UniProtKB - F5GYX2 (F5GYX2_HUMAN)
Protein
Submitted name:
Ankyrin repeat domain-containing protein 12
Gene
ANKRD12
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Ankyrin repeat domain-containing protein 12Imported |
Gene namesi | Name:ANKRD12Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000101745.15 |
HGNCi | HGNC:29135, ANKRD12 |
PTM / Processingi
Proteomic databases
EPDi | F5GYX2 |
MaxQBi | F5GYX2 |
PeptideAtlasi | F5GYX2 |
PRIDEi | F5GYX2 |
ProteomicsDBi | 24869 |
Expressioni
Gene expression databases
Bgeei | ENSG00000101745, Expressed in calcaneal tendon and 243 other tissues |
ExpressionAtlasi | F5GYX2, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 153 – 266 | ANK_REP_REGIONInterPro annotationAdd BLAST | 114 | |
Repeati | 159 – 191 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 192 – 224 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 225 – 257 | ANKPROSITE-ProRule annotationAdd BLAST | 33 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 98 | DisorderedSequence analysisAdd BLAST | 98 | |
Regioni | 123 – 165 | DisorderedSequence analysisAdd BLAST | 43 | |
Regioni | 276 – 310 | DisorderedSequence analysisAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 21 | PolarSequence analysisAdd BLAST | 21 | |
Compositional biasi | 22 – 94 | PolyampholyteSequence analysisAdd BLAST | 73 | |
Compositional biasi | 123 – 144 | PolarSequence analysisAdd BLAST | 22 | |
Compositional biasi | 145 – 165 | PolyampholyteSequence analysisAdd BLAST | 21 | |
Compositional biasi | 292 – 310 | PolarSequence analysisAdd BLAST | 19 |
Keywords - Domaini
ANK repeatPROSITE-ProRule annotationARBA annotation, RepeatARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000154742 |
HOGENOMi | CLU_028245_0_0_1 |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 3 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 3 hits |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All
F5GYX2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPKSGFTKPI QSENSDSDSN MVEKPYGRKS KDKIASYSKT PKIERSDVSK
60 70 80 90 100
EMKEKSSMKR KLPFTISPSR NEERDSDTEK EGPEKKKTKK EAGNKKSTPV
110 120 130 140 150
SILFGYPLSE RKQMALLMQM TARDNNSTPN HPSQTTPAQK KTPSSSSRQK
160 170 180 190 200
DKVNKRNERG ETPLHMAAIR GDVKQVKELI SLGANVNVKD FAGWTPLHEA
210 220 230 240 250
CNVGYYDVAK ILIAAGADVN TQGLDDDTPL HDSASSGHRD IVKLLLRHGG
260 270 280 290 300
NPFQANKHGE RPVDVAETEE LELLLKREVP LSDDDESYTD SEEAQSVNPS
310
SVDENIDSET
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ6UB98 | ANR12_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD12 ANCO2, KIAA0874 | 2,062 | Annotation score: | ||
J3KSU9 | J3KSU9_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD12 | 82 | Annotation score: | ||
J3QRX3 | J3QRX3_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD12 | 44 | Annotation score: | ||
B5MEA4 | B5MEA4_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD12 | 97 | Annotation score: | ||
J3KS53 | J3KS53_HUMAN | Ankyrin repeat domain-containing pr... | ANKRD12 | 12 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 310 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP001033 Genomic DNA No translation available. AP005263 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000546007; ENSP00000441510; ENSG00000101745 |
UCSCi | uc060nft.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP001033 Genomic DNA No translation available. AP005263 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
EPDi | F5GYX2 |
MaxQBi | F5GYX2 |
PeptideAtlasi | F5GYX2 |
PRIDEi | F5GYX2 |
ProteomicsDBi | 24869 |
Protocols and materials databases
Antibodypediai | 6510, 59 antibodies |
Genome annotation databases
Ensembli | ENST00000546007; ENSP00000441510; ENSG00000101745 |
UCSCi | uc060nft.1, human |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000101745.15 |
HGNCi | HGNC:29135, ANKRD12 |
OpenTargetsi | ENSG00000101745 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000154742 |
HOGENOMi | CLU_028245_0_0_1 |
Miscellaneous databases
ChiTaRSi | ANKRD12, human |
Gene expression databases
Bgeei | ENSG00000101745, Expressed in calcaneal tendon and 243 other tissues |
ExpressionAtlasi | F5GYX2, baseline and differential |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf |
Pfami | View protein in Pfam PF00023, Ank, 1 hit PF12796, Ank_2, 1 hit |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 3 hits |
SUPFAMi | SSF48403, SSF48403, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F5GYX2_HUMAN | |
Accessioni | F5GYX2Primary (citable) accession number: F5GYX2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 28, 2011 |
Last sequence update: | October 3, 2012 | |
Last modified: | August 12, 2020 | |
This is version 60 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |