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Protein

ATP synthase subunit alpha

Gene

atpA

Organism
Streptomyces griseoaurantiacus M045
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei399Required for activityUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi198 – 205ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
Biological processATP synthesis, Hydrogen ion transportUniRule annotation, Ion transport, Transport
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alphaUniRule annotation (EC:3.6.3.14UniRule annotation)
Alternative name(s):
ATP synthase F1 sector subunit alphaUniRule annotation
F-ATPase subunit alphaUniRule annotation
Gene namesi
Name:atpAUniRule annotation
ORF Names:SGM_4630Imported
OrganismiStreptomyces griseoaurantiacus M045Imported
Taxonomic identifieri996637 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
Proteomesi
  • UP000003022 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cell membrane UniRule annotation; Peripheral membrane protein UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, CF(1)UniRule annotation, Membrane

Interactioni

Protein-protein interaction databases

STRINGi996637.SGM_4630

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 121ATP-synt_ab_NInterPro annotationAdd BLAST67
Domaini178 – 401ATP-synt_abInterPro annotationAdd BLAST224
Domaini408 – 533ATP-synt_ab_CInterPro annotationAdd BLAST126

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDG Bacteria
COG0056 LUCA
OrthoDBiPOG091H01QH

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

F3NNB6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGVRSLENP PKVKLRAQQG EQGTQMAELT IRPEEIRDAL ENFVQSYQPD
60 70 80 90 100
AASREEVGTV TLAGDGIAKV EGLPSAMANE LLKFEDGTLG LALNLEEREI
110 120 130 140 150
GCVVLGEFSG IEEGQPVTRT GEVLSVAVGE GYLGRVVDPL GNPIDGLGEI
160 170 180 190 200
ETSGRRALEL QAPGVMARKS VHEPMETGYK AVDAMTPVGR GQRQLIIGDR
210 220 230 240 250
QTGKTALAVD TIINQRDNWR SGDPKKQVRC VYVAIGQKGS TIASVRSALE
260 270 280 290 300
ESGALEYTTI VAAPASDPAG FKYLAPYTGS AIGQQWMYEG KHVLIIFDDL
310 320 330 340 350
SKQADAYRAV SLLLRRPPGR EAYPGDVFYL HSRLLERCAK LSDDLGAGSM
360 370 380 390 400
TGLPIVETKA NDVSAFIPTN VISITDGQCF LESDLFNAGQ RPALNVGISV
410 420 430 440 450
SRVGGSAQHK AMKQVSGRLR LDLAQYRELE AFAAFGSDLD AASKSQLERG
460 470 480 490 500
QRLVELLKQP QYQPMPTEDQ VVSVWAGTTG KMDDVPVTDI RRFEKELLEH
510 520 530 540 550
LHRKEQGLMT SIKEGGKMSD DTLQAVGDAI AEFKKQFETS DGKLLGEDAP

SAAK
Length:554
Mass (Da):59,861
Last modified:June 28, 2011 - v1
Checksum:i355F6ED0D7B858FA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEYX01000041 Genomic DNA Translation: EGG45302.1

Genome annotation databases

EnsemblBacteriaiEGG45302; EGG45302; SGM_4630

Similar proteinsi

Entry informationi

Entry nameiF3NNB6_9ACTN
AccessioniPrimary (citable) accession number: F3NNB6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 28, 2011
Last sequence update: June 28, 2011
Last modified: March 28, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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