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Protein
Submitted name:

Thiamin pyrophosphokinase 1

Gene

TPK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Thiamin pyrophosphokinase 1Imported
Gene namesi
Name:TPK1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiHostDB:ENSG00000196511.13
HGNCiHGNC:17358 TPK1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000196511

PTM / Processingi

Proteomic databases

EPDiF5GZG6
MaxQBiF5GZG6
PeptideAtlasiF5GZG6
PRIDEiF5GZG6

Expressioni

Gene expression databases

BgeeiENSG00000196511
ExpressionAtlasiF5GZG6 baseline and differential
GenevisibleiF5GZG6 HS

Structurei

3D structure databases

ProteinModelPortaliF5GZG6
SMRiF5GZG6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini119 – 186TPK_B1_bindingInterPro annotationAdd BLAST68

Phylogenomic databases

GeneTreeiENSGT00390000016016

Family and domain databases

CDDicd07995 TPK, 1 hit
Gene3Di3.40.50.10240, 2 hits
InterProiView protein in InterPro
IPR016966 Thiamin_pyrophosphokinase_euk
IPR007373 Thiamin_PyroPKinase_B1-bd
IPR007371 TPK_catalytic
IPR036759 TPK_catalytic_sf
PfamiView protein in Pfam
PF04265 TPK_B1_binding, 1 hit
PF04263 TPK_catalytic, 1 hit
PIRSFiPIRSF031057 Thiamin_pyrophosphokinase, 2 hits
SMARTiView protein in SMART
SM00983 TPK_B1_binding, 1 hit
SUPFAMiSSF63999 SSF63999, 1 hit

Sequencei

Sequence statusi: Complete.

F5GZG6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHAFTPLEP LLSTGNLKYC LVILNQPLDN YFRHLWNKAL LRACADGGAN
60 70 80 90 100
RLYDITEGER ESFLPEFING DFDSIRPEVR EYYATKGCEL ISTPDQDHTD
110 120 130 140 150
FTKCLKMLQK KIEEKDLKGK HRLHVDTGME GDWCGLIPVG QPCMQVTTTG
160 170 180 190
LKWNLTNDVL AFGTLVSTSN TYDGSGVVTV ETDHPLLWTM AIKS
Length:194
Mass (Da):21,886
Last modified:June 28, 2011 - v1
Checksum:iC673F868C40E8948
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004534 Genomic DNA No translation available.
AC004743 Genomic DNA No translation available.
AC004833 Genomic DNA No translation available.
AC004864 Genomic DNA No translation available.
AC005677 Genomic DNA No translation available.
AC074384 Genomic DNA No translation available.
AC243837 Genomic DNA No translation available.
AC245152 Genomic DNA No translation available.
KF458633 Genomic DNA No translation available.
RefSeqiNP_001035947.1, NM_001042482.1
XP_016867468.1, XM_017011979.1
UniGeneiHs.660232

Genome annotation databases

EnsembliENST00000378099; ENSP00000367339; ENSG00000196511
ENST00000643856; ENSP00000494710; ENSG00000285075
GeneIDi27010
UCSCiuc003wer.4 human

Similar proteinsi

Entry informationi

Entry nameiF5GZG6_HUMAN
AccessioniPrimary (citable) accession number: F5GZG6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: June 20, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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