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Entry version 71 (05 Jun 2019)
Sequence version 2 (03 Oct 2012)
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Protein
Submitted name:

Nucleosome-remodeling factor subunit BPTF

Gene

BPTF

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Nucleosome-remodeling factor subunit BPTFImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BPTFImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:3581 BPTF

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000171634

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
F5GXF5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
F5GXF5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
F5GXF5

PeptideAtlas

More...
PeptideAtlasi
F5GXF5

PRoteomics IDEntifications database

More...
PRIDEi
F5GXF5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000171634 Expressed in 223 organ(s), highest expression level in kidney

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F5GXF5 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini240 – 300DDTInterPro annotationAdd BLAST61
Domaini390 – 437PHD-typeInterPro annotationAdd BLAST48

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 232DisorderedSequence analysisAdd BLAST232
Regioni567 – 711DisorderedSequence analysisAdd BLAST145
Regioni994 – 1094DisorderedSequence analysisAdd BLAST101
Regioni1152 – 1276DisorderedSequence analysisAdd BLAST125
Regioni1308 – 1385DisorderedSequence analysisAdd BLAST78
Regioni1402 – 1474DisorderedSequence analysisAdd BLAST73
Regioni1542 – 1643DisorderedSequence analysisAdd BLAST102
Regioni1910 – 1940DisorderedSequence analysisAdd BLAST31
Regioni2098 – 2117DisorderedSequence analysisAdd BLAST20
Regioni2169 – 2207DisorderedSequence analysisAdd BLAST39
Regioni2283 – 2457DisorderedSequence analysisAdd BLAST175

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili520 – 540Sequence analysisAdd BLAST21
Coiled coili915 – 939Sequence analysisAdd BLAST25
Coiled coili1960 – 1987Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi18 – 35Pro-richSequence analysisAdd BLAST18
Compositional biasi73 – 88Pro-richSequence analysisAdd BLAST16
Compositional biasi129 – 187AcidicSequence analysisAdd BLAST59
Compositional biasi191 – 205PolarSequence analysisAdd BLAST15
Compositional biasi214 – 229PolyampholyteSequence analysisAdd BLAST16
Compositional biasi567 – 626PolyampholyteSequence analysisAdd BLAST60
Compositional biasi627 – 671PolarSequence analysisAdd BLAST45
Compositional biasi1000 – 1043PolyampholyteSequence analysisAdd BLAST44
Compositional biasi1049 – 1090PolyampholyteSequence analysisAdd BLAST42
Compositional biasi1154 – 1175PolarSequence analysisAdd BLAST22
Compositional biasi1181 – 1220PolarSequence analysisAdd BLAST40
Compositional biasi1221 – 1238PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1246 – 1261PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1308 – 1330PolarSequence analysisAdd BLAST23
Compositional biasi1344 – 1380PolarSequence analysisAdd BLAST37
Compositional biasi1422 – 1463PolyampholyteSequence analysisAdd BLAST42
Compositional biasi1545 – 1597PolarSequence analysisAdd BLAST53
Compositional biasi1604 – 1637PolarSequence analysisAdd BLAST34
Compositional biasi2283 – 2343PolarSequence analysisAdd BLAST61
Compositional biasi2350 – 2457PolarSequence analysisAdd BLAST108

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1473 Eukaryota
KOG1632 Eukaryota
COG5076 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154830

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.920.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038028 BPTF
IPR036427 Bromodomain-like_sf
IPR018501 DDT_dom
IPR028942 WHIM1_dom
IPR028941 WHIM2_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger

The PANTHER Classification System

More...
PANTHERi
PTHR45975 PTHR45975, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02791 DDT, 1 hit
PF00628 PHD, 1 hit
PF15612 WHIM1, 1 hit
PF15613 WSD, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00571 DDT, 1 hit
SM00249 PHD, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57903 SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50827 DDT, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All

F5GXF5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRGRRGRPPK QPAAPAAERC APAPPPPPPP PTSGPIGGLR SRHRGSSRGR
60 70 80 90 100
WAAAQAEVAP KTRLSSPRGG SSSRRKPPPP PPAPPSTSAP GRGGRGGGGG
110 120 130 140 150
RTGGGGGGGH LARTTAARRA VNKVVYDDHE SEEEEEEEDM VSEEEEEEDG
160 170 180 190 200
DAEETQDSED DEEDEMEEDD DDSDYPEEME DDDDDASYCT ESSFRSHSTY
210 220 230 240 250
SSTPGRRKPR VHRPRSPILE EKDIPPLEFP KSSEDLMVPN EHIMNVIAIY
260 270 280 290 300
EVLRNFGTVL RLSPFRFEDF CAALVSQEQC TLMAEMHVVL LKAVLREEDT
310 320 330 340 350
SNTTFGPADL KDSVNSTLYF IDGMTWPEVL RVYCESDKEY HHVLPYQEAE
360 370 380 390 400
DYPYGPVENK IKVLQFLVDQ FLTTNIAREE LMSEGVIQYD DHCRVCHKLG
410 420 430 440 450
DLLCCETCSA VYHLECVKPP LEEVPEDEWQ CEVCVAHKVP GVTDCVAEIQ
460 470 480 490 500
KNKPYIRHEP IGYDRSRRKY WFLNRRLIIE EDTENENEKK IWYYSTKVQL
510 520 530 540 550
AELIDCLDKD YWEAELCKIL EEMREEIHRH MDITEDLTNK ARGSNKSFLA
560 570 580 590 600
AANEEILESI RAKKGDIDNV KSPEETEKDK NETENDSKDA EKNREEFEDQ
610 620 630 640 650
SLEKDSDDKT PDDDPEQGKS EEPTEVGDKG NSVSANLGDN TTNATSEETS
660 670 680 690 700
PSEGRSPVGC LSETPDSSNM AEKKVASELP QDVPVGDFKS EKSNGELSES
710 720 730 740 750
PGAGKGASGS TRIITRLRNP DSKLSQLKSQ QVAAAAHEAN KLFKEGKEVL
760 770 780 790 800
VVNSQGEISR LSTKKEVIMK GNINNYFKLG QEGKYRVYHN QYSTNSFALN
810 820 830 840 850
KHQHREDHDK RRHLAHKFCL TPAGEFKWNG SVHGSKVLTI STLRLTITQL
860 870 880 890 900
ENNIPSSFLH PNWASHRANW IKAVQMCSKP REFALALAIL ECAVKPVVML
910 920 930 940 950
PIWRESLGHT RLHRMTSIER EEKEKVKKKE KKQEEEETMQ QATWVKYTFP
960 970 980 990 1000
VKHQVWKQKG EEYRVTGYGG WSWISKTHVY RFVPKLPGNT NVNYRKSLEG
1010 1020 1030 1040 1050
TKNNMDENMD ESDKRKCSRS PKKIKIEPDS EKDEVKGSDA AKGADQNEMD
1060 1070 1080 1090 1100
ISKITEKKDQ DVKELLDSDS DKPCKEEPME VDDDMKTESH VNCQESSQVD
1110 1120 1130 1140 1150
VVNVSEGFHL RTSYKKKTKS SKLDGLLERR IKQFTLEEKQ RLEKIKLEGG
1160 1170 1180 1190 1200
IKGIGKTSTN SSKNLSESPV ITKAKEGCQS DSMRQEQSPN ANNDQPEDLI
1210 1220 1230 1240 1250
QGCSESDSSV LRMSDPSHTT NKLYPKDRVL DDVSIRSPET KCPKQNSIEN
1260 1270 1280 1290 1300
DIEEKVSDLA SRGQEPSKSK TKGNDFFIDD SKLASADDIG TLICKNKKPL
1310 1320 1330 1340 1350
IQEESDTIVS SSKSALHSSV PKSTNDRDAT PLSRAMDFEG KLGCDSESNS
1360 1370 1380 1390 1400
TLENSSDTVS IQDSSEEDMI VQNSNESISE QFRTREQDVE VLEPLKCELV
1410 1420 1430 1440 1450
SGESTGNCED RLPVKGTEAN GKKPSQQKKL EERPVNKCSD QIKLKNTTDK
1460 1470 1480 1490 1500
KNNENRESEK KGQRTSTFQI NGKDNKPKIY LKGECLKEIS ESRVVSGNVE
1510 1520 1530 1540 1550
PKVNNINKII PENDIKSLTV KESAIRPFIN GDVIMEDFNE RNSSETKSHL
1560 1570 1580 1590 1600
LSSSDAEGNY RDSLETLPST KESDSTQTTT PSASCPESNS VNQVEDMEIE
1610 1620 1630 1640 1650
TSEVKKVTSS PITSEEESNL SNDFIDENGL PINKNENVNG ESKRKTVITE
1660 1670 1680 1690 1700
VTTMTSTVAT ESKTVIKVEK GDKQTVVSST ENCAKSTVTT TTTTVTKLST
1710 1720 1730 1740 1750
PSTGGSVDII SVKEQSKTVV TTTVTDSLTT TGGTLVTSMT VSKEYSTRDK
1760 1770 1780 1790 1800
VKLMKFSRPK KTRSGTALPS YRKFVTKSSK KSIFVLPNDD LKKLARKGGI
1810 1820 1830 1840 1850
REVPYFNYNA KPALDIWPYP SPRPTFGITW RYRLQTVKSL AGVSLMLRLL
1860 1870 1880 1890 1900
WASLRWDDMA AKAPPGGGTT RTETSETEIT TTEIIKRRDV GPYGIRSEYC
1910 1920 1930 1940 1950
IRKIICPIGV PETPKETPTP QRKGLRSSAL RPKRPETPKQ TGPVIIETWV
1960 1970 1980 1990 2000
AEEELELWEI RAFAERVEKE KAQAVEQQAK KRLEQQKPTV IATSTTSPTS
2010 2020 2030 2040 2050
STTSTISPAQ KVMVAPISGS VTTGTKMVLT TKVGSPATVT FQQNKNFHQT
2060 2070 2080 2090 2100
FATWVKQGQS NSGVVQVQQK VLGIIPSSTG TSQQTFTSFQ PRTATVTIRP
2110 2120 2130 2140 2150
NTSGSGGTTS NSQVITGPQI RPGMTVIRTP LQQSTLGKAI IRTPVMVQPG
2160 2170 2180 2190 2200
APQQVMTQII RGQPVSTAVS APNTVSSTPG QKSLTSATST SNIQSSASQP
2210 2220 2230 2240 2250
PRPQQGQVKL TMAQLTQLTQ GHGGNQGLTV VIQGQGQTTG QLQLIPQGVT
2260 2270 2280 2290 2300
VLPGPGQQLM QAAMPNGTVQ RFLFTPLATT ATTASTTTTT VSTTAAGTGE
2310 2320 2330 2340 2350
QRQSKLSPQM QVHQDKTLPP AQSSSVGPAE AQPQTAQPSA QPQPQTQPQS
2360 2370 2380 2390 2400
PAQPEVQTQP EVQTQTTVSS HVPSEAQPTH AQSSKPQVAA QSQPQSNVQG
2410 2420 2430 2440 2450
QSPVRVQSPS QTRIRPSTPS QLSPGQQSQV QTTTSQPIPI QPHTSLQIPS

