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UniProtKB - F4KCC2 (PRT6_ARATH)

Entry version 70 (02 Jun 2021)
Sequence version 1 (28 Jun 2011)
Previous versions | rss
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Protein

E3 ubiquitin-protein ligase PRT6

Gene

PRT6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Ubiquitin protein ligase which is a component of the N-end rule pathway with arginine specificity, and functions with the arginyltransferases ATE1 and ATE2. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (PubMed:17572409, PubMed:19255443, PubMed:19620738, PubMed:22020282).

Does not participate in degradation of proteins with N-terminal Phe or Leu (PubMed:17572409).

The N-end rule pathway regulates seed after-ripening, seedling sugar sensitivity, seedling lipid breakdown, and abscisic acid (ABA) sensitivity of germination (PubMed:19255443).

The N-end rule pathway regulates various aspects of leaf and shoot development (PubMed:19620738).

Involved in the ubiquitination and subsequent degradation of RAP2-12, an activator of hypoxic gene expression. The ubiquitination occurs after the N-arginylation of RAP2-12 by ATE1 or ATE2 under aerobic conditions (PubMed:22020282).

The end-rule pathway plays a role in regulating the timing and amplitude of the immune response following infection with the bacterial pathogen Pseudomonas syringae pv tomato (PubMed:27173012, PubMed:30117535).

Regulates the biosynthesis of plant-defense metabolites such as glucosinolates, and the biosynthesis and response to the phytohormone jasmonate (JA), which plays a key role in plant immunity (PubMed:27173012).

Controls the expression of specific defense-response genes, activates the synthesis pathway for the phytoalexin camalexin, and influences basal resistance to the hemibiotroph pathogen Pseudomonas syringae pv tomato (PubMed:30117535).

Coordinates the mobilization of seed storage reserves and regulates the abundance and activities of several proteases following seed germination (PubMed:29168982).

7 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine. EC:2.3.2.27

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.Curated
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri119 – 189UBR-typePROSITE-ProRule annotationAdd BLAST71
Zinc fingeri1395 – 1440RING-type; degeneratePROSITE-ProRule annotationAdd BLAST46

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processPlant defense, Ubl conjugation pathway
LigandMetal-binding, Zinc

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
E3 ubiquitin-protein ligase PRT6Curated (EC:2.3.2.27)
Alternative name(s):
Protein GREENING AFTER EXTENDED DARKNESS 11 Publication
Protein PROTEOLYSIS 61 Publication
RING-type E3 ubiquitin transferase PRT6Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PRT61 Publication
Synonyms:CER31 Publication, GED11 Publication
Ordered Locus Names:At5g02310/At5g02300Imported
ORF Names:T1E22.70/T1E22.60Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT5G02310

The Arabidopsis Information Resource

More...TAIRi		locus:2180147, AT5G02310

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Reduced seed germination potential and inhibition of seedling establishment by sucrose (PubMed:19255443). Exhibits abnormal shoot and leaf development (PubMed:19620738). Increased tolerance of seedlings to submergence and starvation (PubMed:25667318).3 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004317201 – 2006E3 ubiquitin-protein ligase PRT6Add BLAST2006

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F4KCC2

PRoteomics IDEntifications database

More...PRIDEi		F4KCC2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		226480

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		F4KCC2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		F4KCC2, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		F4KCC2, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		3702.AT5G02310.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

12006
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		F4KCC2

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1167 – 1186DisorderedSequence analysisAdd BLAST20
Regioni1338 – 1380DisorderedSequence analysisAdd BLAST43

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1172 – 1186Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi1350 – 1366Polar residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UBR1 family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri119 – 189UBR-typePROSITE-ProRule annotationAdd BLAST71
Zinc fingeri1395 – 1440RING-type; degeneratePROSITE-ProRule annotationAdd BLAST46

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1139, Eukaryota
KOG1140, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_001801_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F4KCC2

Database of Orthologous Groups

More...OrthoDBi		81415at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.10.2670, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR042065, E3_ELL-like
IPR044046, E3_ligase_UBR-like_C
IPR039164, UBR1-like
IPR036390, WH_DNA-bd_sf
IPR003126, Znf_UBR

