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Entry version 59 (16 Oct 2019)
Sequence version 1 (28 Jun 2011)
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Protein

DNA polymerase epsilon catalytic subunit B

Gene

POL2B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

DNA polymerase II, which participates in chromosomal DNA replication (By similarity). Involved in the determination of cell fate during plant embryogenesis. Contributes to the flowering time repression.By similarity3 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 1 [4Fe-4S] cluster.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi2015ZincBy similarity1
Metal bindingi2018ZincBy similarity1
Metal bindingi2040ZincBy similarity1
Metal bindingi2045ZincBy similarity1
Metal bindingi2076Iron-sulfur (4Fe-4S)By similarity1
Metal bindingi2079Iron-sulfur (4Fe-4S)By similarity1
Metal bindingi2091Iron-sulfur (4Fe-4S)By similarity1
Metal bindingi2093Iron-sulfur (4Fe-4S)By similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri2015 – 2045CysA-typeBy similarityAdd BLAST31

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase
Biological processDNA replication
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA polymerase epsilon catalytic subunit B (EC:2.7.7.7By similarity)
Alternative name(s):
DNA polymerase 2 b
Short name:
AtPOL2b
DNA polymerase II subunit b
Protein TILTED 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:POL2B
Synonyms:TIL2
Ordered Locus Names:At2g27120
ORF Names:T20P8.17
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT2G27120

The Arabidopsis Information Resource

More...
TAIRi
locus:2059314 AT2G27120

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

No visible effects. When associated with heterozygote POL2A disruption; lethal, with sporophytic embryo-defective with an arrest at the globular stage during embryo development. When associated with esd7-1 mutation of POL2A; very early flowering.3 Publications

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004202411 – 2138DNA polymerase epsilon catalytic subunit BAdd BLAST2138

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F4IFN6

PRoteomics IDEntifications database

More...
PRIDEi
F4IFN6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
F4IFN6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mostly expressed at low levels in inflorescence (floral meristem and flowers until anthesis), and, to a lower extent, in seeds.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F4IFN6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
F4IFN6 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterotetramer.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT2G27120.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F4IFN6

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi1224 – 1231Nuclear localization signal 1By similarity8
Motifi2076 – 2093CysB motifBy similarityAdd BLAST18
Motifi2107 – 2114Nuclear localization signal 2By similarity8

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The DNA polymerase activity domain resides in the N-terminal half of the protein, while the C-terminus is necessary for maintenance of the complex.By similarity
The CysA-type zinc finger is required for PCNA-binding.By similarity
The CysB motif binds 1 4Fe-4S cluster and is required for the formation of polymerase complexes.By similarity

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DNA polymerase type-B family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri2015 – 2045CysA-typeBy similarityAdd BLAST31

Keywords - Domaini

Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1798 Eukaryota
COG0417 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F4IFN6

KEGG Orthology (KO)

More...
KOi
K02324

Database of Orthologous Groups

More...
OrthoDBi
39650at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.132.60, 1 hit
3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR042087 DNA_pol_B_C
IPR013697 DNA_pol_e_suA_C
IPR029703 POL2
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10670 PTHR10670, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08490 DUF1744, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01159 DUF1744, 1 hit
SM00486 POLBc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098 SSF53098, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

F4IFN6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGRRCDRRL NVQKVSAADE LETKLGFGLF SQGETRLGWL LTFASSSWED
60 70 80 90 100
ADTGKTFSCV DLFFVTQDGS SFKTKYKFRP YLYAATKDNM ELEVEAYLRR
110 120 130 140 150
RYERQVADIQ IVHKEDLYLK NHLSGLQKKY LKVSFDTVQQ LVEVKRDLLH
160 170 180 190 200
IVERNLAKFN ALEAYESILS GKREQRPQDC LDSVVDLREY DVPYHVRFAI
210 220 230 240 250
DNDVRSGQWY NVSISSTDVI LEKRTDLLQR AEVRVCAFDI ETVKLPLKFP
260 270 280 290 300
DAEYDQIMMI SYMVDGQGFL ITNRECVGKD IEDLEYTPKP EFEGYFKVTN
310 320 330 340 350
VTNEVELLRK WFSHMQELKP GIYVTYNGDF FDWPFIERRA SHHGIKMNEE
360 370 380 390 400
LGFRCDQNQG ECRAKFVCHL DCFSWVKRDS YLPQGSQGLK AVTKVKLGYD
410 420 430 440 450
PLEVNPEDMV RFAMEKPQTM ASYSVSDAVA TYYLYMTYVH PFVFSLATII
460 470 480 490 500
PMVPDEVLRK GSGTLCEMLL MVEAYKANVV CPNKNQADPE KFYQGKLLES
510 520 530 540 550
ETYIGGHVEC LQSGVFRSDI PTSFKLDASA YQQLIDNLGR DLEYAITVEG
560 570 580 590 600
KMRMDSVSNF DEVKEVIREK LEKLRDDPIR EEGPLIYHLD VAAMYPNIIL
610 620 630 640 650
TNRLQPPSIV TDEVCTACDF NGPEKTCLRK LEWVWRGVTF KGNKSEYYHL
660 670 680 690 700
KKQIESESVD AGANMQSSKP FLDLPKVEQQ SKLKERLKKY CQKAYSRVLD
710 720 730 740 750
KPITEVREAG ICMRENPFYV DTVRSFRDRR YEYKTLNKVW KGKLSEAKAS
760 770 780 790 800
GNLIKIQEAH DMVVVYDSLQ LAHKCILNSF YGYVMRKGAR WYSMEMAGVV
810 820 830 840 850
TYTGAKIIQN ARLLIERIGK PLELDTDGIW CALPGSFPEN FTFKTIDMKK
860 870 880 890 900
FTISYPCVIL NVDVAKNNSN DQYQTLVDPV RKTYNSRSEC SIEFEVDGPY
910 920 930 940 950
KAMIIPASKE EGILIKKRYA VFNHDGTIAE LKGFEMKRRG ELKLIKVFQA
960 970 980 990 1000
ELFDKFLHGS TLEECYSAVA AVANRWLDLL EGQGKDIADS ELLDYISESS
1010 1020 1030 1040 1050
TMSKSLADYG QQKSCAVTTA KRLADFLGDT MVKDKGLRCQ YIVAREPEGT
1060 1070 1080 1090 1100
PVSERAVPVA IFQTDDPEKK FYLQKWCKIS SYTGIRSIID WMYYKQRLHS
1110 1120 1130 1140 1150
AIQKVITIPA AMQKVANPVL RVRHPYWLEK KVCDKFRQGK IVDMFSSANK
1160 1170 1180 1190 1200
DHSTTQDNVV ADIEEFCKEN RPSVKGPKPV ARSFEVDRNH SEGKQQESWD
1210 1220 1230 1240 1250
PEFHDISLQN VDKNVDYQGW LELEKRKWKM TLTNKKKRRY SSSLFGFDLE
1260 1270 1280 1290 1300
QNINKKVCKG RVGVGSYFRR PEEALTSSYL QIIQLVQSPQ SGQFFAWVVV
1310 1320 1330 1340 1350
EGLMLKIPLT IPRVFYINSK ASIAGNFTGK CINKILPHGK PCYNLMEVNI
1360 1370 1380 1390 1400
QEDQFIKESK KLAALLADPE IEGIYETKMP LEFSAICQIG CVCKIEDTAK
1410 1420 1430 1440 1450
HRNTQDGWKL GELHRITTTE CRYLENSIPL VYLYHSTSTG RAVYVLYCHA
1460 1470 1480 1490 1500
SKLMSVVVVN PYGDKELLSS ALERQFRDRC QELSPEPFSW DGILFQVEYV
1510 1520 1530 1540 1550
DHPEAATKFL QKALCEYREE NCGATVAVIE CPDFNTTKEG VKALEDFPCV
1560 1570 1580 1590 1600
RIPFNDDDNS YQPVSWQRPA AKIAVLRCAS AIQWLDRRIA QSRYAHVPLG
1610 1620 1630 1640 1650
NFGRDWLTFT VDIFLSRALR DQQQVLWVSD NGVPDLGDIN NEETFLADET
1660 1670 1680 1690 1700
SLLFPGAYRK VSVELKVHRL AVNALLKSDL VSEMEGGGFL GVNSRGSSLN
1710 1720 1730 1740 1750
DNGSFDENNG CAQAFRVLKQ LIKRLLHDAC NSGNIYADSI LQHLSWWLRS
1760 1770 1780 1790 1800
PSSKLHDPAL HLMLHKVMQK VFALLLTDLR RLGAIIIYAD FSKVIIDTGK
1810 1820 1830 1840 1850
FDLSAAKTYC ESLLTVMGSR DIFKLILLEP VHYWHSLLFM DQHNYAGIRA
1860 1870 1880 1890 1900
TGDEISGNEV TIEPKWSVAR HLPEYIQKDF IIIVATFIFG PWKFALEKKR
1910 1920 1930 1940 1950
GSAESLEAEM VEYLKEQIGT RFISMIVEKI GNIRSHIKDI NVSDASWASG
1960 1970 1980 1990 2000
QAPKGDYTFE FIQIITAVLA LDQNVQQDVL VMRKILLKYI KVKECAAEAE
2010 2020 2030 2040 2050
FIDPGPSFIL PNVACSNCGA YRDLDFCRDS ALLTEKEWSC ADPQCVKIYD
2060 2070 2080 2090 2100
KEQIESSIIQ MVRQRERMYQ LQDLVCNRCN QVKAAHLTEQ CECSGSFRCK
2110 2120 2130
ESGSDFHKRI EIFLDIAKRQ KFRLLEECIS WILFATSC
Length:2,138
Mass (Da):244,993
Last modified:June 28, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDC8C343A54645B23
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8B2B9A0A1P8B2B9_ARATH
DNA polymerase epsilon catalytic su...
TIL2 POL2B, TILTED 2, At2g27120, T20P8.17, T20P8_17
2,139Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8B2E1A0A1P8B2E1_ARATH
DNA polymerase epsilon catalytic su...
TIL2 POL2B, TILTED 2, At2g27120, T20P8.17, T20P8_17
2,141Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC77870 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC005623 Genomic DNA Translation: AAC77870.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC07940.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A84669

