UniProtKB - F5GXZ5 (F5GXZ5_HUMAN)
Protein
Submitted name:
ATP-binding cassette sub-family B member 9
Gene
ABCB9
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ABC-type peptide transporter activity Source: InterPro
- ATP binding Source: InterPro
Keywordsi
Biological process | TransportARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: ATP-binding cassette sub-family B member 9Imported |
Gene namesi | Name:ABCB9Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:50, ABCB9 |
VEuPathDBi | HostDB:ENSG00000150967.17 |
Subcellular locationi
Lysosome
- lysosomal membrane Source: InterPro
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 103 – 125 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000150967, Expressed in right hemisphere of cerebellum and 221 other tissues |
ExpressionAtlasi | F5GXZ5, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 145 | ABC transmembrane type-1InterPro annotationAdd BLAST | 145 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000155431 |
HOGENOMi | CLU_1791238_0_0_1 |
Family and domain databases
Gene3Di | 1.20.1560.10, 1 hit |
InterProi | View protein in InterPro IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR030254, ABCB9 IPR039421, Type_1_exporter |
PANTHERi | PTHR24221, PTHR24221, 1 hit PTHR24221:SF242, PTHR24221:SF242, 1 hit |
Pfami | View protein in Pfam PF00664, ABC_membrane, 1 hit |
SUPFAMi | SSF90123, SSF90123, 1 hit |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All
F5GXZ5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDQFSTAVVI VCLLAIGSSF AAGIRGGIFT LIFARLNIRL RNCLFRSLVS
60 70 80 90 100
QETSFFDENR TGDLISRLTS DTTMVSDLVS QNINVFLRNT VKVTGVVVFM
110 120 130 140
FSLSWQLSLV TFMGFPIIMM VSNIYGKYYK RLSKEVQNAL ARASN
Computationally mapped potential isoform sequencesi
There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9NP78 | ABCB9_HUMAN | ATP-binding cassette sub-family B m... | ABCB9 KIAA1520 | 766 | Annotation score: | ||
Q6P2Q0 | Q6P2Q0_HUMAN | ABCB9 protein | ABCB9 | 769 | Annotation score: | ||
F5H5F9 | F5H5F9_HUMAN | ATP-binding cassette sub-family B m... | ABCB9 | 222 | Annotation score: | ||
F5H5Q0 | F5H5Q0_HUMAN | ATP-binding cassette sub-family B m... | ABCB9 | 115 | Annotation score: | ||
F5GX86 | F5GX86_HUMAN | ATP-binding cassette sub-family B m... | ABCB9 | 182 | Annotation score: | ||
F5H7U2 | F5H7U2_HUMAN | ATP-binding cassette sub-family B m... | ABCB9 | 277 | Annotation score: | ||
F5GYI2 | F5GYI2_HUMAN | ATP-binding cassette sub-family B m... | ABCB9 | 260 | Annotation score: | ||
F5H0G0 | F5H0G0_HUMAN | ATP-binding cassette sub-family B m... | ABCB9 | 272 | Annotation score: | ||
H7C478 | H7C478_HUMAN | ATP-binding cassette sub-family B m... | ABCB9 | 145 | Annotation score: | ||
F5H4Y2 | F5H4Y2_HUMAN | ATP-binding cassette sub-family B m... | ABCB9 | 156 | Annotation score: | ||
There is more potential isoformShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 145 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC026362 Genomic DNA No translation available. AC027290 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000541424; ENSP00000440138; ENSG00000150967 |
UCSCi | uc058upm.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC026362 Genomic DNA No translation available. AC027290 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | F5GXZ5 |
ProteomicsDBi | 24576 |
Protocols and materials databases
Antibodypediai | 31719, 235 antibodies |
Genome annotation databases
Ensembli | ENST00000541424; ENSP00000440138; ENSG00000150967 |
UCSCi | uc058upm.1, human |
Organism-specific databases
HGNCi | HGNC:50, ABCB9 |
OpenTargetsi | ENSG00000150967 |
VEuPathDBi | HostDB:ENSG00000150967.17 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000155431 |
HOGENOMi | CLU_1791238_0_0_1 |
Miscellaneous databases
ChiTaRSi | ABCB9, human |
Gene expression databases
Bgeei | ENSG00000150967, Expressed in right hemisphere of cerebellum and 221 other tissues |
ExpressionAtlasi | F5GXZ5, baseline and differential |
Family and domain databases
Gene3Di | 1.20.1560.10, 1 hit |
InterProi | View protein in InterPro IPR011527, ABC1_TM_dom IPR036640, ABC1_TM_sf IPR030254, ABCB9 IPR039421, Type_1_exporter |
PANTHERi | PTHR24221, PTHR24221, 1 hit PTHR24221:SF242, PTHR24221:SF242, 1 hit |
Pfami | View protein in Pfam PF00664, ABC_membrane, 1 hit |
SUPFAMi | SSF90123, SSF90123, 1 hit |
PROSITEi | View protein in PROSITE PS50929, ABC_TM1F, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F5GXZ5_HUMAN | |
Accessioni | F5GXZ5Primary (citable) accession number: F5GXZ5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 28, 2011 |
Last sequence update: | October 5, 2016 | |
Last modified: | April 7, 2021 | |
This is version 69 of the entry and version 8 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |