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UniProtKB - F5GX20 (F5GX20_HUMAN)
Protein
Submitted name:
Malonate--CoA ligase ACSF3, mitochondrial
Gene
ACSF3
Organism
Homo sapiens (Human)
Status
Functioni
Keywordsi
Biological process | Lipid metabolismARBA annotation |
Ligand | Nucleotide-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Malonate--CoA ligase ACSF3, mitochondrialImported |
Gene namesi | Name:ACSF3Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:27288, ACSF3 |
VEuPathDBi | HostDB:ENSG00000176715 |
PTM / Processingi
Proteomic databases
MaxQBi | F5GX20 |
PeptideAtlasi | F5GX20 |
PRIDEi | F5GX20 |
ProteomicsDBi | 24287 |
Expressioni
Gene expression databases
Bgeei | ENSG00000176715, Expressed in stomach and 145 other tissues |
ExpressionAtlasi | F5GX20, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 49 – 227 | AMP-bindingInterPro annotationAdd BLAST | 179 |
Phylogenomic databases
GeneTreei | ENSGT00940000157000 |
HOGENOMi | CLU_081705_1_0_1 |
OMAi | GPLYFIQ |
Family and domain databases
Gene3Di | 3.40.50.12780, 1 hit |
InterProi | View protein in InterPro IPR020845, AMP-binding_CS IPR000873, AMP-dep_Synth/Lig IPR042099, ANL_N_sf |
Pfami | View protein in Pfam PF00501, AMP-binding, 1 hit |
PROSITEi | View protein in PROSITE PS00455, AMP_BINDING, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 11 potential isoforms that are computationally mapped.Show allAlign All
F5GX20-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLPHVVLTFR RLGCALASCR LAPARHRGSG LLHTAPVARS DRSAPVFTRA
60 70 80 90 100
LAFGDRIALV DQHGRHTYRE LYSRSLRLSQ EICRLCGCVG GDLREERVSF
110 120 130 140 150
LCANDASYVV AQWASWMSGG VAVPLYRKHP AAQLEYVICD SQSSVVLASQ
160 170 180 190 200
EYLELLSPVV RKLGVPLLPL TPAIYTGAVE EPAEVPVPEQ GWRNKGAMII
210 220 230
YTSGTTGRPK GVLSTHQNIR AVVTGLVHKW AWTKDDV
Computationally mapped potential isoform sequencesi
There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ4G176 | ACSF3_HUMAN | Malonate--CoA ligase ACSF3, mitocho... | ACSF3 PSEC0197 | 576 | Annotation score: | ||
F5H5A1 | F5H5A1_HUMAN | Malonate--CoA ligase ACSF3, mitocho... | ACSF3 | 311 | Annotation score: | ||
A0A3B3ISK9 | A0A3B3ISK9_HUMAN | Malonate--CoA ligase ACSF3, mitocho... | ACSF3 | 646 | Annotation score: | ||
H0YGJ0 | H0YGJ0_HUMAN | Malonate--CoA ligase ACSF3, mitocho... | ACSF3 | 106 | Annotation score: | ||
F5H755 | F5H755_HUMAN | Malonate--CoA ligase ACSF3, mitocho... | ACSF3 | 235 | Annotation score: | ||
F5H2G6 | F5H2G6_HUMAN | Malonate--CoA ligase ACSF3, mitocho... | ACSF3 | 368 | Annotation score: | ||
F5H362 | F5H362_HUMAN | Malonate--CoA ligase ACSF3, mitocho... | ACSF3 | 190 | Annotation score: | ||
F5H3B2 | F5H3B2_HUMAN | Malonate--CoA ligase ACSF3, mitocho... | ACSF3 | 105 | Annotation score: | ||
H0YGC7 | H0YGC7_HUMAN | Malonate--CoA ligase ACSF3, mitocho... | ACSF3 | 183 | Annotation score: | ||
H0YH37 | H0YH37_HUMAN | Malonate--CoA ligase ACSF3, mitocho... | ACSF3 | 144 | Annotation score: | ||
There is more potential isoformShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 237 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009113 Genomic DNA No translation available. AC135782 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000537290; ENSP00000440734; ENSG00000176715 |
UCSCi | uc059ylx.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC009113 Genomic DNA No translation available. AC135782 Genomic DNA No translation available. |
3D structure databases
SMRi | F5GX20 |
ModBasei | Search... |
Proteomic databases
MaxQBi | F5GX20 |
PeptideAtlasi | F5GX20 |
PRIDEi | F5GX20 |
ProteomicsDBi | 24287 |
Protocols and materials databases
Antibodypediai | 2033, 113 antibodies from 19 providers |
Genome annotation databases
Ensembli | ENST00000537290; ENSP00000440734; ENSG00000176715 |
UCSCi | uc059ylx.1, human |
Organism-specific databases
HGNCi | HGNC:27288, ACSF3 |
OpenTargetsi | ENSG00000176715 |
VEuPathDBi | HostDB:ENSG00000176715 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000157000 |
HOGENOMi | CLU_081705_1_0_1 |
OMAi | GPLYFIQ |
Miscellaneous databases
ChiTaRSi | ACSF3, human |
Gene expression databases
Bgeei | ENSG00000176715, Expressed in stomach and 145 other tissues |
ExpressionAtlasi | F5GX20, baseline and differential |
Family and domain databases
Gene3Di | 3.40.50.12780, 1 hit |
InterProi | View protein in InterPro IPR020845, AMP-binding_CS IPR000873, AMP-dep_Synth/Lig IPR042099, ANL_N_sf |
Pfami | View protein in Pfam PF00501, AMP-binding, 1 hit |
PROSITEi | View protein in PROSITE PS00455, AMP_BINDING, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | F5GX20_HUMAN | |
Accessioni | F5GX20Primary (citable) accession number: F5GX20 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 28, 2011 |
Last sequence update: | June 28, 2011 | |
Last modified: | January 19, 2022 | |
This is version 59 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |