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Entry version 65 (17 Jun 2020)
Sequence version 1 (28 Jun 2011)
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Protein

ATPase family AAA domain-containing protein At1g05910

Gene

At1g05910

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi422 – 429ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ATPase family AAA domain-containing protein At1g05910
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At1g05910
ORF Names:T20M3.19
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G05910

The Arabidopsis Information Resource

More...
TAIRi
locus:2198748 AT1G05910

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004157371 – 1210ATPase family AAA domain-containing protein At1g05910Add BLAST1210

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F4IAE9

PRoteomics IDEntifications database

More...
PRIDEi
F4IAE9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
242985

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
F4IAE9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F4IAE9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
F4IAE9 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT1G05910.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F4IAE9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini910 – 980BromoPROSITE-ProRule annotationAdd BLAST71

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi170 – 227Glu-richAdd BLAST58

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the AAA ATPase family.Curated

Keywords - Domaini

Bromodomain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0732 Eukaryota
COG0464 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007111_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F4IAE9

Identification of Orthologs from Complete Genome Data

More...
OMAi
RPKYFGR

Database of Orthologous Groups

More...
OrthoDBi
443983at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.920.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR041569 AAA_lid_3
IPR003959 ATPase_AAA_core
IPR003960 ATPase_AAA_CS
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00004 AAA, 1 hit
PF17862 AAA_lid_3, 1 hit
PF00439 Bromodomain, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00503 BROMODOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 1 hit
SM00297 BROMO, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47370 SSF47370, 1 hit
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00674 AAA, 1 hit
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F4IAE9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHPKRSSQGD GSVTKPVRTS DRLRRRPKLH GRSYLYYSSP NMLHNRKRNT
60 70 80 90 100
KTRTAASQIA KMLHKGNRPA RASNAAPIAS DLRRSTRKRR ISVNLEDYTD
110 120 130 140 150
SSGAEDEDMM SPAYRTLRRR VHKNFSTSKS RKDMDAELAP RREGLRPRRS
160 170 180 190 200
TTIANKRLKT ESGADQDTSE EKDGQDETEN GNELDDADDG ENEVEAEDEG
210 220 230 240 250
NGEDEGDGED EGEEDGDDDE EGDEEQEGRK RYDLRNRAEV RRMPTGEINK
260 270 280 290 300
QQQPRSPRRV LHQGMGTRVG RDGRRGGSRP HKRHRFTRTD DSDDSLLVDE
310 320 330 340 350
LDQGPAIPWA RGGNRSGAPW LFGGLDTYGS SSLGLNVGAS GWGHQSDGLA
360 370 380 390 400
ALTSGVQTAG PSSKGGADIQ PLQINEDINF DDIGGLSEYI NDLKEMVFFP
410 420 430 440 450
LLYPEFFASY SITPPRGVLL CGPPGTGKTL IARALACAAS KAGQKVSFYM
460 470 480 490 500
RKGADVLSKW VGEAERQLKL LFEEAQRNQP SIIFFDEIDG LAPVRSSKQE
510 520 530 540 550
QIHNSIVSTL LALMDGLDSR GQVVLIGATN RVDAIDGALR RPGRFDREFN
560 570 580 590 600
FSLPGCEARA EILDIHTRKW KHPPTRELKE ELAATCVGYC GADLKALCTE
610 620 630 640 650
AAIRAFREKY PQVYTSDDKY AIDVGLVNVE KSHFVEAMSA ITPAAHRGSV
660 670 680 690 700
VQSRPLSPVV LPCLHRHLLE SMSLISDIFP SSATSSELTK LSILTFGSAI
710 720 730 740 750
PLVYRPRLLL LGGEGVGLDH LGPAILHELE KFPIHSLGLP SLLSDPGAKT
760 770 780 790 800
PEEALVHIFS EARRTTPSIL YIPMFNNWWE NAHEQLRAVF LTLLEELPSN
810 820 830 840 850
LPILLLATSY GELSDMEEQS VFDNRSVYTV DKPSSEDRSL FFDRLIEAAL
860 870 880 890 900
SVISGLNGKP DGPQPLPELP KVPKEPTGPK PAEVKAKVEA EQHALRRLRM
910 920 930 940 950
CLRDVCNRIL YDKRFSAFHF PVTDEDAPNY RSIIQIPMDT ATLLQRVDTG
960 970 980 990 1000
QYLTCTPFLQ DVDLIVRNAK AYNGDDYAGA RIVSRAYELR DVVHGMLSQM
1010 1020 1030 1040 1050
DPALLTYCDK IAAEGGPSLI PDDLSGSILG LAPVVQMGTV TRTSARLRNV
1060 1070 1080 1090 1100
QPEVNLDRDY EGLKKPKKTT DAVSIDSAAD KSQNQDSGQE MPSPDAANPQ
1110 1120 1130 1140 1150
SAAPSPTDGD REDQSEPPSK EASAEDMSGD SCKGPAAKSD KEISSRTESV
1160 1170 1180 1190 1200
KGVFMERTDN YSIPQMERLY TRIMKGVLET LDKGLRDDDN NPKHSILRFL
1210
SEFAQHQANF
Length:1,210
Mass (Da):133,784
Last modified:June 28, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA71F96B291BF677E
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAF29398 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti515D → N in AAO11644 (PubMed:14593172).Curated1
Sequence conflicti515D → N in AAL10476 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC009999 Genomic DNA Translation: AAF29398.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE27917.1
AY056785 mRNA Translation: AAL10476.1
BT002728 mRNA Translation: AAO11644.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B86194

NCBI Reference Sequences

More...
RefSeqi
NP_563753.1, NM_100472.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G05910.1; AT1G05910.1; AT1G05910

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
837101

Gramene; a comparative resource for plants

More...
Gramenei
AT1G05910.1; AT1G05910.1; AT1G05910

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G05910

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009999 Genomic DNA Translation: AAF29398.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE27917.1
AY056785 mRNA Translation: AAL10476.1
BT002728 mRNA Translation: AAO11644.1
PIRiB86194
RefSeqiNP_563753.1, NM_100472.2

3D structure databases

SMRiF4IAE9
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G05910.1

PTM databases

iPTMnetiF4IAE9

Proteomic databases

PaxDbiF4IAE9
PRIDEiF4IAE9
ProteomicsDBi242985

Genome annotation databases

EnsemblPlantsiAT1G05910.1; AT1G05910.1; AT1G05910
GeneIDi837101
GrameneiAT1G05910.1; AT1G05910.1; AT1G05910
KEGGiath:AT1G05910

Organism-specific databases

AraportiAT1G05910
TAIRilocus:2198748 AT1G05910

Phylogenomic databases

eggNOGiKOG0732 Eukaryota
COG0464 LUCA
HOGENOMiCLU_007111_0_0_1
InParanoidiF4IAE9
OMAiRPKYFGR
OrthoDBi443983at2759

Miscellaneous databases

Protein Ontology

More...
PROi
PR:F4IAE9

Gene expression databases

ExpressionAtlasiF4IAE9 baseline and differential
GenevisibleiF4IAE9 AT

Family and domain databases

Gene3Di1.20.920.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR041569 AAA_lid_3
IPR003959 ATPase_AAA_core
IPR003960 ATPase_AAA_CS
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF17862 AAA_lid_3, 1 hit
PF00439 Bromodomain, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00297 BROMO, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
SSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00674 AAA, 1 hit
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiY1591_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F4IAE9
Secondary accession number(s): Q93ZM5, Q9MA34
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 22, 2012
Last sequence update: June 28, 2011
Last modified: June 17, 2020
This is version 65 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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