QGQPQSQ
Length:2,457
Mass (Da):271,531
Last modified:October 3, 2012 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9F79C4F757FFE7D2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q12830BPTF_HUMAN
Nucleosome-remodeling factor subuni...
BPTF FAC1, FALZ
3,046Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7ETD6E7ETD6_HUMAN
Nucleosome-remodeling factor subuni...
BPTF
2,764Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MR81A0A0A0MR81_HUMAN
Nucleosome-remodeling factor subuni...
BPTF
810Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PE19E9PE19_HUMAN
Nucleosome-remodeling factor subuni...
BPTF
2,822Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QQK4J3QQK4_HUMAN
Nucleosome-remodeling factor subuni...
BPTF
339Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Y7Q1A0A2R8Y7Q1_HUMAN
Nucleosome-remodeling factor subuni...
BPTF
2,965Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3KSK9J3KSK9_HUMAN
Nucleosome-remodeling factor subuni...
BPTF
484Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QQQ8J3QQQ8_HUMAN
Nucleosome-remodeling factor subuni...
BPTF
420Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F5H176F5H176_HUMAN
Nucleosome-remodeling factor subuni...
BPTF
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3QLW4J3QLW4_HUMAN
Nucleosome-remodeling factor subuni...
BPTF
69Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There is more potential isoformShow all

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei2457Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC006534 Genomic DNA No translation available.
AC107377 Genomic DNA No translation available.
AC134407 Genomic DNA No translation available.
KC877674 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000544778; ENSP00000440854; ENSG00000171634

UCSC genome browser

More...
UCSCi
uc010wqm.2 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006534 Genomic DNA No translation available.
AC107377 Genomic DNA No translation available.
AC134407 Genomic DNA No translation available.
KC877674 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

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ModBasei
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

EPDiF5GXF5
jPOSTiF5GXF5
MaxQBiF5GXF5
PeptideAtlasiF5GXF5
PRIDEiF5GXF5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000544778; ENSP00000440854; ENSG00000171634
UCSCiuc010wqm.2 human

Organism-specific databases

HGNCiHGNC:3581 BPTF
OpenTargetsiENSG00000171634

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1473 Eukaryota
KOG1632 Eukaryota
COG5076 LUCA
GeneTreeiENSGT00940000154830

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
BPTF human

Gene expression databases

BgeeiENSG00000171634 Expressed in 223 organ(s), highest expression level in kidney
ExpressionAtlasiF5GXF5 baseline and differential

Family and domain databases

Gene3Di1.20.920.10, 1 hit
InterProiView protein in InterPro
IPR038028 BPTF
IPR036427 Bromodomain-like_sf
IPR018501 DDT_dom
IPR028942 WHIM1_dom
IPR028941 WHIM2_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
PANTHERiPTHR45975 PTHR45975, 2 hits
PfamiView protein in Pfam
PF02791 DDT, 1 hit
PF00628 PHD, 1 hit
PF15612 WHIM1, 1 hit
PF15613 WSD, 1 hit
SMARTiView protein in SMART
SM00571 DDT, 1 hit
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50827 DDT, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF5GXF5_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F5GXF5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: October 3, 2012
Last modified: June 5, 2019
This is version 71 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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