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UniProtKB - F4I248 (CSCLB_ARATH)
Protein
CSC1-like protein At1g69450
Gene
At1g69450
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Acts as an osmosensitive calcium-permeable cation channel.
By similarityGO - Molecular functioni
- calcium activated cation channel activity Source: GO_Central
Keywordsi
Molecular function | Ion channel |
Biological process | Ion transport, Transport |
Ligand | Calcium |
Names & Taxonomyi
Protein namesi | Recommended name: CSC1-like protein At1g69450 |
Gene namesi | Ordered Locus Names:At1g69450 ORF Names:F10D13_27 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G69450 |
TAIRi | locus:2007126, AT1G69450 |
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 2 – 22 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 89 – 109 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 146 – 166 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 351 – 371 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 403 – 423 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 443 – 463 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 488 – 510 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 553 – 573 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 595 – 615 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 620 – 640 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000429809 | 1 – 711 | CSC1-like protein At1g69450Add BLAST | 711 |
Proteomic databases
PaxDbi | F4I248 |
PRIDEi | F4I248 |
ProteomicsDBi | 220493 |
Expressioni
Gene expression databases
ExpressionAtlasi | F4I248, baseline and differential |
Genevisiblei | F4I248, AT |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1134, Eukaryota |
HOGENOMi | CLU_002458_7_1_1 |
InParanoidi | F4I248 |
Family and domain databases
InterProi | View protein in InterPro IPR045122, Csc1-like IPR032880, Csc1_N IPR027815, PHM7_cyt IPR003864, RSN1_7TM |
PANTHERi | PTHR13018, PTHR13018, 1 hit |
Pfami | View protein in Pfam PF14703, PHM7_cyt, 1 hit PF02714, RSN1_7TM, 1 hit PF13967, RSN1_TM, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F4I248-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLLSALLMSV GINSCLCVLL FILYSVLRKQ PRNYEVFLPR RLANGTYKRR
60 70 80 90 100
RNKVARYIPS LKWIWKSWRP TEKELMESSG LDGVVFMRMI TFSLKVFLFA
110 120 130 140 150
GIIGVFVLLP VNCFGDQLTV IDYADWSANS LDLFSVANLK VRSQWLWVHF
160 170 180 190 200
GAIYLVTVFV CCLLYFEFRY IALKRIEHFY SSKPKPEQFT ILVRNIPSSD
210 220 230 240 250
GSSVSDTVDR FFGENHSSTY FSHVVIHRTS KLRSVVDKAK KLYKEVKHKK
260 270 280 290 300
PVKKTPMRFF SRKDNTEGHY ESVLQEMEQN IRLGQAEVSA PGKEVRAAFV
310 320 330 340 350
SFKSRYGAAT ALHMPQSINP TYWLTEPAPE PHDVHWPFFS ASFMQKWLAK
360 370 380 390 400
ILVVFACLLL TILFLVPVVL VQGLTNLPAL EFMFPFLSLI LSMKVVSQII
410 420 430 440 450
TGYLPSLILQ TSLKVVPPTM EFLSSIQGHI CHSDIQKSAC NKVIWFTIWN
460 470 480 490 500
VFFATVFSGS AFYKLSVILD PKQIPLKLAV AVPAQASFFI AYVVTTGWTD
510 520 530 540 550
TLTELFRVVP FMVSYIKRSF EPSDENEFVV PPMRYHRDTP RVLFFGLLGI
560 570 580 590 600
TYFFLAPLIL PFILLYFILA YIIYRNQFMN VYAPKFDTGG MFWPMIHYTM
610 620 630 640 650
IFSLVLMQAI AIGLFALKKM ELATYLLVPL PVFTLLFNEF CRKRFMPIFT
660 670 680 690 700
DYPAEVLTKR DKEDRNDPTM PEFYNNLVSA YKDPALLPLR FSGSGSRNDS
710
LTSPLLSFSE V
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1P8AP05 | A0A1P8AP05_ARATH | Early-responsive to dehydration str... | At1g69450, F10D13.27, F10D13_27 | 738 | Annotation score: |
Sequence cautioni
The sequence AAG60099 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC073178 Genomic DNA Translation: AAG60099.1 Sequence problems. CP002684 Genomic DNA Translation: AEE34926.1 CP002684 Genomic DNA Translation: AEE34927.1 BX814798 mRNA No translation available. |
RefSeqi | NP_001185356.1, NM_001198427.2 NP_177104.2, NM_105612.2 |
Genome annotation databases
EnsemblPlantsi | AT1G69450.1; AT1G69450.1; AT1G69450 AT1G69450.2; AT1G69450.2; AT1G69450 |
GeneIDi | 843277 |
Gramenei | AT1G69450.1; AT1G69450.1; AT1G69450 AT1G69450.2; AT1G69450.2; AT1G69450 |
KEGGi | ath:AT1G69450 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC073178 Genomic DNA Translation: AAG60099.1 Sequence problems. CP002684 Genomic DNA Translation: AEE34926.1 CP002684 Genomic DNA Translation: AEE34927.1 BX814798 mRNA No translation available. |
RefSeqi | NP_001185356.1, NM_001198427.2 NP_177104.2, NM_105612.2 |
3D structure databases
SMRi | F4I248 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 3702.AT1G69450.2 |
Proteomic databases
PaxDbi | F4I248 |
PRIDEi | F4I248 |
ProteomicsDBi | 220493 |
Genome annotation databases
EnsemblPlantsi | AT1G69450.1; AT1G69450.1; AT1G69450 AT1G69450.2; AT1G69450.2; AT1G69450 |
GeneIDi | 843277 |
Gramenei | AT1G69450.1; AT1G69450.1; AT1G69450 AT1G69450.2; AT1G69450.2; AT1G69450 |
KEGGi | ath:AT1G69450 |
Organism-specific databases
Araporti | AT1G69450 |
TAIRi | locus:2007126, AT1G69450 |
Phylogenomic databases
eggNOGi | KOG1134, Eukaryota |
HOGENOMi | CLU_002458_7_1_1 |
InParanoidi | F4I248 |
Miscellaneous databases
PROi | PR:F4I248 |
Gene expression databases
ExpressionAtlasi | F4I248, baseline and differential |
Genevisiblei | F4I248, AT |
Family and domain databases
InterProi | View protein in InterPro IPR045122, Csc1-like IPR032880, Csc1_N IPR027815, PHM7_cyt IPR003864, RSN1_7TM |
PANTHERi | PTHR13018, PTHR13018, 1 hit |
Pfami | View protein in Pfam PF14703, PHM7_cyt, 1 hit PF02714, RSN1_7TM, 1 hit PF13967, RSN1_TM, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CSCLB_ARATH | |
Accessioni | F4I248Primary (citable) accession number: F4I248 Secondary accession number(s): Q9C792 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 9, 2014 |
Last sequence update: | June 28, 2011 | |
Last modified: | February 23, 2022 | |
This is version 64 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families