The PANTHER Classification System

More...PANTHERi		PTHR21497, PTHR21497, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF18995, PRT6_C, 1 hit
PF02207, zf-UBR, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00396, ZnF_UBR1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46785, SSF46785, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51157, ZF_UBR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F4KCC2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
METNSSLFGL VSPSSHDLVI ERLASVGVPK KYRSKRGLVE FVRANPAKIS 
        60         70         80         90        100
ELVSALLPTD DDVKLGLKEA RERPRKSAVS PTMKKRFRES MNMLQWLMFQ 
       110        120        130        140        150
DEPDVSLRNL AKLNLDQRGV CGSVWGQNDI AYRCRTCEND PTCAICVPCF 
       160        170        180        190        200
QNGDHNSHDY SIIYTGGGCC DCGDETAWKP DGFCSNHKGS EQIRPLSENL 
       210        220        230        240        250
ANSVGPILDA LFTCWNNKLL SAESSGQKGA RSNDTLVILQ KMSNELTFIV 
       260        270        280        290        300
VEMLLEFSMS SESLLSFVSR RIISSSGLLS ILLKAERFLD QDVMKKLHDL 
       310        320        330        340        350
FLKLIGDPVF KCEFAKAFVS YYPVVISEVV KQGTDNAFKK YPLLSTFSVQ 
       360        370        380        390        400
ILTVPTLTPF LVKEMNLLAM LLGCLSDIFV SCSGEDGLLQ ATKLERLCET 
       410        420        430        440        450
SERVIGDLKF VMSHAIVSKY ATHEHRELSR SWLTLLTFAQ GMNPLKRETG 
       460        470        480        490        500
IPIDEENDYM HLFFVLGHSI AVIHSLLVNG TYSAASDEEI ENDRNAKEEF 
       510        520        530        540        550
DKCDGDGERY AKVGRLSHED SVCTAIVSSS SFDSSMASEV HKIDPFHALL 
       560        570        580        590        600
PSSAIYLIRE CLKVLETCLG NDEGISKFLC KLSSSSGRNI PESKMSWPRR 
       610        620        630        640        650
DLLNVETGGS VSSNLASSSR DPSTGLSPLC GDIQTNLSLD NVCGPYGVVQ 
       660        670        680        690        700
TDVTADSKRV SCNSADLTKN ASGLRILGLC DWPDIHYDVS SQAISVHLPL 
       710        720        730        740        750
HRLLSLLIQK ALRICYGESA SYNGVSISHE IPHADFFSSV IGDFHPCGFS 
       760        770        780        790        800
ALVMEHVLQI RVFCAQVIAG MWKKNGDSAL VSCEWYRSVR WSEQGLELDL 
       810        820        830        840        850
FLLQCCAALA PADSYVDKLL SRFGLSSYLS LNPDITNEYE PVLVQEMLGL 
       860        870        880        890        900
LIQILQERRF CGLSTAESLR REIIFKLATG DFTHSQLVKS LPRDLSKSDE 
       910        920        930        940        950
LQEVLDDVSV YCNPSGMNQG KYSLQSSCWK ELDLYHPRWQ SRDLQSAEER 
       960        970        980        990       1000
FSRYCGVSAL TTQLPRWRMI YPPLKGLARI GTCKATFQII SSALYYALQS 
      1010       1020       1030       1040       1050
GTSVKSRAPD GVLITALQLL SLSLDICTQQ RQSNSQDCCL ENSIPILELA 
      1060       1070       1080       1090       1100
GLEIIGIAQG TEKESLLSLL VSLMKTRMGD GRHQFPEPGS CNISSWIGNL 
      1110       1120       1130       1140       1150
LKKFSAIDSV CMNLLQSLAP EVVGQSGFDK VMSGSTSDEK RKAKAKERQA 
      1160       1170       1180       1190       1200
AIMAKMKAEQ SKFLSTLSSS MDDDDPRSEF ETSDSVMEHD SEIAVREVCS 
      1210       1220       1230       1240       1250
LCHDPDSKDP VSFLIFLQKS KLLSFVDRGP PSWDQCPQSE KKISVDGAPD 
      1260       1270       1280       1290       1300
LLRMNASSDS LRISSPLMLQ LSDDTISESA NMIESIKARL IGNGQTEKRS 
      1310       1320       1330       1340       1350
SDGRGKDESN MESLEIAMYQ TVRNKIENMI NQSLTRVDHQ PHEAENCSEK 
      1360       1370       1380       1390       1400
NSVGGPSTLQ GRFPDIRSRQ TSRRPDAGSD GFHPIDCDGV YLSSCGHAVH 
      1410       1420       1430       1440       1450
QSCLERYLKS LKERSGRRTV FEGAHIVDLK KKEFLCPVCR RLANSVLPEC 
      1460       1470       1480       1490       1500
PGDLCSVSKL QDSPRTKLRR KDALQPSLWL SEALCLLRSA AEVIEDGDRG 
      1510       1520       1530       1540       1550
KTVTPQGDGP RRKDLKSVSK MLWDFYFPKP EDKTLKRLWL PPQSIVMWDT 
      1560       1570       1580       1590       1600
LKYSLISMEI GTRFAKNSML PVYCIDSLYE ELKTSKGTIL SVLLRVVQSS 
      1610       1620       1630       1640       1650
RTKNTIHVRQ RFVGMKHLAE SICYGVSSSS SSSIFGSEGT TGSLKNIDLL 
      1660       1670       1680       1690       1700
WNRASDPVLA HDPFSSLMWA LFCLPFPFLT CEESLLSLVH IFHSVSLVQT 
      1710       1720       1730       1740       1750
VIAYCACRPS ELSELNFGEN LLNDISNALR ESGGWEYFRS NNMDLSCDIK 
      1760       1770       1780       1790       1800
DTIRKYSLPF LRRCALLWKL LKSTPRKLHE ESDMFDLPSD PTTDNMDFIY 
      1810       1820       1830       1840       1850
SPQSELNHVQ ELEKMFNIPP IDIILNDELL RSSTQIWLQH FQREYRVNRV 
      1860       1870       1880       1890       1900
KRSLCITPVV PFQLMKLPNL YQDLLQRCIK KRCVNCTKVI EEPVLCLLCG 
      1910       1920       1930       1940       1950
SLCSPIWSPC CRESGCPNHA ITCGAGTGVF LLIRRTTILL QRFARQSPWP 
      1960       1970       1980       1990       2000
SPYLDTFGEE DIDMIRGKRL YLNEERYAAL TYLVGSHGLD RSSKVLGQTT 

