Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Metal-dependent carboxypeptidase

Gene

PNA2_1108

Organism
Pyrococcus sp. (strain NA2)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.UniRule annotation

Catalytic activityi

Release of a C-terminal amino acid with broad specificity, except for -Pro.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi268Zinc; catalyticUniRule annotation1
Metal bindingi272Zinc; catalyticUniRule annotation1
Metal bindingi298Zinc; catalyticUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciPSP342949:G1GX4-1146-MONOMER

Protein family/group databases

MEROPSiM32.002

Names & Taxonomyi

Protein namesi
Recommended name:
Metal-dependent carboxypeptidaseUniRule annotation (EC:3.4.17.19UniRule annotation)
Gene namesi
Ordered Locus Names:PNA2_1108Imported
OrganismiPyrococcus sp. (strain NA2)Imported
Taxonomic identifieri342949 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000008293 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi342949.PNA2_1108

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M32 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04247 Archaea
COG2317 LUCA
KOiK01299
OMAiEFGHALY
OrthoDBiPOG093Z01FT

Family and domain databases

CDDicd06460 M32_Taq, 1 hit
InterProiView protein in InterPro
IPR001333 Peptidase_M32_Taq
PANTHERiPTHR34217 PTHR34217, 1 hit
PfamiView protein in Pfam
PF02074 Peptidase_M32, 1 hit
PIRSFiPIRSF006615 Zn_crbxpep_Taq, 1 hit
PRINTSiPR00998 CRBOXYPTASET

Sequencei

Sequence statusi: Complete.

F4HN20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVFKNETIK EILQKYRRIW ALGHAQSVLG WDLEVNMPKE GIMERSVAQG
60 70 80 90 100
ELSVLSQELL LRPEFVELVE KAKGIEDLNE YERGVVRVLD RQIRIMKSFP
110 120 130 140 150
PEFLREVSET TSMATKAWEE AKAKDDFSKF EPWLDKIISL AKKAADYLGY
160 170 180 190 200
EEEPYDALLD LYEEGLRTRD VERMFSTLEK ELRPLLEKIL EEGKVPREHP
210 220 230 240 250
LEKEKYEKEW MEKVNIWVLE KFGFPLGVRA RLDVSAHPFT TEFGIRDVRI
260 270 280 290 300
TTRYEGFDFR RTLLSTIHEF GHALYELQQD ERFMFTPIAG GVSLGVHESQ
310 320 330 340 350
SRFWENIIGR SREFVELIYP VLKENLPFLD GYSEEDVYLY FNIVRPDFIR
360 370 380 390 400
TEADVVTYNF HILLRFKLER LMVSEEVKAK DLPEMWNEEM ERLLGIRPKT
410 420 430 440 450
YREGILQDIH WAHGSIGYFP TYSIGTILSA QLYYHIKKDI KDFEEKVRQG
460 470 480 490
DFEPIKAWLR EKIHRWGSIY PPKELIRRAI GEDMDAEYFV KWIRERYL
Length:498
Mass (Da):59,210
Last modified:June 28, 2011 - v1
Checksum:iD921E80F3B293D68
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002670 Genomic DNA Translation: AEC52024.1
RefSeqiWP_013748578.1, NC_015474.1

Genome annotation databases

EnsemblBacteriaiAEC52024; AEC52024; PNA2_1108
GeneIDi10554583
KEGGipyn:PNA2_1108
PATRICifig|342949.8.peg.1112

Similar proteinsi

Entry informationi

Entry nameiF4HN20_PYRSN
AccessioniPrimary (citable) accession number: F4HN20
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: April 25, 2018
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health