UniProtKB - F5GZP6 (F5GZP6_HUMAN)
Protein
Submitted name:
Liprin-beta-1
Gene
PPFIBP1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Liprin-beta-1Imported |
Gene namesi | Name:PPFIBP1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:9249, PPFIBP1 |
VEuPathDBi | HostDB:ENSG00000110841.13 |
PTM / Processingi
Proteomic databases
MaxQBi | F5GZP6 |
PeptideAtlasi | F5GZP6 |
PRIDEi | F5GZP6 |
ProteomicsDBi | 25092 |
Expressioni
Gene expression databases
Bgeei | ENSG00000110841, Expressed in epithelium of mammary gland and 243 other tissues |
ExpressionAtlasi | F5GZP6, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 478 – 542 | SAMInterPro annotationAdd BLAST | 65 | |
Domaini | 550 – 613 | SAMInterPro annotationAdd BLAST | 64 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 251 – 270 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 294 – 465 | DisorderedSequence analysisAdd BLAST | 172 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 4 – 24 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 35 – 55 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 80 – 121 | Sequence analysisAdd BLAST | 42 | |
Coiled coili | 133 – 167 | Sequence analysisAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 303 – 322 | PolyampholyteSequence analysisAdd BLAST | 20 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisARBA annotation, RepeatARBA annotationPhylogenomic databases
GeneTreei | ENSGT00990000203651 |
HOGENOMi | CLU_011689_2_1_1 |
Family and domain databases
CDDi | cd09563, SAM_liprin-beta1_2_repeat1, 1 hit cd09566, SAM_liprin-beta1_2_repeat2, 1 hit cd09569, SAM_liprin-beta1_2_repeat3, 1 hit |
Gene3Di | 1.10.150.50, 3 hits 1.20.5.1160, 2 hits |
InterProi | View protein in InterPro IPR042180, IF_rod_dom_coil1B IPR029515, Liprin IPR037617, Liprin-beta_SAM_rpt_1 IPR037618, Liprin-beta_SAM_rpt_2 IPR037619, Liprin-beta_SAM_rpt_3 IPR030437, PPFIBP1 IPR001660, SAM IPR013761, SAM/pointed_sf |
PANTHERi | PTHR12587, PTHR12587, 1 hit PTHR12587:SF16, PTHR12587:SF16, 1 hit |
Pfami | View protein in Pfam PF00536, SAM_1, 2 hits PF07647, SAM_2, 1 hit |
SMARTi | View protein in SMART SM00454, SAM, 3 hits |
SUPFAMi | SSF47769, SSF47769, 3 hits |
PROSITEi | View protein in PROSITE PS50105, SAM_DOMAIN, 2 hits |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All
F5GZP6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAEISNLKLK LTAVEKDRLD YEDKFRDTEG LIQEINDLRL KVSEMDSERL
60 70 80 90 100
QYEKKLKSTK SLMAKLSSMK IKVGQMQYEK QRMEQKWESL KDELASLKEQ
110 120 130 140 150
LEEKESEVKR LQEKLVCKMK GEGVEIVDRD IEVQKMKKAV ESLMAANEEK
160 170 180 190 200
DRKIEDLRQC LNRYKKMQDT VVLAQGKKGK DGEYEELLNS SSISSLLDAQ
210 220 230 240 250
GFSDLEKSPS PTPVMGSPSC DPFNTSVPEE FHTTILQVSI PSLLPATVSM
260 270 280 290 300
ETSEKSKLTP KPETSFEEND GNIILGATVD TQLCDKLLTS SLQKSSSLGN
310 320 330 340 350
LKKETSDGEK ETIQKTSEDR APAESRPFGT LPPRPPGQDT SMDDNPFGTR
360 370 380 390 400
KVRSSFGRGF FKIKSNKRTA SAPNLAETEK ETAEHLDLAG ASSRPKDSQR
410 420 430 440 450
NSPFQIPPPS PDSKKKSRGI MKLFGKLRRS QSTTFNPDDM SEPEFKRGGT
460 470 480 490 500
RATAGPRLGW SRDLGQSNSD LDMPFAKWTK EQVCNWLMEQ GLGSYLNSGK
510 520 530 540 550
HWIASGQTLL QASQQDLEKE LGIKHSLHRK KLQLALQALG SEEETNHGKL
560 570 580 590 600
DFNWVTRWLD DIGLPQYKTQ FDEGRVDGRM LHYMTVDDLL SLKVVSVLHH
610 620 630 640 650
LSIKRAIQVL RINNFEPNCL RRRPSDENTI APSEVQKWTN HRVMEWLRSV
