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Protein
Submitted name:

Serine protease inhibitor A3G

Gene

Serpina3g

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-MMU-114608 Platelet degranulation
R-MMU-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Submitted name:
Serine protease inhibitor A3GImported
Gene namesi
Name:Serpina3gImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:105046 Serpina3g

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiF2Z405
PeptideAtlasiF2Z405
PRIDEiF2Z405

Expressioni

Gene expression databases

BgeeiENSMUSG00000041481 Expressed in 99 organ(s), highest expression level in spleen
ExpressionAtlasiF2Z405 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF2Z405
SMRiF2Z405
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 215SERPINInterPro annotationAdd BLAST215

Sequence similaritiesi

Belongs to the serpin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839
OMAiKPRMIHE
OrthoDBiEOG091G0ION
TreeFamiTF343201

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

F2Z405-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVLVNYIYFK GKWKNPFDPN DTFKSEFYLD EKRSVIVSMM KTGYLTTPYF
60 70 80 90 100
RDEELSCTVV ELKYTGNASA MFILPDQGRM QQVEASLQPE TLRKWKNSLK
110 120 130 140 150
PRMIHELRLP KFSISTDYSL EHILPELGIR EVFSTQADLS AITGTKDLRV
160 170 180 190 200
SQVVHKAVLD VAETGTEAAA ATGMAGVGCC AVFDFLEIFF NRPFLMIISD
210 220 230 240
TKAHIALFMA KVTNPERSMN FPNGEGASSQ RLESKRLCFG DPLCLIGQ
Length:248
Mass (Da):27,947
Last modified:May 31, 2011 - v1
Checksum:iE1BF78704118A28A
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5I2A0SPA3G_MOUSE
Serine protease inhibitor A3G
Serpina3g Spi2A
440Annotation score:
E9Q499E9Q499_MOUSE
Serine protease inhibitor A3G
Serpina3g
100Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC142112 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMUST00000043315; ENSMUSP00000041250; ENSMUSG00000041481

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC142112 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF2Z405
SMRiF2Z405
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiF2Z405
PeptideAtlasiF2Z405
PRIDEiF2Z405

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000043315; ENSMUSP00000041250; ENSMUSG00000041481

Organism-specific databases

MGIiMGI:105046 Serpina3g

Phylogenomic databases

eggNOGiKOG2392 Eukaryota
COG4826 LUCA
GeneTreeiENSGT00760000118839
OMAiKPRMIHE
OrthoDBiEOG091G0ION
TreeFamiTF343201

Enzyme and pathway databases

ReactomeiR-MMU-114608 Platelet degranulation
R-MMU-6798695 Neutrophil degranulation

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000041481 Expressed in 99 organ(s), highest expression level in spleen
ExpressionAtlasiF2Z405 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
PANTHERiPTHR11461 PTHR11461, 1 hit
PfamiView protein in Pfam
PF00079 Serpin, 1 hit
SMARTiView protein in SMART
SM00093 SERPIN, 1 hit
SUPFAMiSSF56574 SSF56574, 1 hit
PROSITEiView protein in PROSITE
PS00284 SERPIN, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF2Z405_MOUSE
AccessioniPrimary (citable) accession number: F2Z405
Entry historyiIntegrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: September 12, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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