NCBI Reference Sequences

More...
RefSeqi
NP_180280.2, NM_128270.3

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G27120.1; AT2G27120.1; AT2G27120

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
817254

Gramene; a comparative resource for plants

More...
Gramenei
AT2G27120.1; AT2G27120.1; AT2G27120

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT2G27120

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005623 Genomic DNA Translation: AAC77870.1 Sequence problems.
CP002685 Genomic DNA Translation: AEC07940.1
PIRiA84669
RefSeqiNP_180280.2, NM_128270.3

3D structure databases

SMRiF4IFN6
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G27120.1

PTM databases

iPTMnetiF4IFN6

Proteomic databases

PaxDbiF4IFN6
PRIDEiF4IFN6

Genome annotation databases

EnsemblPlantsiAT2G27120.1; AT2G27120.1; AT2G27120
GeneIDi817254
GrameneiAT2G27120.1; AT2G27120.1; AT2G27120
KEGGiath:AT2G27120

Organism-specific databases

AraportiAT2G27120
TAIRilocus:2059314 AT2G27120

Phylogenomic databases

eggNOGiKOG1798 Eukaryota
COG0417 LUCA
InParanoidiF4IFN6
KOiK02324
OrthoDBi39650at2759

Miscellaneous databases

Protein Ontology

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PROi
PR:F4IFN6

Gene expression databases

ExpressionAtlasiF4IFN6 baseline and differential
GenevisibleiF4IFN6 AT

Family and domain databases

Gene3Di1.10.132.60, 1 hit
3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR006172 DNA-dir_DNA_pol_B
IPR006133 DNA-dir_DNA_pol_B_exonuc
IPR006134 DNA-dir_DNA_pol_B_multi_dom
IPR042087 DNA_pol_B_C
IPR013697 DNA_pol_e_suA_C
IPR029703 POL2
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PANTHERiPTHR10670 PTHR10670, 1 hit
PfamiView protein in Pfam
PF00136 DNA_pol_B, 1 hit
PF03104 DNA_pol_B_exo1, 1 hit
PF08490 DUF1744, 1 hit
SMARTiView protein in SMART
SM01159 DUF1744, 1 hit
SM00486 POLBc, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDPOE2_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F4IFN6
Secondary accession number(s): Q9ZVC8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2012
Last sequence update: June 28, 2011
Last modified: October 16, 2019
This is version 59 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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