660 670 680 690 700
DLAEYAPNLR GSGVHGGLMV LEPRFNVETM AQLLNIPPNK TLLRRHLATH
710 720 730 740
FNLLIGAEAQ HQKRDAMELP DYVLLTATAK VKPKKLAFSN FGNL
Computationally mapped potential isoform sequencesi
There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ86W92 | LIPB1_HUMAN | Liprin-beta-1 | PPFIBP1 KIAA1230 | 1,011 | Annotation score: | ||
H0YGH8 | H0YGH8_HUMAN | Liprin-beta-1 | PPFIBP1 | 205 | Annotation score: | ||
F5H495 | F5H495_HUMAN | Liprin-beta-1 | PPFIBP1 | 152 | Annotation score: | ||
A0A0A0MTP2 | A0A0A0MTP2_HUMAN | Liprin-beta-1 | PPFIBP1 | 281 | Annotation score: | ||
A0A087WVX8 | A0A087WVX8_HUMAN | Liprin-beta-1 | PPFIBP1 | 86 | Annotation score: | ||
H0YFE4 | H0YFE4_HUMAN | Liprin-beta-1 | PPFIBP1 | 242 | Annotation score: | ||
F5H0E0 | F5H0E0_HUMAN | Liprin-beta-1 | PPFIBP1 | 109 | Annotation score: | ||
F5H6Q7 | F5H6Q7_HUMAN | Liprin-beta-1 | PPFIBP1 | 86 | Annotation score: | ||
F5H7K5 | F5H7K5_HUMAN | Liprin-beta-1 | PPFIBP1 | 18 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 744 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009509 Genomic DNA No translation available. AC068794 Genomic DNA No translation available. AC087257 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000540114; ENSP00000444304; ENSG00000110841 |
UCSCi | uc058mfp.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009509 Genomic DNA No translation available. AC068794 Genomic DNA No translation available. AC087257 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
MaxQBi | F5GZP6 |
PeptideAtlasi | F5GZP6 |
PRIDEi | F5GZP6 |
ProteomicsDBi | 25092 |
Protocols and materials databases
Antibodypediai | 1098, 155 antibodies |
Genome annotation databases
Ensembli | ENST00000540114; ENSP00000444304; ENSG00000110841 |
UCSCi | uc058mfp.1, human |
Organism-specific databases
HGNCi | HGNC:9249, PPFIBP1 |
OpenTargetsi | ENSG00000110841 |
VEuPathDBi | HostDB:ENSG00000110841.13 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00990000203651 |
HOGENOMi | CLU_011689_2_1_1 |
Miscellaneous databases
ChiTaRSi | PPFIBP1, human |
Gene expression databases
Bgeei | ENSG00000110841, Expressed in epithelium of mammary gland and 243 other tissues |
ExpressionAtlasi | F5GZP6, baseline and differential |
Family and domain databases
CDDi | cd09563, SAM_liprin-beta1_2_repeat1, 1 hit cd09566, SAM_liprin-beta1_2_repeat2, 1 hit cd09569, SAM_liprin-beta1_2_repeat3, 1 hit |
Gene3Di | 1.10.150.50, 3 hits 1.20.5.1160, 2 hits |
InterProi | View protein in InterPro IPR042180, IF_rod_dom_coil1B IPR029515, Liprin IPR037617, Liprin-beta_SAM_rpt_1 IPR037618, Liprin-beta_SAM_rpt_2 IPR037619, Liprin-beta_SAM_rpt_3 IPR030437, PPFIBP1 IPR001660, SAM IPR013761, SAM/pointed_sf |
PANTHERi | PTHR12587, PTHR12587, 1 hit PTHR12587:SF16, PTHR12587:SF16, 1 hit |
Pfami | View protein in Pfam PF00536, SAM_1, 2 hits PF07647, SAM_2, 1 hit |
SMARTi | View protein in SMART SM00454, SAM, 3 hits |
SUPFAMi | SSF47769, SSF47769, 3 hits |
PROSITEi | View protein in PROSITE PS50105, SAM_DOMAIN, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F5GZP6_HUMAN | |
Accessioni | F5GZP6Primary (citable) accession number: F5GZP6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 28, 2011 |
Last sequence update: | June 28, 2011 | |
Last modified: | February 10, 2021 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |