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Protein
Submitted name:

Nuclear receptor subfamily 2, group F, member 1

Gene

Nr2f1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-383280 Nuclear Receptor transcription pathway

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 2, group F, member 1Imported
Gene namesi
Name:Nr2f1Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi621682 Nr2f1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiF2Z3S9
PRIDEiF2Z3S9

Expressioni

Gene expression databases

BgeeiENSRNOG00000014795 Expressed in 9 organ(s), highest expression level in brain
ExpressionAtlasiF2Z3S9 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000020044

Structurei

3D structure databases

ProteinModelPortaliF2Z3S9
SMRiF2Z3S9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini80 – 155Nuclear receptorInterPro annotationAdd BLAST76
Domaini181 – 407NR LBDInterPro annotationAdd BLAST227

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118948
InParanoidiF2Z3S9
OMAiGDKGQSQ
OrthoDBiEOG091G0YX6
TreeFamiTF352097

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR003068 COUP_TF
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01282 COUPTNFACTOR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F2Z3S9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAMVVSSWRD PQDDVAGGNP GGPNPAAQAA RGGGGGEQQQ AGSGAPHTPQ
60 70 80 90 100
TPGQPGAPAT PGTAGDKGQG PPGSGQSQQH IECVVCGDKS SGKHYGQFTC
110 120 130 140 150
EGCKSFFKRS VRRNLTYTCR ANRNCPIDQH HRNQCQYCRL KKCLKVGMRR
160 170 180 190 200
EAVQRGRMPP TQPNPGQYAL TNGDPLNGHC YLSGYISLLL RAEPYPTSRY
210 220 230 240 250
GSQCMQPNNI MGIENICELA ARLLFSAVEW ARNIPFFPDL QITDQVSLLR
260 270 280 290 300
LTWSELFVLN AAQCSMPLHV APLLAAAGLH ASPMSADRVV AFMDHIRIFQ
310 320 330 340 350
EQVEKLKALH VDSAEYSCLK AIVLFTSDAC GLSDAAHIES LQEKSQCALE
360 370 380 390 400
EYVRSQYPNQ PSRFGKLLLR LPSLRTVSSS VIEQLFFVRL VGKTPIETLI
410 420
RDMLLSGSSF NWPYMSIQCS
Length:420
Mass (Da):45,899
Last modified:May 31, 2011 - v1
Checksum:iB360CADBAB312908
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1W2Q6N8A0A1W2Q6N8_RAT
Nuclear receptor subfamily 2, group...
Nr2f1
273Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC098504 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSRNOT00000020044; ENSRNOP00000020044; ENSRNOG00000014795

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC098504 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF2Z3S9
SMRiF2Z3S9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000020044

Proteomic databases

PaxDbiF2Z3S9
PRIDEiF2Z3S9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000020044; ENSRNOP00000020044; ENSRNOG00000014795

Organism-specific databases

RGDi621682 Nr2f1

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
GeneTreeiENSGT00760000118948
InParanoidiF2Z3S9
OMAiGDKGQSQ
OrthoDBiEOG091G0YX6
TreeFamiTF352097

Enzyme and pathway databases

ReactomeiR-RNO-383280 Nuclear Receptor transcription pathway

Gene expression databases

BgeeiENSRNOG00000014795 Expressed in 9 organ(s), highest expression level in brain
ExpressionAtlasiF2Z3S9 baseline and differential

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR003068 COUP_TF
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR01282 COUPTNFACTOR
PR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF2Z3S9_RAT
AccessioniPrimary (citable) accession number: F2Z3S9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 31, 2011
Last sequence update: May 31, 2011
Last modified: November 7, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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