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Protein
Submitted name:

Solute carrier family 2, facilitated glucose transporter member 14

Gene

SLC2A14

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 2, facilitated glucose transporter member 14Imported
Gene namesi
Name:SLC2A14Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000173262.11
HGNCiHGNC:18301 SLC2A14

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 27HelicalSequence analysisAdd BLAST21
Transmembranei63 – 85HelicalSequence analysisAdd BLAST23
Transmembranei122 – 143HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000173262

PTM / Processingi

Proteomic databases

PeptideAtlasiF5GXP8

Expressioni

Gene expression databases

BgeeiENSG00000173262 Expressed in 82 organ(s), highest expression level in right testis
ExpressionAtlasiF5GXP8 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5GXP8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 169MFSInterPro annotationAdd BLAST156

Sequence similaritiesi

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG0569 Eukaryota
COG0477 LUCA
GeneTreeiENSGT00760000119022

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR002945 Glc_transpt_3
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR01192 GLUCTRSPORT3
PR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

F5GXP8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDNRQNVTPA LIFAITVATI GSFQFGYNTG VINAPETIIK EFINKTLTDK
60 70 80 90 100
ANAPPSEVLL TNLWSLSVAI FSVGGMIGSF SVGLFVNRFG RRNSMLIVNL
110 120 130 140 150
LAATGGCLMG LCKIAESVEM LILGRLVIGL FCGLCTGFVP MYIGEISPTA
160
LRGAFGTLNQ LGIVIGILV
Length:169
Mass (Da):17,905
Last modified:June 28, 2011 - v1
Checksum:i2D18F6F270893F21
GO

Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8TDB8GTR14_HUMAN
Solute carrier family 2, facilitate...
SLC2A14 GLUT14, GLUT3
520Annotation score:
F5H076F5H076_HUMAN
Solute carrier family 2, facilitate...
SLC2A14
152Annotation score:
F5H5Q3F5H5Q3_HUMAN
Solute carrier family 2, facilitate...
SLC2A14
141Annotation score:
F5H6F6F5H6F6_HUMAN
Solute carrier family 2, facilitate...
SLC2A14
120Annotation score:
F5GXP7F5GXP7_HUMAN
Solute carrier family 2, facilitate...
SLC2A14
141Annotation score:
F5H7N2F5H7N2_HUMAN
Solute carrier family 2, facilitate...
SLC2A14
84Annotation score:
F5H5V7F5H5V7_HUMAN
Solute carrier family 2, facilitate...
SLC2A14
47Annotation score:
F5H3J0F5H3J0_HUMAN
Solute carrier family 2, facilitate...
SLC2A14
22Annotation score:
F5GXT4F5GXT4_HUMAN
Solute carrier family 2, facilitate...
SLC2A14
38Annotation score:
F5H565F5H565_HUMAN
Solute carrier family 2, facilitate...
SLC2A14
13Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei169Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006517 Genomic DNA No translation available.
AC007536 Genomic DNA No translation available.
AC124891 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000546234; ENSP00000440043; ENSG00000173262
UCSCiuc058kue.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006517 Genomic DNA No translation available.
AC007536 Genomic DNA No translation available.
AC124891 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF5GXP8
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiF5GXP8

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000546234; ENSP00000440043; ENSG00000173262
UCSCiuc058kue.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000173262.11
HGNCiHGNC:18301 SLC2A14
OpenTargetsiENSG00000173262
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0569 Eukaryota
COG0477 LUCA
GeneTreeiENSGT00760000119022

Miscellaneous databases

ChiTaRSiSLC2A14 human

Gene expression databases

BgeeiENSG00000173262 Expressed in 82 organ(s), highest expression level in right testis
ExpressionAtlasiF5GXP8 baseline and differential

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR002945 Glc_transpt_3
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR003663 Sugar/inositol_transpt
IPR005829 Sugar_transporter_CS
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
PRINTSiPR01192 GLUCTRSPORT3
PR00171 SUGRTRNSPORT
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit
PS00217 SUGAR_TRANSPORT_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF5GXP8_HUMAN
AccessioniPrimary (citable) accession number: F5GXP8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 12, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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