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UniProtKB - F4K4G6 (F4K4G6_ARATH)

Entry version 61 (07 Oct 2020)
Sequence version 1 (28 Jun 2011)
Previous versions | rss
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Protein
Submitted name:

RING/FYVE/PHD zinc finger superfamily protein

Gene

At5g36670

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RING/FYVE/PHD zinc finger superfamily proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At5g36670Imported
ORF Names:F24C7.4Imported, F24C7_4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT5G36670

The Arabidopsis Information Resource

More...TAIRi		locus:2832118, AT5G36670

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F4K4G6

PRoteomics IDEntifications database

More...PRIDEi		F4K4G6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		204043

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini650 – 695PHD-typeInterPro annotationAdd BLAST46

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni122 – 164DisorderedSequence analysisAdd BLAST43
Regioni245 – 390DisorderedSequence analysisAdd BLAST146
Regioni475 – 525DisorderedSequence analysisAdd BLAST51
Regioni1004 – 1032DisorderedSequence analysisAdd BLAST29
Regioni1045 – 1145DisorderedSequence analysisAdd BLAST101

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi122 – 143PolyampholyteSequence analysisAdd BLAST22
Compositional biasi256 – 287PolarSequence analysisAdd BLAST32
Compositional biasi331 – 390PolyampholyteSequence analysisAdd BLAST60
Compositional biasi1004 – 1018PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1045 – 1113PolyampholyteSequence analysisAdd BLAST69
Compositional biasi1114 – 1137PolarSequence analysisAdd BLAST24

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502SD3A, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_284754_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F4K4G6

Database of Orthologous Groups

More...OrthoDBi		166926at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR017956, AT_hook_DNA-bd_motif
IPR032308, Jas
IPR019786, Zinc_finger_PHD-type_CS
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00628, PHD, 1 hit
PF16135, TDBD, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00929, ATHOOK

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00384, AT_hook, 3 hits
SM00249, PHD, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57903, SSF57903, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01359, ZF_PHD_1, 1 hit
PS50016, ZF_PHD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

