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UniProtKB - F5GWX9 (F5GWX9_HUMAN)
Protein
Submitted name:
G-protein-coupled receptor family C group 5 member D
Gene
GPRC5D
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- G protein-coupled receptor activity Source: InterPro
Keywordsi
Molecular function | G-protein coupled receptorARBA annotation, Receptor, Transducer |
Names & Taxonomyi
Protein namesi | Submitted name: G-protein-coupled receptor family C group 5 member D |
Gene namesi | Name:GPRC5D |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:13310, GPRC5D |
VEuPathDBi | HostDB:ENSG00000111291 |
Subcellular locationi
Plasma membrane
- Cell membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 22 – 47 | HelicalSequence analysisAdd BLAST | 26 | |
Transmembranei | 59 – 82 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 94 – 115 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
Cell membraneARBA annotation, MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000111291, Expressed in hair follicle and 115 other tissues |
ExpressionAtlasi | F5GWX9, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 16 – 116 | G_PROTEIN_RECEP_F3_4InterPro annotationAdd BLAST | 101 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00950000182961 |
HOGENOMi | CLU_2054974_0_0_1 |
OMAi | RSCKQDC |
Family and domain databases
InterProi | View protein in InterPro IPR017978, GPCR_3_C |
Pfami | View protein in Pfam PF00003, 7tm_3, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F5GWX9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MYKDCIESTG DYFLLCDAEG PWGIILESLA ILGIVVTILL LLAFLFLMRK
60 70 80 90 100
IQDCSQWNVL PTQLLFLLSV LGLFGLAFAF IIELNQQTAP VRYFLFGVLF
110 120
ALCFSCLLAH ASNLVKLVRG
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ9NZD1 | GPC5D_HUMAN | G-protein coupled receptor family C... | GPRC5D | 345 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 120 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007688 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000541128.1; ENSP00000440530.1; ENSG00000111291.8 |
UCSCi | uc058ljz.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007688 Genomic DNA No translation available. |
3D structure databases
SMRi | F5GWX9 |
ModBasei | Search... |
Proteomic databases
ProteomicsDBi | 24252 |
Protocols and materials databases
Antibodypediai | 11949, 221 antibodies from 28 providers |
Genome annotation databases
Ensembli | ENST00000541128.1; ENSP00000440530.1; ENSG00000111291.8 |
UCSCi | uc058ljz.1, human |
Organism-specific databases
HGNCi | HGNC:13310, GPRC5D |
OpenTargetsi | ENSG00000111291 |
VEuPathDBi | HostDB:ENSG00000111291 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00950000182961 |
HOGENOMi | CLU_2054974_0_0_1 |
OMAi | RSCKQDC |
Gene expression databases
Bgeei | ENSG00000111291, Expressed in hair follicle and 115 other tissues |
ExpressionAtlasi | F5GWX9, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR017978, GPCR_3_C |
Pfami | View protein in Pfam PF00003, 7tm_3, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | F5GWX9_HUMAN | |
Accessioni | F5GWX9Primary (citable) accession number: F5GWX9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 28, 2011 |
Last sequence update: | June 28, 2011 | |
Last modified: | May 25, 2022 | |
This is version 55 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |