UniProtKB - F4IGA5 (NU133_ARATH)
Nuclear pore complex protein NUP133
NUP133
Functioni
GO - Molecular functioni
- structural constituent of nuclear pore Source: GO_Central
GO - Biological processi
- mRNA transport Source: UniProtKB-KW
- nuclear pore distribution Source: GO_Central
- protein import into nucleus Source: GO_Central
- regulation of transcription, DNA-templated Source: GO_Central
- RNA export from nucleus Source: GO_Central
- transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery Source: GO_Central
Keywordsi
Biological process | mRNA transport, Protein transport, Translocation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Nuclear pore complex protein NUP1331 PublicationAlternative name(s): Nucleoporin 1331 Publication Nucleoporin Nup155-like |
Gene namesi | Name:NUP1331 Publication Ordered Locus Names:At2g05120Imported ORF Names:F5G3.2Imported |
Organismi | Arabidopsis thaliana (Mouse-ear cress)Imported |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G05120 |
TAIRi | locus:2051234, AT2G05120 |
Subcellular locationi
Nucleus
- Nucleus envelope 1 Publication
- nuclear pore complex 1 Publication
Nucleus
- nuclear pore outer ring Source: GO_Central
Other locations
- membrane Source: GOC
Keywords - Cellular componenti
Nuclear pore complex, NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000431076 | 1 – 1285 | Nuclear pore complex protein NUP133Add BLAST | 1285 |
Proteomic databases
PaxDbi | F4IGA5 |
PRIDEi | F4IGA5 |
ProteomicsDBi | 249209 [F4IGA5-1] |
PTM databases
iPTMneti | F4IGA5 |
Expressioni
Gene expression databases
ExpressionAtlasi | F4IGA5, baseline and differential |
Genevisiblei | F4IGA5, AT |
Interactioni
Subunit structurei
Part of the nuclear pore complex (NPC). The NPC has an eight-fold symmetrical structure comprising a central transport channel and two rings, the cytoplasmic and nuclear rings, to which eight filaments are attached. The cytoplasmic filaments have loose ends, while the nuclear filaments are joined in a distal ring, forming a nuclear basket. NPCs are highly dynamic in configuration and composition, and can be devided in 3 subcomplexes, the NUP62 subcomplex, the NUP107-160 subcomplex and the NUP93 subcomplex, containing approximately 30 different nucleoporin proteins.
1 PublicationProtein-protein interaction databases
BioGRIDi | 460, 4 interactors |
STRINGi | 3702.AT2G05120.1 |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 281 – 286 | Poly-SerSequence analysis | 6 | |
Compositional biasi | 384 – 387 | Poly-SerSequence analysis | 4 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | ENOG502QSRR, Eukaryota |
InParanoidi | F4IGA5 |
OrthoDBi | 51227at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR007187, Nucleoporin_Nup133/Nup155_C IPR014908, Nucleoporin_Nup133/Nup155_N IPR037624, Nup133-like |
PANTHERi | PTHR13405, PTHR13405, 1 hit |
Pfami | View protein in Pfam PF03177, Nucleoporin_C, 1 hit PF08801, Nucleoporin_N, 1 hit |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MFSPLTKRAK QSSRNEKTPR NRVPPPDSPV TPATQNRNNF ISDRPATGTP
60 70 80 90 100
APWAPRLSVL ARVSPGNNGD KGVDSDQLKP VFVGEFPQLL RDEQSYPGDA
110 120 130 140 150
CVSGGMDKET CLSWFITGSK VFVWSHLTTL PSRKCVVLEL PVVVLVNEES
160 170 180 190 200
GSGLQDGKSW LVNVVSWDTS AGAATRASRS RSPVGVVMCN RKTRAVVYWS
210 220 230 240 250
DIFSGQEAAP AEKARHLIKR QSNGIRSSRA ENSDLNSLIT TAVAAAERLC
260 270 280 290 300
IAIACSSNGE LWQFTCSPTG VKSNQVQLNI SSSSVSEGYP RSLIWRFSQG
310 320 330 340 350
LARESCWEFL MLTDCDIHCF TIEPYPDLTV SEVWQHEIVG TDGDSGIKKD
360 370 380 390 400
IASQKQIWPL DLQVDDQGKV ITVLVATICM DRASSSSYTQ YSLLTLQHKS
410 420 430 440 450
EMRFADGREE KVLEKQGPIQ VIIPKARVED KDFLFSMRLR VGGRPPGSAI
460 470 480 490 500
ILSGDGTATV CYCHGSSTRL YKFDLPYDAG KVLDASVLSS TDEHEYGAWT
510 520 530 540 550
VLTEKAGVWA IPEKAVVLGG VEPPERSLSR KNSSNERSTR DETRVTPYGV
560 570 580 590 600
DRTAGRENSD IQNIEDKGNP KMGFTRQTAR DEESEALLGQ LFEGFLLSGK
610 620 630 640 650
VDGSLEKLSQ SGAFDRDGEA NVFARKSKSI VDTLAKHWTT TRGAEIVAMT
660 670 680 690 700
VISSQLVEKQ QKHENFLHFL ALSKCHEELC SKQRHSLQII LENGEKLAAM
710 720 730 740 750
IQLRELQNMI NQNRSARFGS PQAGSEDQVS CALWDLIQFV GERARRNTVL
760 770 780 790 800
LMDRDNAEVF YSKVSELEEV FYCLNRQLEY IIRADQPLGT QLQRACELSN
810 820 830 840 850
ACVTILQTAL DYKNEHQMWY PPLEGLIPWH SQTVVCNGLW CIASFMLHLL
860 870 880 890 900
TEASRIDISA KSDIYTHLEV LTEVLLEACA GSTFAKLERE EENKGLLNEY
910 920 930 940 950
WTRRDTIFDS LYRQAKEFME AEIQGIRERT EATDEDIFRN RCSNLISIAK
960 970 980 990 1000
RHAGYKIMWK ICYDLNDTGL LRNLMHEGVG PQGGFSYFVF QQLYDMKQFS
1010 1020 1030 1040 1050
KLLRLGEEFQ DELLIFLKRH SDLVWLHQVF LHQFSSASDT LHTLALSQDE
1060 1070 1080 1090 1100
ESMTTVEERT GPEPEDVQPT FADRKRFLNL SKIAYVADKD ADSESKVKRI
1110 1120 1130 1140 1150
EADLNLLKLQ EEITKALPNG EARNRLFRPE ELIETCLNIQ GRWTAIKAFE
1160 1170 1180 1190 1200
VFAWTSSSFR ENHRSLLEEC WRNAADQDDW DRHHQASTNE GWSEEETLQN
1210 1220 1230 1240 1250
LRNTALFQAS KRCYGPTRVN TFDGDFAQVL PLRRENPEDS TSSVEDVLMS
1260 1270 1280
HKDFAEAGKL MLTAIMLGCV EEEGIVAEEF SSPME
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A2H1ZE14 | A0A2H1ZE14_ARATH | Nucleoporin, Nup133/Nup155-like pro... | At2g05120, F5G3.2, F5G3_2 | 975 | Annotation score: |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_057124 | 197 – 210 | Missing in isoform 2. Add BLAST | 14 | |
Alternative sequenceiVSP_057125 | 925 – 975 | Missing in isoform 2. Add BLAST | 51 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007018 Genomic DNA Translation: AAD29053.1 CP002685 Genomic DNA Translation: AEC05897.1 |
PIRi | C84465 |
RefSeqi | NP_001189511.1, NM_001202582.1 [F4IGA5-2] |
Genome annotation databases
EnsemblPlantsi | AT2G05120.2; AT2G05120.2; AT2G05120 [F4IGA5-2] |
GeneIDi | 815060 |
Gramenei | AT2G05120.2; AT2G05120.2; AT2G05120 [F4IGA5-2] |
KEGGi | ath:AT2G05120 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC007018 Genomic DNA Translation: AAD29053.1 CP002685 Genomic DNA Translation: AEC05897.1 |
PIRi | C84465 |
RefSeqi | NP_001189511.1, NM_001202582.1 [F4IGA5-2] |
3D structure databases
SMRi | F4IGA5 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 460, 4 interactors |
STRINGi | 3702.AT2G05120.1 |
PTM databases
iPTMneti | F4IGA5 |
Proteomic databases
PaxDbi | F4IGA5 |
PRIDEi | F4IGA5 |
ProteomicsDBi | 249209 [F4IGA5-1] |
Genome annotation databases
EnsemblPlantsi | AT2G05120.2; AT2G05120.2; AT2G05120 [F4IGA5-2] |
GeneIDi | 815060 |
Gramenei | AT2G05120.2; AT2G05120.2; AT2G05120 [F4IGA5-2] |
KEGGi | ath:AT2G05120 |
Organism-specific databases
Araporti | AT2G05120 |
TAIRi | locus:2051234, AT2G05120 |
Phylogenomic databases
eggNOGi | ENOG502QSRR, Eukaryota |
InParanoidi | F4IGA5 |
OrthoDBi | 51227at2759 |
Miscellaneous databases
PROi | PR:F4IGA5 |
Gene expression databases
ExpressionAtlasi | F4IGA5, baseline and differential |
Genevisiblei | F4IGA5, AT |
Family and domain databases
InterProi | View protein in InterPro IPR007187, Nucleoporin_Nup133/Nup155_C IPR014908, Nucleoporin_Nup133/Nup155_N IPR037624, Nup133-like |
PANTHERi | PTHR13405, PTHR13405, 1 hit |
Pfami | View protein in Pfam PF03177, Nucleoporin_C, 1 hit PF08801, Nucleoporin_N, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | NU133_ARATH | |
Accessioni | F4IGA5Primary (citable) accession number: F4IGA5 Secondary accession number(s): F4IGA4, Q9SJ43 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 26, 2014 |
Last sequence update: | June 28, 2011 | |
Last modified: | December 2, 2020 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families