UniProtKB - F5GY10 (F5GY10_HUMAN)
Protein
Submitted name:
Transcription factor 12
Gene
TCF12
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Transcription factor 12Imported |
Gene namesi | Name:TCF12Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000140262.17 |
HGNCi | HGNC:11623, TCF12 |
PTM / Processingi
Proteomic databases
EPDi | F5GY10 |
MaxQBi | F5GY10 |
PeptideAtlasi | F5GY10 |
PRIDEi | F5GY10 |
ProteomicsDBi | 24589 |
Expressioni
Gene expression databases
Bgeei | ENSG00000140262, Expressed in corpus callosum and 245 other tissues |
ExpressionAtlasi | F5GY10, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 431 – 484 | BHLHInterPro annotationAdd BLAST | 54 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 79 – 143 | DisorderedSequence analysisAdd BLAST | 65 | |
Regioni | 179 – 222 | DisorderedSequence analysisAdd BLAST | 44 | |
Regioni | 322 – 434 | DisorderedSequence analysisAdd BLAST | 113 | |
Regioni | 505 – 536 | DisorderedSequence analysisAdd BLAST | 32 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 79 – 101 | PolarSequence analysisAdd BLAST | 23 | |
Compositional biasi | 111 – 143 | PolarSequence analysisAdd BLAST | 33 | |
Compositional biasi | 322 – 371 | PolarSequence analysisAdd BLAST | 50 | |
Compositional biasi | 372 – 404 | PolyampholyteSequence analysisAdd BLAST | 33 | |
Compositional biasi | 411 – 434 | PolyampholyteSequence analysisAdd BLAST | 24 | |
Compositional biasi | 522 – 536 | PolarSequence analysisAdd BLAST | 15 |
Phylogenomic databases
GeneTreei | ENSGT00940000155047 |
OrthoDBi | 571132at2759 |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All
F5GY10-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MYCAYPVPGM GSNSLMYYYN GKTVYAPSPN SDDFNRESPS YPSPKPPTSM
60 70 80 90 100
FASTFFMQDG THNSSDLWSS SNGMSQPGFG GILGTSTSHM SQSSSYGNLH
110 120 130 140 150
SHDRLSYPPH SVSPTDINTS LPPMSSFHRG STSSSPYVAA SHTPPINGSD
160 170 180 190 200
SILGTRGNAA GSSQTGDALG KALASIYSPD HTSSSFPSNP STPVGSPSPL
210 220 230 240 250
TGTSQWPRPG GQAPSSPSYE NSLHSLKNRV EQQLHEHLQD AMSFLKDVCE
260 270 280 290 300
QSRMEDRLDR LDDAIHVLRN HAVGPSTSLP AGHSDIHSLL GPSHNAPIGS
310 320 330 340 350
LNSNYGGSSL VASSRSASMV GTHREDSVSL NGNHSVLSST VTTSSTDLNH
360 370 380 390 400
KTQENYRGGL QSQSGTVVTT EIKTENKEKD ENLHEPPSSD DMKSDDESSQ
410 420 430 440 450
KDIKVSSRGR TSSTNEDEDL NPEQKIEREK ERRMANNARE RLRVRDINEA
460 470 480 490 500
FKELGRMCQL HLKSEKPQTK LLILHQAVAV ILSLEQQVRE RNLNPKAACL
510 520 530
KRREEEKVSA VSAEPPTTLP GTHPGLSETT NPMGHM
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ99081 | HTF4_HUMAN | Transcription factor 12 | TCF12 BHLHB20, HEB, HTF4 | 682 | Annotation score: | ||
B4DGI9 | B4DGI9_HUMAN | Transcription factor 12 | TCF12 | 666 | Annotation score: | ||
H0YNQ5 | H0YNQ5_HUMAN | Transcription factor 12 | TCF12 | 157 | Annotation score: | ||
H0YNP8 | H0YNP8_HUMAN | Transcription factor 12 | TCF12 | 339 | Annotation score: | ||
B4DZP2 | B4DZP2_HUMAN | Transcription factor 12 | TCF12 | 316 | Annotation score: | ||
H3BNF4 | H3BNF4_HUMAN | Transcription factor 12 | TCF12 | 48 | Annotation score: | ||
H3BRK2 | H3BRK2_HUMAN | Transcription factor 12 | TCF12 | 44 | Annotation score: | ||
H0YML2 | H0YML2_HUMAN | Transcription factor 12 | TCF12 | 58 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC010999 Genomic DNA No translation available. AC016525 Genomic DNA No translation available. AC090511 Genomic DNA No translation available. AC090532 Genomic DNA No translation available. KF456057 Genomic DNA No translation available. |
RefSeqi | NP_001293148.1, NM_001306219.2 |
Genome annotation databases
Ensembli | ENST00000543579; ENSP00000440017; ENSG00000140262 |
GeneIDi | 6938 |
UCSCi | uc010bft.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC010999 Genomic DNA No translation available. AC016525 Genomic DNA No translation available. AC090511 Genomic DNA No translation available. AC090532 Genomic DNA No translation available. KF456057 Genomic DNA No translation available. |
RefSeqi | NP_001293148.1, NM_001306219.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
EPDi | F5GY10 |
MaxQBi | F5GY10 |
PeptideAtlasi | F5GY10 |
PRIDEi | F5GY10 |
ProteomicsDBi | 24589 |
Protocols and materials databases
Antibodypediai | 913, 372 antibodies |
Genome annotation databases
Ensembli | ENST00000543579; ENSP00000440017; ENSG00000140262 |
GeneIDi | 6938 |
UCSCi | uc010bft.4, human |
Organism-specific databases
CTDi | 6938 |
EuPathDBi | HostDB:ENSG00000140262.17 |
HGNCi | HGNC:11623, TCF12 |
OpenTargetsi | ENSG00000140262 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155047 |
OrthoDBi | 571132at2759 |
Miscellaneous databases
BioGRID-ORCSi | 6938, 13 hits in 866 CRISPR screens |
ChiTaRSi | TCF12, human |
GenomeRNAii | 6938 |
Gene expression databases
Bgeei | ENSG00000140262, Expressed in corpus callosum and 245 other tissues |
ExpressionAtlasi | F5GY10, baseline and differential |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F5GY10_HUMAN | |
Accessioni | F5GY10Primary (citable) accession number: F5GY10 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 28, 2011 |
Last sequence update: | June 28, 2011 | |
Last modified: | December 2, 2020 | |
This is version 75 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |