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Entry version 56 (08 May 2019)
Sequence version 1 (28 Jun 2011)
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Protein
Submitted name:

Tetratricopeptide repeat (TPR)-like superfamily protein

Gene

At1g16480

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • RNA modification Source: GO_Central

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Tetratricopeptide repeat (TPR)-like superfamily proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At1g16480Imported
ORF Names:F3O9.28Imported, F3O9_28Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G16480

The Arabidopsis Information Resource

More...
TAIRi
locus:2032840 AT1G16480

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F4I4G1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F4I4G1 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT1G16480.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F4I4G1

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati22 – 56PPRPROSITE-ProRule annotationAdd BLAST35
Repeati57 – 92PPRPROSITE-ProRule annotationAdd BLAST36
Repeati93 – 123PPRPROSITE-ProRule annotationAdd BLAST31
Repeati124 – 158PPRPROSITE-ProRule annotationAdd BLAST35
Repeati159 – 193PPRPROSITE-ProRule annotationAdd BLAST35
Repeati194 – 224PPRPROSITE-ProRule annotationAdd BLAST31
Repeati225 – 259PPRPROSITE-ProRule annotationAdd BLAST35
Repeati295 – 325PPRPROSITE-ProRule annotationAdd BLAST31
Repeati326 – 360PPRPROSITE-ProRule annotationAdd BLAST35
Repeati396 – 426PPRPROSITE-ProRule annotationAdd BLAST31
Repeati427 – 461PPRPROSITE-ProRule annotationAdd BLAST35
Repeati462 – 497PPRPROSITE-ProRule annotationAdd BLAST36
Repeati498 – 528PPRPROSITE-ProRule annotationAdd BLAST31
Repeati529 – 563PPRPROSITE-ProRule annotationAdd BLAST35
Repeati564 – 598PPRPROSITE-ProRule annotationAdd BLAST35
Repeati599 – 629PPRPROSITE-ProRule annotationAdd BLAST31
Repeati630 – 664PPRPROSITE-ProRule annotationAdd BLAST35
Repeati665 – 700PPRPROSITE-ProRule annotationAdd BLAST36
Repeati701 – 731PPRPROSITE-ProRule annotationAdd BLAST31
Repeati767 – 801PPRPROSITE-ProRule annotationAdd BLAST35
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini804 – 927DYW_deaminaseInterPro annotationAdd BLAST124

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PPR family. PCMP-H subfamily.SAAS annotation

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4197 Eukaryota
ENOG410Z7Z7 LUCA

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F4I4G1

Database of Orthologous Groups

More...
OrthoDBi
1344243at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 8 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032867 DYW_dom
IPR002885 Pentatricopeptide_repeat
IPR011990 TPR-like_helical_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14432 DYW_deaminase, 1 hit
PF01535 PPR, 8 hits
PF13041 PPR_2, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00756 PPR, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51375 PPR, 20 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F4I4G1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYTKFGRVKP ARHLFDIMPV RNEVSWNTMM SGIVRVGLYL EGMEFFRKMC
60 70 80 90 100
DLGIKPSSFV IASLVTACGR SGSMFREGVQ VHGFVAKSGL LSDVYVSTAI
110 120 130 140 150
LHLYGVYGLV SCSRKVFEEM PDRNVVSWTS LMVGYSDKGE PEEVIDIYKG
160 170 180 190 200
MRGEGVGCNE NSMSLVISSC GLLKDESLGR QIIGQVVKSG LESKLAVENS
210 220 230 240 250
LISMLGSMGN VDYANYIFDQ MSERDTISWN SIAAAYAQNG HIEESFRIFS
260 270 280 290 300
LMRRFHDEVN STTVSTLLSV LGHVDHQKWG RGIHGLVVKM GFDSVVCVCN
310 320 330 340 350
TLLRMYAGAG RSVEANLVFK QMPTKDLISW NSLMASFVND GRSLDALGLL
360 370 380 390 400
CSMISSGKSV NYVTFTSALA ACFTPDFFEK GRILHGLVVV SGLFYNQIIG
410 420 430 440 450
NALVSMYGKI GEMSESRRVL LQMPRRDVVA WNALIGGYAE DEDPDKALAA
460 470 480 490 500
FQTMRVEGVS SNYITVVSVL SACLLPGDLL ERGKPLHAYI VSAGFESDEH
510 520 530 540 550
VKNSLITMYA KCGDLSSSQD LFNGLDNRNI ITWNAMLAAN AHHGHGEEVL
560 570 580 590 600
KLVSKMRSFG VSLDQFSFSE GLSAAAKLAV LEEGQQLHGL AVKLGFEHDS
610 620 630 640 650
FIFNAAADMY SKCGEIGEVV KMLPPSVNRS LPSWNILISA LGRHGYFEEV
660 670 680 690 700
CATFHEMLEM GIKPGHVTFV SLLTACSHGG LVDKGLAYYD MIARDFGLEP
710 720 730 740 750
AIEHCICVID LLGRSGRLAE AETFISKMPM KPNDLVWRSL LASCKIHGNL
760 770 780 790 800
DRGRKAAENL SKLEPEDDSV YVLSSNMFAT TGRWEDVENV RKQMGFKNIK
810 820 830 840 850
KKQACSWVKL KDKVSSFGIG DRTHPQTMEI YAKLEDIKKL IKESGYVADT
860 870 880 890 900
SQALQDTDEE QKEHNLWNHS ERLALAYALM STPEGSTVRI FKNLRICSDC
910 920 930
HSVYKFVSRV IGRRIVLRDQ YRFHHFERGL CSCKDYW
Length:937
Mass (Da):104,028
Last modified:June 28, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2A2491A2B4629491
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4I4G0F4I4G0_ARATH
Tetratricopeptide repeat (TPR)-like...
At1g16480, F3O9.28, F3O9_28
928Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP002684 Genomic DNA Translation: AEE29459.1

NCBI Reference Sequences

More...
RefSeqi
NP_173097.2, NM_101513.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G16480.1; AT1G16480.1; AT1G16480

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
838218

Gramene; a comparative resource for plants

More...
Gramenei
AT1G16480.1; AT1G16480.1; AT1G16480

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002684 Genomic DNA Translation: AEE29459.1
RefSeqiNP_173097.2, NM_101513.4

3D structure databases

SMRiF4I4G1
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G16480.1

Proteomic databases

PaxDbiF4I4G1

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G16480.1; AT1G16480.1; AT1G16480
GeneIDi838218
GrameneiAT1G16480.1; AT1G16480.1; AT1G16480

Organism-specific databases

AraportiAT1G16480
TAIRilocus:2032840 AT1G16480

Phylogenomic databases

eggNOGiKOG4197 Eukaryota
ENOG410Z7Z7 LUCA
InParanoidiF4I4G1
OrthoDBi1344243at2759

Gene expression databases

ExpressionAtlasiF4I4G1 baseline and differential

Family and domain databases

Gene3Di1.25.40.10, 8 hits
InterProiView protein in InterPro
IPR032867 DYW_dom
IPR002885 Pentatricopeptide_repeat
IPR011990 TPR-like_helical_dom_sf
PfamiView protein in Pfam
PF14432 DYW_deaminase, 1 hit
PF01535 PPR, 8 hits
PF13041 PPR_2, 2 hits
TIGRFAMsiTIGR00756 PPR, 8 hits
PROSITEiView protein in PROSITE
PS51375 PPR, 20 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF4I4G1_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F4I4G1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: May 8, 2019
This is version 56 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health

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