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UniProtKB - F4JU70 (COAC2_ARATH)
Protein
Mitochondrial carrier protein CoAc2
Gene
COAC2
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Required for the accumulation of coenzyme A in the mitochondrial matrix.
1 PublicationGO - Molecular functioni
- coenzyme A transmembrane transporter activity Source: TAIR
GO - Biological processi
- mitochondrial coenzyme A transmembrane transport Source: UniProtKB
Keywordsi
Biological process | Transport |
Protein family/group databases
TCDBi | 2.A.29.12.6, the mitochondrial carrier (mc) family |
Names & Taxonomyi
Protein namesi | Recommended name: Mitochondrial carrier protein CoAc2CuratedAlternative name(s): AtCoAc21 Publication Mitochondrial coenzyme A transporter CoAc2Curated |
Gene namesi | Name:COAC21 Publication Ordered Locus Names:At4g26180Imported ORF Names:F20B18.290Imported, T25K17.6Imported |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G26180 |
TAIRi | locus:2120878, AT4G26180 |
Subcellular locationi
Mitochondrion
- Mitochondrion inner membrane 1 Publication; Multi-pass membrane protein Sequence analysis
Mitochondrion
- mitochondrial inner membrane Source: UniProtKB
- mitochondrion Source: TAIR
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 10 – 30 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Transmembranei | 73 – 93 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Transmembranei | 117 – 137 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Transmembranei | 185 – 205 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Transmembranei | 223 – 243 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Transmembranei | 281 – 301 | Helical; Name=6Sequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Membrane, Mitochondrion, Mitochondrion inner membranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000440986 | 1 – 331 | Mitochondrial carrier protein CoAc2Add BLAST | 331 |
Proteomic databases
ProteomicsDBi | 240911 [F4JU70-1] |
PTM databases
iPTMneti | F4JU70 |
Expressioni
Tissue specificityi
Expressed throughout the plant.1 Publication
Gene expression databases
ExpressionAtlasi | F4JU70, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 15 – 101 | Solcar 1PROSITE-ProRule annotationAdd BLAST | 87 | |
Repeati | 111 – 210 | Solcar 2PROSITE-ProRule annotationAdd BLAST | 100 | |
Repeati | 217 – 308 | Solcar 3PROSITE-ProRule annotationAdd BLAST | 92 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0752, Eukaryota |
OMAi | FYFYETM |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR002167, Graves_DC IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00928, GRAVESDC PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry describes 1 produced by isoform ialternative splicing. AlignAdd to basketNote: A number of isoforms are produced. According to EST sequences.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Isoform 1 (identifier: F4JU70-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MAEGEEKNGI IDSIPLFAKE LIAGGVTGGI AKTAVAPLER IKILFQTRRD
60 70 80 90 100
EFKRIGLVGS INKIGKTEGL MGFYRGNGAS VARIVPYAAL HYMAYEEYRR
110 120 130 140 150
WIIFGFPDTT RGPLLDLVAG SFAGGTAVLF TYPLDLVRTK LAYQVVGSAK
160 170 180 190 200
TQVKAIPVEQ IIYRGIVDCF SRTYRESGAR GLYRGVAPSL YGIFPYAGLK
210 220 230 240 250
FYFYEEMKRH VPPEHKQDIS LKLVCGSVAG LLGQTLTYPL DVVRRQMQVE
260 270 280 290 300
RLYSAVKEET RRGTMQTLFK IAREEGWKQL FSGLSINYLK VVPSVAIGFT
310 320 330
VYDIMKLHLR VPPREEPEAE AVTTRKRKVF T
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1P8B7M7 | A0A1P8B7M7_ARATH | Mitochondrial substrate carrier fam... | CoA Carrier 2 CoAc2, At4g26180, T25K17.6 | 291 | Annotation score: |
Sequence cautioni
The sequence CAB39683 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB79473 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL049171 Genomic DNA No translation available. AL049483 Genomic DNA Translation: CAB39683.1 Sequence problems. AL161564 Genomic DNA Translation: CAB79473.1 Sequence problems. CP002687 Genomic DNA Translation: AEE85167.2 |
PIRi | T04273 |
RefSeqi | NP_001320068.1, NM_001341785.1 [F4JU70-1] |
Genome annotation databases
EnsemblPlantsi | AT4G26180.1; AT4G26180.1; AT4G26180 [F4JU70-1] |
GeneIDi | 828724 |
Gramenei | AT4G26180.1; AT4G26180.1; AT4G26180 [F4JU70-1] |
KEGGi | ath:AT4G26180 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL049171 Genomic DNA No translation available. AL049483 Genomic DNA Translation: CAB39683.1 Sequence problems. AL161564 Genomic DNA Translation: CAB79473.1 Sequence problems. CP002687 Genomic DNA Translation: AEE85167.2 |
PIRi | T04273 |
RefSeqi | NP_001320068.1, NM_001341785.1 [F4JU70-1] |
3D structure databases
AlphaFoldDBi | F4JU70 |
SMRi | F4JU70 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT4G26180.1 |
Protein family/group databases
TCDBi | 2.A.29.12.6, the mitochondrial carrier (mc) family |
PTM databases
iPTMneti | F4JU70 |
Proteomic databases
ProteomicsDBi | 240911 [F4JU70-1] |
Protocols and materials databases
DNASUi | 828724 |
Genome annotation databases
EnsemblPlantsi | AT4G26180.1; AT4G26180.1; AT4G26180 [F4JU70-1] |
GeneIDi | 828724 |
Gramenei | AT4G26180.1; AT4G26180.1; AT4G26180 [F4JU70-1] |
KEGGi | ath:AT4G26180 |
Organism-specific databases
Araporti | AT4G26180 |
TAIRi | locus:2120878, AT4G26180 |
Phylogenomic databases
eggNOGi | KOG0752, Eukaryota |
OMAi | FYFYETM |
Miscellaneous databases
PROi | PR:F4JU70 |
Gene expression databases
ExpressionAtlasi | F4JU70, baseline and differential |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR002167, Graves_DC IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00928, GRAVESDC PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | COAC2_ARATH | |
Accessioni | F4JU70Primary (citable) accession number: F4JU70 Secondary accession number(s): Q9SZI9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 5, 2017 |
Last sequence update: | April 12, 2017 | |
Last modified: | May 25, 2022 | |
This is version 27 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families