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Protein

ATP synthase subunit alpha

Gene

atpA

Organism
Streptomyces sp. Tu6071
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.UniRule annotation

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei404Required for activityUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi203 – 210ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
Biological processATP synthesis, Hydrogen ion transportUniRule annotation, Ion transport, Transport
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alphaUniRule annotation (EC:3.6.3.14UniRule annotation)
Alternative name(s):
ATP synthase F1 sector subunit alphaUniRule annotation
F-ATPase subunit alphaUniRule annotation
Gene namesi
Name:atpAUniRule annotation
ORF Names:STTU_1898Imported
OrganismiStreptomyces sp. Tu6071Imported
Taxonomic identifieri355249 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000003955 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, CF(1)UniRule annotation, Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 126ATP-synt_ab_NInterPro annotationAdd BLAST67
Domaini183 – 406ATP-synt_abInterPro annotationAdd BLAST224
Domaini413 – 538ATP-synt_ab_CInterPro annotationAdd BLAST126

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

F3Z5W3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRPQDEEVL GGSPRNPQRL RAQQGEQGTQ MAELTIRPEE IRDALENFVQ
60 70 80 90 100
SYKPDAASRE EVGTVTTAGD GIARIEGLPS AMANELLKFE DGTLGLALNL
110 120 130 140 150
EEREIGAIVL GEFSGVEEGQ PVTRTGEVLS VGVGDGYLGR VVDPLGNPID
160 170 180 190 200
GLGEIATSGR RALELQAPTV MQRKSVHEPM ETGYKAVDAM TPIGRGQRQL
210 220 230 240 250
IIGDRQTGKT ALAVDTIINQ RGNWESGDPK KQVRCIYVAI GQKGSTIASV
260 270 280 290 300
RGALEEAGAL EYTTIVASPA SDPAGFKYLA PYTGSAIGQH WMYEGKHVLI
310 320 330 340 350
IFDDLSKQAD AYRAVSLLLR RPPGREAYPG DVFYLHSRLL ERCAKLSDDL
360 370 380 390 400
GAGSMTGLPI VETKANDVSA FIPTNVISIT DGQCFLESDL FNAGQRPALN
410 420 430 440 450
VGISVSRVGG SAQHKAMKQV SGRLRLDLAQ YRELESFAAF GSDLDAASKA
460 470 480 490 500
QLGRGQRLVE LLKQDQYQPM ATEDQVVSVW SATTGLMDEV PVADIRRFES
510 520 530 540 550
ELLGWLHQTR QPLMTSIKEG GKMSDDTLTA VGDAVKDFKK QFQTSDGQLL
560
GDDASATAAK
Length:560
Mass (Da):60,336
Last modified:June 28, 2011 - v1
Checksum:iDD0741704BF5D096
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM001165 Genomic DNA Translation: EGJ74687.1

Genome annotation databases

EnsemblBacteriaiEGJ74687; EGJ74687; STTU_1898

Similar proteinsi

Entry informationi

Entry nameiF3Z5W3_9ACTN
AccessioniPrimary (citable) accession number: F3Z5W3
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: July 18, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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