UniProtKB - F5GZV7 (F5GZV7_HUMAN)
Protein
Submitted name:
Vesicle-associated membrane protein 1
Gene
VAMP1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Vesicle-associated membrane protein 1Imported |
Gene namesi | Name:VAMP1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000139190.16 |
HGNCi | HGNC:12642, VAMP1 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Single-pass type IV membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 95 – 113 | HelicalSequence analysisAdd BLAST | 19 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000139190, Expressed in primary visual cortex and 225 other tissues |
ExpressionAtlasi | F5GZV7, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 33 – 93 | V-SNARE coiled-coil homologyInterPro annotationAdd BLAST | 61 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 36 | DisorderedSequence analysisAdd BLAST | 36 |
Sequence similaritiesi
Belongs to the synaptobrevin family.ARBA annotation
Keywords - Domaini
Coiled coilPROSITE-ProRule annotationARBA annotation, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000161390 |
Family and domain databases
InterProi | View protein in InterPro IPR001388, Synaptobrevin IPR016444, Synaptobrevin/VAMP IPR042855, V_SNARE_CC |
PANTHERi | PTHR45701, PTHR45701, 1 hit |
Pfami | View protein in Pfam PF00957, Synaptobrevin, 1 hit |
PIRSFi | PIRSF005409, Synaptobrevin_euk, 1 hit |
PRINTSi | PR00219, SYNAPTOBREVN |
PROSITEi | View protein in PROSITE PS00417, SYNAPTOBREVIN, 1 hit PS50892, V_SNARE, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F5GZV7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSAPAQPPAE GTEGTAPGGG PPGPPPNMTS NRRLQQTQAQ VEEVVDIIRV
60 70 80 90 100
NVDKVLERDQ KLSELDDRAD ALQAGASQFE SSAAKLKRKY WWKNCKMMIM
110
LGAICAIIVV VIVRRG
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketP23763 | VAMP1_HUMAN | Vesicle-associated membrane protein... | VAMP1 SYB1 | 118 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005840 Genomic DNA No translation available. |
RefSeqi | NP_001284367.1, NM_001297438.1 |
Genome annotation databases
Ensembli | ENST00000535180; ENSP00000444181; ENSG00000139190 |
GeneIDi | 6843 |
UCSCi | uc058kfc.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC005840 Genomic DNA No translation available. |
RefSeqi | NP_001284367.1, NM_001297438.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | F5GZV7 |
PRIDEi | F5GZV7 |
ProteomicsDBi | 25144 |
Protocols and materials databases
Antibodypediai | 3460, 379 antibodies |
Genome annotation databases
Ensembli | ENST00000535180; ENSP00000444181; ENSG00000139190 |
GeneIDi | 6843 |
UCSCi | uc058kfc.1, human |
Organism-specific databases
CTDi | 6843 |
EuPathDBi | HostDB:ENSG00000139190.16 |
HGNCi | HGNC:12642, VAMP1 |
OpenTargetsi | ENSG00000139190 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000161390 |
Miscellaneous databases
BioGRID-ORCSi | 6843, 2 hits in 846 CRISPR screens |
ChiTaRSi | VAMP1, human |
GenomeRNAii | 6843 |
Gene expression databases
Bgeei | ENSG00000139190, Expressed in primary visual cortex and 225 other tissues |
ExpressionAtlasi | F5GZV7, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR001388, Synaptobrevin IPR016444, Synaptobrevin/VAMP IPR042855, V_SNARE_CC |
PANTHERi | PTHR45701, PTHR45701, 1 hit |
Pfami | View protein in Pfam PF00957, Synaptobrevin, 1 hit |
PIRSFi | PIRSF005409, Synaptobrevin_euk, 1 hit |
PRINTSi | PR00219, SYNAPTOBREVN |
PROSITEi | View protein in PROSITE PS00417, SYNAPTOBREVIN, 1 hit PS50892, V_SNARE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F5GZV7_HUMAN | |
Accessioni | F5GZV7Primary (citable) accession number: F5GZV7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 28, 2011 |
Last sequence update: | June 28, 2011 | |
Last modified: | December 2, 2020 | |
This is version 63 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |