IPR023566 PPIase_FKBP
IPR001179 PPIase_FKBP_dom
PANTHERiPTHR10516 PTHR10516, 1 hit
PfamiView protein in Pfam
PF00254 FKBP_C, 1 hit
PROSITEiView protein in PROSITE
PS50059 FKBP_PPIASE, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F5H0N4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRLSWFRVLT VLSICLSAVA TATGAEGKRK LQIGVKKRVD HCPIKSRKGD
60 70 80 90 100
VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE

KR
Length:102
Mass (Da):11,290
Last modified:June 28, 2011 - v1
Checksum:iDF6960DB2FF752E1
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P26885FKBP2_HUMAN
Peptidyl-prolyl cis-trans isomerase...
FKBP2 FKBP13
142Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei102Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001453 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000535135; ENSP00000438749; ENSG00000173486
UCSCiuc058cvo.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001453 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF5H0N4
SMRiF5H0N4
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF5H0N4
PeptideAtlasiF5H0N4
PRIDEiF5H0N4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000535135; ENSP00000438749; ENSG00000173486
UCSCiuc058cvo.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000173486.12
HGNCiHGNC:3718 FKBP2
OpenTargetsiENSG00000173486
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0549 Eukaryota
COG0545 LUCA
GeneTreeiENSGT00530000062784

Miscellaneous databases

ChiTaRSiFKBP2 human

Gene expression databases

BgeeiENSG00000173486 Expressed in 230 organ(s), highest expression level in pituitary gland
ExpressionAtlasiF5H0N4 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR023566 PPIase_FKBP
IPR001179 PPIase_FKBP_dom
PANTHERiPTHR10516 PTHR10516, 1 hit
PfamiView protein in Pfam
PF00254 FKBP_C, 1 hit
PROSITEiView protein in PROSITE
PS50059 FKBP_PPIASE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF5H0N4_HUMAN
AccessioniPrimary (citable) accession number: F5H0N4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: November 7, 2018
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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