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Entry version 49 (11 Dec 2019)
Sequence version 1 (28 Jun 2011)
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Protein

RNA helicase

Gene

ddx55

Organism
Cavenderia fasciculata (strain SH3) (Slime mold) (Dictyostelium fasciculatum)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicaseSAAS annotationImported, Hydrolase, RNA-bindingSAAS annotation
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RNA helicaseSAAS annotation (EC:3.6.4.13SAAS annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ddx55Imported
ORF Names:DFA_07300Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCavenderia fasciculata (strain SH3) (Slime mold) (Dictyostelium fasciculatum)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1054147 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAmoebozoaEvoseaEumycetozoaDictyostelidsAcytostelialesCavenderiaceaeCavenderia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000007797 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini360 – 392GATA-typeInterPro annotationAdd BLAST33
Domaini569 – 597Q_MOTIFInterPro annotationAdd BLAST29
Domaini600 – 780Helicase ATP-bindingInterPro annotationAdd BLAST181
Domaini814 – 975Helicase C-terminalInterPro annotationAdd BLAST162

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 67DisorderedSequence analysisAdd BLAST67
Regioni151 – 222DisorderedSequence analysisAdd BLAST72
Regioni248 – 302DisorderedSequence analysisAdd BLAST55
Regioni314 – 369DisorderedSequence analysisAdd BLAST56
Regioni420 – 507DisorderedSequence analysisAdd BLAST88
Regioni1097 – 1288DisorderedSequence analysisAdd BLAST192

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili543 – 563Sequence analysisAdd BLAST21
Coiled coili1055 – 1082Sequence analysisAdd BLAST28

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi569 – 597Q motifPROSITE-ProRule annotationAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi10 – 37PolarSequence analysisAdd BLAST28
Compositional biasi38 – 56PolyampholyteSequence analysisAdd BLAST19
Compositional biasi153 – 173PolarSequence analysisAdd BLAST21
Compositional biasi185 – 222PolarSequence analysisAdd BLAST38
Compositional biasi277 – 300PolarSequence analysisAdd BLAST24
Compositional biasi321 – 350PolarSequence analysisAdd BLAST30
Compositional biasi420 – 499PolarSequence analysisAdd BLAST80
Compositional biasi1131 – 1154AcidicSequence analysisAdd BLAST24
Compositional biasi1155 – 1232PolyampholyteSequence analysisAdd BLAST78
Compositional biasi1233 – 1249PolarSequence analysisAdd BLAST17
Compositional biasi1251 – 1272PolyampholyteSequence analysisAdd BLAST22
Compositional biasi1273 – 1288BasicSequence analysisAdd BLAST16

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DEAD box helicase family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K14809

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00202 ZnF_GATA, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.50.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR025313 DUF4217
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
IPR000679 Znf_GATA
IPR013088 Znf_NHR/GATA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00270 DEAD, 1 hit
PF13959 DUF4217, 1 hit
PF00320 GATA, 1 hit
PF00271 Helicase_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00487 DEXDc, 1 hit
SM01178 DUF4217, 1 hit
SM00490 HELICc, 1 hit
SM00401 ZnF_GATA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS50114 GATA_ZN_FINGER_2, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F4PW16-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIIVGSWLVP TRVQPTNQPT NSTTINNNNN NNDENSSKNN SIKDEVPVRD
60 70 80 90 100
TSCYNKNDDE EEEEEDTRMN IEIRNISTTK DQREGESRCL GVLSQLHVET
110 120 130 140 150
FRINQSIETI RKDITHSQKR YTLADYRMLV ENLTPIFKGM LSVLEEYGSE
160 170 180 190 200
LNGQPVNEPT QTTGTTTTNQ KKQRSSKQHI ESSSRKKPTN SPILSPVNNP
210 220 230 240 250
NNINNNSNQN NNNNQFYGQP TLSSSTLSTL TSFKLPPLHT QLHHSSLQPL
260 270 280 290 300
PFLHSPPKLP PSPRDHHHHS PFDSPRQAIL GGSTTYGLAN SPTTTNPFEL
310 320 330 340 350
DDTPAKPPDI VKEVPPEPGH LTDGTSTTNS TTATTNMAPD NSTSMSTSMR
360 370 380 390 400
AKRGRGRPPQ SKPNHCARCK RTDTPEWRKG ENGIDLCNAC GLQFMKRNRK
410 420 430 440 450
DKETVDLLLS SFQHVQYQQQ QQQQQPVDGS LEFQSEQSVD QQTLQQHQHQ
460 470 480 490 500
QYQTSHPQLP QLQTYQHYTQ SSPRYHTPPE ESIYINNNNN NSNNNNTNRT
510 520 530 540 550
TTPPPPPVIS QLPYIDFNYL RPNNSPPPYT TTIHHPFNTS TNNNNNSNNN
560 570 580 590 600
KKLNRERERM NLTGGGAKWS TVRPTISDHV LGIIKKLGFD TMTPVQSATI
610 620 630 640 650
PLFLSNKDVL VEACTGSGKT LSFIIPIIEI LLKKQPEELT KHQVLAVIVT
660 670 680 690 700
PTRELAVQIF GILEQFVHGL DHIKRLLLIG GTEVYEDVQK FNKDGGNVIV
710 720 730 740 750
ATPGRLEDVL SRVERNMKLK EFEMLILDEA DRLLDMGFDT ALNAVLDRLP
760 770 780 790 800
KQRRTGLFSA TQTTELKELA RMGMRNPVKV SVAVQQKGTN QVSAIPSTLE
810 820 830 840 850
NRYTMLEPSE KFGVLADFMD KNMNNSKIIV YFLTCADVDY FSSLMTKMSQ
860 870 880 890 900
FKDRVKDIFS LHGKVPHERR KFVFDKFSAK DSGVIFVTDL VSRGIDFPSV
910 920 930 940 950
DWVIQYDAPQ DPKTFIHRIG RTARMGRTGN AMLYLSKAED DYLEFMRLRK
960 970 980 990 1000
VSMVETPKPD TLALEHYTKE MRRVILSNRQ IMERSIVAFV SYARAYKEHT
1010 1020 1030 1040 1050
CSYIFVTRKL DFGSLAHGYG LLRMPKMPEL RFFNPDTWAS GVSREDIEKV
1060 1070 1080 1090 1100
PYVDKKREAK RLIQLKESKK KQEKREKKKE AKVKKILSIS GLKMEDLTGK
1110 1120 1130 1140 1150
KQVKEEENED DSDESEDEVE ALMRADQDQE VKQEEDEDEE EEEDSEDDSS
1160 1170 1180 1190 1200
EEEEETTKTP VRKSAPKIVK DEEQLKQEDR ETVNRDYLEM KKNNKRKNRG
1210 1220 1230 1240 1250
FHGDLDDFDS IEKEIKLEIK KKKQEEKENK SKSTTTTATT TTTGGITKPL
1260 1270 1280
SKNAEKKKNK NKKPEFAPKK TYHKKVQNSS RQKKSSRK
Length:1,288
Mass (Da):147,003
Last modified:June 28, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i29D80B58D73D2CE3
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GL883013 Genomic DNA Translation: EGG20180.1

NCBI Reference Sequences

More...
RefSeqi
XP_004367163.1, XM_004367106.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
EGG20180; EGG20180; DFA_07300

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
14872387

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
dfa:DFA_07300

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL883013 Genomic DNA Translation: EGG20180.1
RefSeqiXP_004367163.1, XM_004367106.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblProtistsiEGG20180; EGG20180; DFA_07300
GeneIDi14872387
KEGGidfa:DFA_07300

Phylogenomic databases

KOiK14809

Family and domain databases

CDDicd00202 ZnF_GATA, 1 hit
Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR025313 DUF4217
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
IPR000679 Znf_GATA
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF13959 DUF4217, 1 hit
PF00320 GATA, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM01178 DUF4217, 1 hit
SM00490 HELICc, 1 hit
SM00401 ZnF_GATA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS50114 GATA_ZN_FINGER_2, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF4PW16_CAVFA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F4PW16
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: December 11, 2019
This is version 49 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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