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Entry version 65 (02 Jun 2021)
Sequence version 1 (28 Jun 2011)
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Protein

Protein NETWORKED 1D

Gene

NET1D

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plant-specific actin binding protein. May be part of a membrane-cytoskeletal adapter complex.

1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin filament binding Source: GO_Central

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein NETWORKED 1D1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NET1D1 Publication
Ordered Locus Names:At1g03080Imported
ORF Names:F10O3.10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G03080

The Arabidopsis Information Resource

More...
TAIRi
locus:2007569, AT1G03080

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004318521 – 1733Protein NETWORKED 1DAdd BLAST1733

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F4HZB5

PRoteomics IDEntifications database

More...
PRIDEi
F4HZB5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
249043

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
F4HZB5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F4HZB5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
F4HZB5, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT1G03080.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F4HZB5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini12 – 92NABPROSITE-ProRule annotationAdd BLAST81

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1456 – 1476DisorderedSequence analysisAdd BLAST21
Regioni1628 – 1656DisorderedSequence analysisAdd BLAST29

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili195 – 816Sequence analysisAdd BLAST622
Coiled coili897 – 931Sequence analysisAdd BLAST35
Coiled coili960 – 1043Sequence analysisAdd BLAST84
Coiled coili1196 – 1386Sequence analysisAdd BLAST191
Coiled coili1553 – 1627Sequence analysisAdd BLAST75
Coiled coili1653 – 1686Sequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1635 – 1656Basic and acidic residuesSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NET family.Curated

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QQ6M, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001229_1_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F4HZB5

Identification of Orthologs from Complete Genome Data

More...
OMAi
SECMRLE

Database of Orthologous Groups

More...
OrthoDBi
60151at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011684, NAB

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07765, KIP1, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51774, NAB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F4HZB5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTAVVNGNSK RYSWWWDSHI SPKNSKWLQE NLTDMDSKVK QMIKVIEEDA
60 70 80 90 100
DSFARRAEMY YKKRPELMKL VEEFYRAYRA LAERYDHATG VIRHAQQTMA
110 120 130 140 150
EAFPNQDPMM FGEESPLGSS TDGFDPQTPD SYPPIRAPVY PDDLRKGAFG
160 170 180 190 200
ISSSHLSTVK RNIAFMEDPQ SVSSGKGFKT AKARKGLNFN NVDGKEINAK
210 220 230 240 250
VLSESERASK AEAEIVALKD ALSKVQAEKE ASLAQFDQNL EKLSNLESEV
260 270 280 290 300
SRAQEDSRVL IERATRAEAE VETLRESLSK VEVEKESSLL QYQQCLQNIA
310 320 330 340 350
DLEDRISLAQ KEAGEVDERA NRAEAETLAL KQSLVSSETD KEAALVQYQQ
360 370 380 390 400
CLKTISNLEE RLHKAEEDSR LTNQRAENAE GEVESLKQKV SKLIEENEAY
410 420 430 440 450
ELQYQQCLDT IADLKLKLFH AQEETQRLSR EIEDGVAKLK FAEEKCVVLE
460 470 480 490 500
RSNQNLHSEL DGLLEKLGNQ SHELTEKQKE LGRLWTCVQE ENLRFMEAET
510 520 530 540 550
AFQTLQQLHS QSQEELSTLA LELQNRSQIL KDMEARNNGL QEEVQEAKDQ
560 570 580 590 600
SKSLNELNLS SAASIKSLQE EVSKLRETIQ KLEAEVELRV DQRNALQQEI
610 620 630 640 650
YCLKEELSQI GKKHQSMVEQ VELVGLHPES FGSSVKELQE ENSKLKEIRE
660 670 680 690 700
RESIEKTALI EKLEMMEKLV QKNLLLENSI SDLNAELETI RGKLKTLEEA
710 720 730 740 750
SMSLAEEKSG LHSEKDMLIS RLQSATENSK KLSEENMVLE NSLFNANVEL
760 770 780 790 800
EELKSKLKSL EESCHLLNDD KTTLTSERES LLSHIDTMRK RIEDLEKEHA
810 820 830 840 850
ELKVKVLELA TERESSLQKI EELGVSLNAK DCEYASFVQF SESRMNGMES
860 870 880 890 900
TIHHLQDENQ CRVREYQVEL DRAHDAHIEI IVLQKCLQDW LEKSSSLIAE
910 920 930 940 950
NQDIKEASKL LEKLVSELEE ENIGKQVQID SSINCIKILR TGIYQVLMKL
960 970 980 990 1000
EIIPGIGSGD ENSRDQRNMH DILNRLEDMQ TMLLSIRDEN QHSAIENLVL
1010 1020 1030 1040 1050
IEFLRQLKSE AVGIETEKKI LEEELESQCQ QLSFSRDETQ KLIFVNGELT
1060 1070 1080 1090 1100
TKVNQGVNRE KVLMVEIEDF HRQVLQLRDD YTILQGDNNK TLDEKAYLTK
1110 1120 1130 1140 1150
STLQLEEEKC KLEDDISLLL SETIYQSNLI ILLEDVILEK LSGAMKLNED
1160 1170 1180 1190 1200
LDRLSIVKCK LEEEVRELGD KLKSADIANF QLQVVLEKSN AELLSARSAN
1210 1220 1230 1240 1250
VHLEHEIANV KVQKEKELLE AMLMISIMQN EKSELSKAVE GLECRYKEAK
1260 1270 1280 1290 1300
AIEEDRDKQV LRLRGDYDEQ VKKNSHSNEA NLKLEADLMN LLMELEEIKV
1310 1320 1330 1340 1350
EKENLNQELF TERNEIELWE SQSATLFGEL QISAVHETLL EGLTNELVEA
1360 1370 1380 1390 1400
CKNLESRSTL KDREIEQLKG RVNNLEDANK GQNDLMCKYA QAIFLLKESI
1410 1420 1430 1440 1450
QSLEKHAMLH EFENGPATET ASLVDNSDGF LEIQELHLRI KAIEEAITKK
1460 1470 1480 1490 1500
LAMEELKTSS ARRSRRRNGS LRKQNHEIYS EETEMITKDI VLDQVSDCSS
1510 1520 1530 1540 1550
YGISTRDILK IEDDHSLEAK SQNPPKGKSL SEESLVVDKL EISDRFTDPN
1560 1570 1580 1590 1600
KDANKRKVLE RLNSDLQKLS NLHVAVEDLK IKVETEEKDE KGKENEYETI
1610 1620 1630 1640 1650
KGQINEAEEA LEKLLSINRK LVTKVQNGFE RSDGSKSSMD LDENESSRRR
1660 1670 1680 1690 1700
RISEQARRGS EKIGRLQLEI QRLQFLLLKL EGDREDRAKA KISDSKTRIL
1710 1720 1730
LRDYIYSGVR GERRKRIKKR FAFCGCVQPP PSP
Length:1,733
Mass (Da):198,550
Last modified:June 28, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9DE4EFFF611A7812
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD25801 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC006550 Genomic DNA Translation: AAD25801.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE27526.1
CP002684 Genomic DNA Translation: ANM59941.1
CP002684 Genomic DNA Translation: ANM59942.1

Protein sequence database of the Protein Information Resource

More...
PIRi
F86161

NCBI Reference Sequences

More...
RefSeqi
NP_001322258.1, NM_001331386.1
NP_001322259.1, NM_001331385.1
NP_171807.2, NM_100190.4

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G03080.1; AT1G03080.1; AT1G03080
AT1G03080.2; AT1G03080.2; AT1G03080
AT1G03080.3; AT1G03080.3; AT1G03080

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
838350

Gramene; a comparative resource for plants

More...
Gramenei
AT1G03080.1; AT1G03080.1; AT1G03080
AT1G03080.2; AT1G03080.2; AT1G03080
AT1G03080.3; AT1G03080.3; AT1G03080

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G03080

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006550 Genomic DNA Translation: AAD25801.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE27526.1
CP002684 Genomic DNA Translation: ANM59941.1
CP002684 Genomic DNA Translation: ANM59942.1
PIRiF86161
RefSeqiNP_001322258.1, NM_001331386.1
NP_001322259.1, NM_001331385.1
NP_171807.2, NM_100190.4

3D structure databases

SMRiF4HZB5
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G03080.1

PTM databases

iPTMnetiF4HZB5

Proteomic databases

PaxDbiF4HZB5
PRIDEiF4HZB5
ProteomicsDBi249043

Genome annotation databases

EnsemblPlantsiAT1G03080.1; AT1G03080.1; AT1G03080
AT1G03080.2; AT1G03080.2; AT1G03080
AT1G03080.3; AT1G03080.3; AT1G03080
GeneIDi838350
GrameneiAT1G03080.1; AT1G03080.1; AT1G03080
AT1G03080.2; AT1G03080.2; AT1G03080
AT1G03080.3; AT1G03080.3; AT1G03080
KEGGiath:AT1G03080

Organism-specific databases

AraportiAT1G03080
TAIRilocus:2007569, AT1G03080

Phylogenomic databases

eggNOGiENOG502QQ6M, Eukaryota
HOGENOMiCLU_001229_1_1_1
InParanoidiF4HZB5
OMAiSECMRLE
OrthoDBi60151at2759

Miscellaneous databases

Protein Ontology

More...
PROi
PR:F4HZB5

Gene expression databases

ExpressionAtlasiF4HZB5, baseline and differential
GenevisibleiF4HZB5, AT

Family and domain databases

InterProiView protein in InterPro
IPR011684, NAB
PfamiView protein in Pfam
PF07765, KIP1, 1 hit
PROSITEiView protein in PROSITE
PS51774, NAB, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNET1D_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F4HZB5
Secondary accession number(s): Q9SA62
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 4, 2015
Last sequence update: June 28, 2011
Last modified: June 2, 2021
This is version 65 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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