IGAVLH
Length:2,006
Mass (Da):223,964
Last modified:June 28, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i77B373F169C77DCC
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8BFH3A0A1P8BFH3_ARATH
E3 ubiquitin-protein ligase
PRT6 proteolysis 6, At5g02300, At5g02310, T1E22.70, T1E22_70
1,924Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB85535 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes At5g02300 and At5g02310.Curated
The sequence CAB85536 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes At5g02300 and At5g02310.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1341P → H in CAA65198 (PubMed:8811860).Curated1
Sequence conflicti1430Missing in CAA65198 (PubMed:8811860).Curated1
Sequence conflicti1838L → F in CAA65198 (PubMed:8811860).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL162874 Genomic DNA Translation: CAB85535.1 Sequence problems.
AL162874 Genomic DNA Translation: CAB85536.1 Sequence problems.
CP002688 Genomic DNA Translation: AED90457.1
CP002688 Genomic DNA Translation: ANM70335.1
X95962 Genomic DNA Translation: CAA65198.1

Protein sequence database of the Protein Information Resource

More...PIRi		T48251
T48252

NCBI Reference Sequences

More...RefSeqi		NP_001318457.1, NM_001342651.1
NP_195851.2, NM_120309.2

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT5G02310.1; AT5G02310.1; AT5G02310
AT5G02310.3; AT5G02310.3; AT5G02310

Database of genes from NCBI RefSeq genomes

More...GeneIDi		830916

Gramene; a comparative resource for plants

More...Gramenei		AT5G02310.1; AT5G02310.1; AT5G02310
AT5G02310.3; AT5G02310.3; AT5G02310

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ath:AT5G02310

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162874 Genomic DNA Translation: CAB85535.1 Sequence problems.
AL162874 Genomic DNA Translation: CAB85536.1 Sequence problems.
CP002688 Genomic DNA Translation: AED90457.1
CP002688 Genomic DNA Translation: ANM70335.1
X95962 Genomic DNA Translation: CAA65198.1
PIRiT48251
T48252
RefSeqiNP_001318457.1, NM_001342651.1
NP_195851.2, NM_120309.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6LHNX-ray2.50A119-189[»]
SMRiF4KCC2
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi3702.AT5G02310.1

PTM databases

iPTMnetiF4KCC2

Proteomic databases

PaxDbiF4KCC2
PRIDEiF4KCC2
ProteomicsDBi226480

Genome annotation databases

EnsemblPlantsiAT5G02310.1; AT5G02310.1; AT5G02310
AT5G02310.3; AT5G02310.3; AT5G02310
GeneIDi830916
GrameneiAT5G02310.1; AT5G02310.1; AT5G02310
AT5G02310.3; AT5G02310.3; AT5G02310
KEGGiath:AT5G02310

Organism-specific databases

AraportiAT5G02310
TAIRilocus:2180147, AT5G02310

Phylogenomic databases

eggNOGiKOG1139, Eukaryota
KOG1140, Eukaryota
HOGENOMiCLU_001801_1_0_1
InParanoidiF4KCC2
OrthoDBi81415at2759

Enzyme and pathway databases

UniPathwayiUPA00143

Miscellaneous databases

Protein Ontology

More...PROi		PR:F4KCC2

Gene expression databases

ExpressionAtlasiF4KCC2, baseline and differential
GenevisibleiF4KCC2, AT

Family and domain databases

Gene3Di1.10.10.2670, 1 hit
InterProiView protein in InterPro
IPR042065, E3_ELL-like
IPR044046, E3_ligase_UBR-like_C
IPR039164, UBR1-like
IPR036390, WH_DNA-bd_sf
IPR003126, Znf_UBR
PANTHERiPTHR21497, PTHR21497, 1 hit
PfamiView protein in Pfam
PF18995, PRT6_C, 1 hit
PF02207, zf-UBR, 1 hit
SMARTiView protein in SMART
SM00396, ZnF_UBR1, 1 hit
SUPFAMiSSF46785, SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS51157, ZF_UBR, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPRT6_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F4KCC2
Secondary accession number(s): Q96248, Q9LZ94, Q9LZ95
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 4, 2015
Last sequence update: June 28, 2011
Last modified: June 2, 2021
This is version 70 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
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