F4K4G6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLETNEQKGF DLNVCASIED FSESDIKAEG ETDSLVDGNV ENVIEIKDKK 
        60         70         80         90        100
KVIEREILIT RRVLRSGSVA RDLVNSDKHC KAVKRKGNVV SGGSSVDEVK 
       110        120        130        140        150
EEVKQECVKS LVPEEIRGDD FRSEVKVESK DDRSDDGKEE KVQRKRGRPR 
       160        170        180        190        200
KFGMSSQSDD NGLISNCKLR TSLGKKKELV GDDNVEKLVG GSCFNKEKAE 
       210        220        230        240        250
VKLEHGEYAE DKEILGLDFR SQVKVEIKDD ECGIVELHDE ELQVKRKRGR 
       260        270        280        290        300
PRKVQISSQS DESRPNTNCK LARTPELSSQ SSVDRISLSR LRGRPPKTKE 
       310        320        330        340        350
TSVSLYIEKG PESNGRRMVR KRGRPPTPQK KRKSGMTDES DWKAKKRLKL 
       360        370        380        390        400
CESPLESRHN NPLIDDERMI GEQRSKQTEA GGHSRSKSKK MLSDRILQLL 
       410        420        430        440        450
LTAGWTVEYR PRNGRAYQDA VYLNPEGKTH WSVTKAYQVY KKQLESNPND 
       460        470        480        490        500
QKNSTTGSGF GLLPEEDLHL LERTIQKKRS DTGKQRSKLK DRDTNDILVS 
       510        520        530        540        550
TKGTGKIKRE EKHSRKRCTP SARSSLKDVD SKEDGYILFE GKRTMLGWMI 
       560        570        580        590        600
DSTIVPLNGK VQCMDCKKTD ILLEGIITKE GIRCNCCDEV FSVLDFEVHA 
       610        620        630        640        650
GGNRNQPFKS LYLEGGNSLL QCLHESMNKQ SESQLKGYHF VDFGSGDPND 
       660        670        680        690        700
DTCGICGDGG DLICCDGCPS TFHQSCLDIK KFPSGAWYCY NCSCKFCEKD 
       710        720        730        740        750
EAAKHETSTL PSLSSCRLCE EKCSKHYPHT LADHQACINQ DGTVPGERST 
       760        770        780        790        800
DSFCGKYCQE LFEELQLFIG VKHPLPEGFS WSFLRRFELP SEVADCDISE 
       810        820        830        840        850
KIAYNAKMAV AFSVMDECFS PLVDHRSGVN LLQNIVYNFG SNFHRLDFSS 
       860        870        880        890        900
FLTAVLERGD EIIAVASIRI HGNQLAEMPF IGTRYMYRRQ GMCRRLMDGI 
       910        920        930        940        950
ESFVAYFSQM FLAISEVLLD VWQFCCYPAC FGDGPFCFFS GFGFAPVNDS 
       960        970        980        990       1000
EKKTIKNLNL LVFPGVDMLG KSLVKEKITD SVVSSPNGLV LLAPEMTLPV 
      1010       1020       1030       1040       1050
DVEENKPEES KDSAHERNCA TAGVESPSNP VDSCLKLTYV EEGDNDRESN 
      1060       1070       1080       1090       1100
LKLLDGSVEE KEDTKKLTDI DINSLPDEVD DSHADQSDTK EQEIDDKEDK 
      1110       1120       1130       1140       1150
TPLSDDGCEG KAEGTKESNQ QPDSNKVDNS QPLGNGGTGE ELGNRTLALK 
      1160       1170       1180       1190 
REVTPTLRAS PRLIQRSWRT SRVNQKFTGT TNAVLLDSPH RCV
Length:1,193
Mass (Da):133,770
Last modified:June 28, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE01D4CD0F05E4405
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4K4H9F4K4H9_ARATH
Acyl-CoA N-acyltransferase with RIN...
MPK17.2 At5g36740
1,169Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8BG30A0A1P8BG30_ARATH
Acyl-CoA N-acyltransferase with RIN...
MPK17.2 At5g36670, At5g36740, F24C7.4, F24C7_4
902Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8BA02A0A1P8BA02_ARATH
Acyl-CoA N-acyltransferase with RIN...
MPK17.2 At5g36740
1,026Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8BG27A0A1P8BG27_ARATH
RING/FYVE/PHD zinc finger superfami...
At5g36670, F24C7.4, F24C7_4
1,183Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8BFX4A0A1P8BFX4_ARATH
RING/FYVE/PHD zinc finger superfami...
At5g36670, F24C7.4, F24C7_4
1,040Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
CP002688 Genomic DNA Translation: AED94096.1

NCBI Reference Sequences

More...RefSeqi		NP_568537.1, NM_123024.2

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT5G36670.1; AT5G36670.1; AT5G36670

Database of genes from NCBI RefSeq genomes

More...GeneIDi		833632

Gramene; a comparative resource for plants

More...Gramenei		AT5G36670.1; AT5G36670.1; AT5G36670

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002688 Genomic DNA Translation: AED94096.1
RefSeqiNP_568537.1, NM_123024.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PaxDbiF4K4G6
PRIDEiF4K4G6
ProteomicsDBi204043

Genome annotation databases

EnsemblPlantsiAT5G36670.1; AT5G36670.1; AT5G36670
GeneIDi833632
GrameneiAT5G36670.1; AT5G36670.1; AT5G36670

Organism-specific databases

AraportiAT5G36670
TAIRilocus:2832118, AT5G36670

Phylogenomic databases

eggNOGiENOG502SD3A, Eukaryota
HOGENOMiCLU_284754_0_0_1
InParanoidiF4K4G6
OrthoDBi166926at2759

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR017956, AT_hook_DNA-bd_motif
IPR032308, Jas
IPR019786, Zinc_finger_PHD-type_CS
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00628, PHD, 1 hit
PF16135, TDBD, 1 hit
PRINTSiPR00929, ATHOOK
SMARTiView protein in SMART
SM00384, AT_hook, 3 hits
SM00249, PHD, 1 hit
SUPFAMiSSF57903, SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS01359, ZF_PHD_1, 1 hit
PS50016, ZF_PHD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF4K4G6_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F4K4G6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: October 7, 2020
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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