Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 61 (02 Jun 2021)
Sequence version 1 (28 Jun 2011)
Previous versions | rss
Add a publicationFeedback
Protein

Protein NETWORKED 2B

Gene

NET2B

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein NETWORKED 2B1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NET2B1 Publication
Ordered Locus Names:At1g09720Imported
ORF Names:F21M12.11Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G09720

The Arabidopsis Information Resource

More...
TAIRi
locus:2024271, AT1G09720

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004318541 – 928Protein NETWORKED 2BAdd BLAST928

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F4I131

PRoteomics IDEntifications database

More...
PRIDEi
F4I131

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
250508

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
F4I131

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F4I131, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
F4I131, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT1G09720.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F4I131

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 90NABPROSITE-ProRule annotationAdd BLAST81

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni108 – 144DisorderedSequence analysisAdd BLAST37
Regioni447 – 472DisorderedSequence analysisAdd BLAST26
Regioni489 – 529DisorderedSequence analysisAdd BLAST41
Regioni620 – 651DisorderedSequence analysisAdd BLAST32

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili207 – 309Sequence analysisAdd BLAST103
Coiled coili360 – 445Sequence analysisAdd BLAST86
Coiled coili547 – 574Sequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi450 – 468Acidic residuesSequence analysisAdd BLAST19
Compositional biasi489 – 508Basic and acidic residuesSequence analysisAdd BLAST20
Compositional biasi621 – 637Polar residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NET family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QQVH, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_004324_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F4I131

Identification of Orthologs from Complete Genome Data

More...
OMAi
FQRVEDQ

Database of Orthologous Groups

More...
OrthoDBi
186795at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011684, NAB

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07765, KIP1, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51774, NAB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F4I131-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLQRAASNAY SWWWASHIRT KQSKWLEHNL QDMEEKVKYT LKIIDGDGDS
60 70 80 90 100
FAKRAEMYYR KRPEIVNFVE EAFRSYRALA ERYDHLSTEL QSANHMIATA
110 120 130 140 150
FPEHVPFPLV DDDDDDDDDN PKKPPKHLHL IPSGTNIPQV PEVPKKEFKS
160 170 180 190 200
QSLMVLSRKE PGVLQSSETS SALVSSGLSR EEALEEIDKI HKGILVLQTE
210 220 230 240 250
KEFVRSSYEQ SYDRYWNLEN EVEEMQKRVC SLQDEFGVGG EIEDGEARTL
260 270 280 290 300
VATAALSSCK ETIAKLEETQ KRFSEDAGIE KERIDTATER CEALKKKFEI
310 320 330 340 350
KVEEQAKKAF HGQESSYESV KESRQIDLNE NLSNVDFAEK IDELVEKVVS
360 370 380 390 400
LETTALSHTA LLKTLRSETN ELQDHIRDVE KDKACLVSDS MDMKKRITVL
410 420 430 440 450
EDELRKVKNL FQRVEDQNKN LHKHLTEANS TAKDLSGKLQ EVKMDEDVEG
460 470 480 490 500
DGLNPEDIQE EDTVEDSDSI SNEREIKNAE EIKEAMVIKQ SRDQESMQEE
510 520 530 540 550
KSETRDSCGG LSETESTCFG TEAEDEERRN WRQLLPADGM EDREKVLLDE
560 570 580 590 600
YSSVLRDYRE VKRKLSEVEK KNRDGFFELA LQLRELKNAV SCEDVDFHFL
610 620 630 640 650
HQKPELPGQG FPHPVERNRA ESVSISHSSN SSFSMPPLPQ RGDLKRASEQ
660 670 680 690 700
EKEDGFKVKF AGISDSLRKK IPTVEEKVRG DIDAVLEENI EFWLRFSTSV
710 720 730 740 750
HQIQKYHTSV QDLKAELSKI ESKQQGNAGS SSNTALASEA KPIYRHLREI
760 770 780 790 800
RTELQLWLEN SAILRDELEG RYATLCNIKD EVSRVTSQSG ATEVSNTEIR
810 820 830 840 850
GYQAAKFHGE ILNMKQENKR VFNELQAGLD RARALRAEVE RVVCKLEENL
860 870 880 890 900
GILDGTATRS LSKRMPSSAG KPRIPLRSFL FGVKLKKYKQ QPKQTSTIFS
910 920
CVSPSPALNK QCSYIIPPAK LPEYVKRS
Length:928
Mass (Da):106,069
Last modified:June 28, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0BDD7B037FAF4904
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAB60728 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC000132 Genomic DNA Translation: AAB60728.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE28484.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B86231

NCBI Reference Sequences

More...
RefSeqi
NP_172443.2, NM_100844.2

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G09720.1; AT1G09720.1; AT1G09720

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
837500

Gramene; a comparative resource for plants

More...
Gramenei
AT1G09720.1; AT1G09720.1; AT1G09720

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G09720

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC000132 Genomic DNA Translation: AAB60728.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE28484.1
PIRiB86231
RefSeqiNP_172443.2, NM_100844.2

3D structure databases

SMRiF4I131
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G09720.1

PTM databases

iPTMnetiF4I131

Proteomic databases

PaxDbiF4I131
PRIDEiF4I131
ProteomicsDBi250508

Genome annotation databases

EnsemblPlantsiAT1G09720.1; AT1G09720.1; AT1G09720
GeneIDi837500
GrameneiAT1G09720.1; AT1G09720.1; AT1G09720
KEGGiath:AT1G09720

Organism-specific databases

AraportiAT1G09720
TAIRilocus:2024271, AT1G09720

Phylogenomic databases

eggNOGiENOG502QQVH, Eukaryota
HOGENOMiCLU_004324_0_0_1
InParanoidiF4I131
OMAiFQRVEDQ
OrthoDBi186795at2759

Miscellaneous databases

Protein Ontology

More...
PROi
PR:F4I131

Gene expression databases

ExpressionAtlasiF4I131, baseline and differential
GenevisibleiF4I131, AT

Family and domain databases

InterProiView protein in InterPro
IPR011684, NAB
PfamiView protein in Pfam
PF07765, KIP1, 1 hit
PROSITEiView protein in PROSITE
PS51774, NAB, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNET2B_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F4I131
Secondary accession number(s): O04494
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 4, 2015
Last sequence update: June 28, 2011
Last modified: June 2, 2021
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again