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Protein

Transcription factor HHO5

Gene

HHO5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcriptional repressor that functions with ULT1 in a pathway which regulates floral meristem homeostasis and organ number in the flower. Binds specifically to the DNA sequence motif 5'-GTAGATTCCT-3' of WUS promoter, and may be involved in direct regulation of WUS expression. Binds specifically to the DNA sequence motif 5'-AAGAATCTTT-3' found in the promoters of AG and the NAC domain genes CUC1, CUC2 and CUC3, and may be involved in direct regulation of these gene expressions.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi245 – 270H-T-H motifPROSITE-ProRule annotationAdd BLAST26

GO - Molecular functioni

  • DNA-binding transcription factor activity Source: TAIR
  • transcription regulatory region DNA binding Source: TAIR

GO - Biological processi

  • floral organ formation Source: TAIR
  • negative regulation of gene expression Source: TAIR
  • regulation of transcription, DNA-templated Source: TAIR
  • specification of plant organ identity Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionDNA-binding
Biological processFlowering, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor HHO5Curated
Alternative name(s):
MYB-domain transcription factor HHO5Curated
Protein HRS1 HOMOLOG 5Curated
Protein ULT1 INTERACTING FACTOR 11 Publication
Gene namesi
Name:HHO5Curated
Synonyms:UIF11 Publication
Ordered Locus Names:At4g37180Imported
ORF Names:C7A10.180Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G37180
TAIRilocus:2115070 AT4G37180

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Disruption phenotypei

Increased number of sepals and petals in flowers. Loss of organ boundary and identity, producing fused sepals, petaloid stamens and branching stamens fused along the filament.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004395471 – 363Transcription factor HHO5Add BLAST363

Proteomic databases

PaxDbiF4JRB0

Expressioni

Tissue specificityi

Expressed in roots, inflorescence apex, floral primordia, stamen primordia, carpel primordia and ovules.1 Publication

Gene expression databases

ExpressionAtlasiF4JRB0 baseline and differential

Interactioni

Subunit structurei

Interacts with ULT1.1 Publication

Binary interactionsi

Protein-protein interaction databases

IntActiF4JRB0, 38 interactors
STRINGi3702.AT4G37180.2

Structurei

3D structure databases

ProteinModelPortaliF4JRB0
SMRiF4JRB0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini214 – 274HTH myb-typePROSITE-ProRule annotationAdd BLAST61

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi165 – 177Pro-richPROSITE-ProRule annotationAdd BLAST13
Compositional biasi198 – 212His-richPROSITE-ProRule annotationAdd BLAST15
Compositional biasi328 – 339Glu-richPROSITE-ProRule annotationAdd BLAST12

Phylogenomic databases

eggNOGiENOG410IHMD Eukaryota
ENOG410YFA9 LUCA
HOGENOMiHOG000237574
InParanoidiF4JRB0
OMAiSRTEQNH
OrthoDBiEOG09360HM2

Family and domain databases

InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017930 Myb_dom
IPR006447 Myb_dom_plants
IPR001005 SANT/Myb
PfamiView protein in Pfam
PF00249 Myb_DNA-binding, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
TIGRFAMsiTIGR01557 myb_SHAQKYF, 1 hit
PROSITEiView protein in PROSITE
PS51294 HTH_MYB, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: F4JRB0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVQTETDQRM GLNLNLSIYS LPKPLSQFLD EVSRIKDNHS KLSEIDGYVG
60 70 80 90 100
KLEEERNKID VFKRELPLCM LLLNEEIVFL CVAIGALKDE ARKGLSLMAS
110 120 130 140 150
NGKFDDVERA KPETDKKSWM SSAQLWISNP NSQFRSTNEE EEDRCVSQNP
160 170 180 190 200
FQTCNYPNQG GVFMPFNRPP PPPPPAPLSL MTPTSEMMMD YSRIEQSHHH
210 220 230 240 250
HQFNKPSSQS HHIQKKEQRR RWSQELHRKF VDALHRLGGP QVATPKQIRD
260 270 280 290 300
LMKVDGLTND EVKSHLQKYR MHIRKHPLHP TKTLSSSDQP GVLERESQSL
310 320 330 340 350
ISLSRSDSPQ SPLVARGLFS SNVGHSSEED EEEEDEEEEK SDGRSSCRND
360
ETKKKRQVLD LEL
Length:363
Mass (Da):41,679
Last modified:June 28, 2011 - v1
Checksum:i450240FEF3551873
GO
Isoform 2 (identifier: F4JRB0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     76-82: Missing.

Note: No experimental confirmation available.Curated
Show »
Length:356
Mass (Da):40,875
Checksum:iAC9D3A06CAE58F1C
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A178V5G1A0A178V5G1_ARATH
Homeodomain-like superfamily protei...
At4g37180, AXX17_At4g42350
278Annotation score:

Sequence cautioni

The sequence AAB38775 differs from that shown. Sequencing errors.Curated
The sequence CAB16780 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB80384 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti331E → D in BAH19394 (PubMed:19423640).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_05888676 – 82Missing in isoform 2. 7

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62741 mRNA Translation: AAB38775.1 Sequence problems.
Z99707 Genomic DNA Translation: CAB16780.1 Sequence problems.
AL161590 Genomic DNA Translation: CAB80384.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86762.1
CP002687 Genomic DNA Translation: AEE86763.1
AK316664 mRNA Translation: BAH19394.1
BT028985 mRNA Translation: ABI93894.1
AY039841 mRNA Translation: AAK63945.1
PIRiC85439
RefSeqiNP_568018.1, NM_119881.3 [F4JRB0-2]
NP_849513.1, NM_179182.2 [F4JRB0-1]
UniGeneiAt.4657

Genome annotation databases

EnsemblPlantsiAT4G37180.1; AT4G37180.1; AT4G37180 [F4JRB0-2]
AT4G37180.2; AT4G37180.2; AT4G37180 [F4JRB0-1]
GeneIDi829872
GrameneiAT4G37180.1; AT4G37180.1; AT4G37180 [F4JRB0-2]
AT4G37180.2; AT4G37180.2; AT4G37180 [F4JRB0-1]
KEGGiath:AT4G37180

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U62741 mRNA Translation: AAB38775.1 Sequence problems.
Z99707 Genomic DNA Translation: CAB16780.1 Sequence problems.
AL161590 Genomic DNA Translation: CAB80384.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86762.1
CP002687 Genomic DNA Translation: AEE86763.1
AK316664 mRNA Translation: BAH19394.1
BT028985 mRNA Translation: ABI93894.1
AY039841 mRNA Translation: AAK63945.1
PIRiC85439
RefSeqiNP_568018.1, NM_119881.3 [F4JRB0-2]
NP_849513.1, NM_179182.2 [F4JRB0-1]
UniGeneiAt.4657

3D structure databases

ProteinModelPortaliF4JRB0
SMRiF4JRB0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiF4JRB0, 38 interactors
STRINGi3702.AT4G37180.2

Proteomic databases

PaxDbiF4JRB0

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G37180.1; AT4G37180.1; AT4G37180 [F4JRB0-2]
AT4G37180.2; AT4G37180.2; AT4G37180 [F4JRB0-1]
GeneIDi829872
GrameneiAT4G37180.1; AT4G37180.1; AT4G37180 [F4JRB0-2]
AT4G37180.2; AT4G37180.2; AT4G37180 [F4JRB0-1]
KEGGiath:AT4G37180

Organism-specific databases

AraportiAT4G37180
TAIRilocus:2115070 AT4G37180

Phylogenomic databases

eggNOGiENOG410IHMD Eukaryota
ENOG410YFA9 LUCA
HOGENOMiHOG000237574
InParanoidiF4JRB0
OMAiSRTEQNH
OrthoDBiEOG09360HM2

Miscellaneous databases

PROiPR:F4JRB0

Gene expression databases

ExpressionAtlasiF4JRB0 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017930 Myb_dom
IPR006447 Myb_dom_plants
IPR001005 SANT/Myb
PfamiView protein in Pfam
PF00249 Myb_DNA-binding, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
TIGRFAMsiTIGR01557 myb_SHAQKYF, 1 hit
PROSITEiView protein in PROSITE
PS51294 HTH_MYB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiHHO5_ARATH
AccessioniPrimary (citable) accession number: F4JRB0
Secondary accession number(s): B9DF77
, O23168, P92984, Q08A94, Q94BW2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 12, 2017
Last sequence update: June 28, 2011
Last modified: October 10, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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Main funding by: National Institutes of Health

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