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Protein
Submitted name:

Long-chain-fatty-acid--CoA ligase 3

Gene

ACSL3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Long-chain-fatty-acid--CoA ligase 3Imported
Gene namesi
Name:ACSL3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000123983.13
HGNCiHGNC:3570 ACSL3

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000123983

PTM / Processingi

Proteomic databases

MaxQBiF5GWH2
PeptideAtlasiF5GWH2
PRIDEiF5GWH2

Expressioni

Gene expression databases

BgeeiENSG00000123983 Expressed in 233 organ(s), highest expression level in endothelial cell
ExpressionAtlasiF5GWH2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF5GWH2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 140AMP-bindingInterPro annotationAdd BLAST139

Phylogenomic databases

eggNOGiKOG1256 Eukaryota
COG1022 LUCA
GeneTreeiENSGT00690000101725

Family and domain databases

InterProiView protein in InterPro
IPR000873 AMP-dep_Synth/Lig
PfamiView protein in Pfam
PF00501 AMP-binding, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.iShow all

F5GWH2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLGQKPKTNI AIFCETRAEW MIAAQACFMY NFQLVTLYAT LGGPAIVHAL
60 70 80 90 100
NETEVTNIIT SKELLQTKLK DIVSLVPRLR HIITVDGKPP TWSEFPKGII
110 120 130 140
VHTMAAVEAL GAKASMENQP HSKPLPSDIA VIMYTSGSTG L
Length:141
Mass (Da):15,393
Last modified:June 28, 2011 - v1
Checksum:iD89E06B5DA1A47C7
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O95573ACSL3_HUMAN
Long-chain-fatty-acid--CoA ligase 3
ACSL3 ACS3, FACL3, LACS3
720Annotation score:
C9JC11C9JC11_HUMAN
Long-chain-fatty-acid--CoA ligase 3
ACSL3
88Annotation score:
F5H062F5H062_HUMAN
Long-chain-fatty-acid--CoA ligase 3
ACSL3
95Annotation score:
H7BYZ7H7BYZ7_HUMAN
Long-chain-fatty-acid--CoA ligase 3
ACSL3
18Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei141Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013476 Genomic DNA No translation available.
AC016712 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000540115; ENSP00000441643; ENSG00000123983
UCSCiuc061tbp.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC013476 Genomic DNA No translation available.
AC016712 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF5GWH2
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF5GWH2
PeptideAtlasiF5GWH2
PRIDEiF5GWH2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000540115; ENSP00000441643; ENSG00000123983
UCSCiuc061tbp.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000123983.13
HGNCiHGNC:3570 ACSL3
OpenTargetsiENSG00000123983
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1256 Eukaryota
COG1022 LUCA
GeneTreeiENSGT00690000101725

Miscellaneous databases

ChiTaRSiACSL3 human

Gene expression databases

BgeeiENSG00000123983 Expressed in 233 organ(s), highest expression level in endothelial cell
ExpressionAtlasiF5GWH2 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000873 AMP-dep_Synth/Lig
PfamiView protein in Pfam
PF00501 AMP-binding, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF5GWH2_HUMAN
AccessioniPrimary (citable) accession number: F5GWH2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: September 12, 2018
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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