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Protein

Guanylate kinase

Gene

gmk

Organism
Francisella cf. novicida (strain 3523)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 17ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciFCF676032:G1GSW-651-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:FN3523_0642Imported
OrganismiFrancisella cf. novicida (strain 3523)Imported
Taxonomic identifieri676032 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaThiotrichalesFrancisellaceaeFrancisella
Proteomesi
  • UP000008303 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi676032.FN3523_0642

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 185Guanylate kinase-likeInterPro annotationAdd BLAST183

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

F4BK05-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNYIFIVSA PSGAGKSSLL KAFLATDIGK DKFAVATSHT TREPRVGEIN
60 70 80 90 100
GREYHFVTVA EFELLLSKDG FIEYAKVFKN YYGTSKAEID RLLAAGKNII
110 120 130 140 150
LEIDWQGAQQ TRAIYGDRAK SIFILPPSLD ELRNRLEKRN TDSKETIDYR
160 170 180 190
MEQAQSEISH ANEYDCQLVN DDFSQSLEQL CKYFEENIQS
Length:190
Mass (Da):21,637
Last modified:June 28, 2011 - v1
Checksum:iFBC0C583074E2A97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002558 Genomic DNA Translation: AEB28499.1
RefSeqiWP_014547952.1, NC_017449.1

Genome annotation databases

EnsemblBacteriaiAEB28499; AEB28499; FN3523_0642
KEGGifcn:FN3523_0642
PATRICifig|676032.3.peg.643

Similar proteinsi

Entry informationi

Entry nameiF4BK05_FRACN
AccessioniPrimary (citable) accession number: F4BK05
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: March 28, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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