UniProtKB - F2Z2P2 (F2Z2P2_HUMAN)
Protein
Submitted name:
Dual-specificity protein phosphatase 18
Gene
DUSP18
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- MAP kinase tyrosine/serine/threonine phosphatase activity Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Dual-specificity protein phosphatase 18Imported |
Gene namesi | Name:DUSP18Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000167065.13 |
HGNCi | HGNC:18484, DUSP18 |
Subcellular locationi
Nucleus
- nucleoplasm Source: HPA
Expressioni
Gene expression databases
Bgeei | ENSG00000167065, Expressed in secondary oocyte and 181 other tissues |
ExpressionAtlasi | F2Z2P2, baseline and differential |
Family & Domainsi
Phylogenomic databases
GeneTreei | ENSGT00940000161186 |
HOGENOMi | CLU_2084045_0_0_1 |
Family and domain databases
Gene3Di | 3.90.190.10, 1 hit |
InterProi | View protein in InterPro IPR020420, Atypical_DUSP_subfamB IPR029021, Prot-tyrosine_phosphatase-like |
PRINTSi | PR01910, ADSPHPHTASEB |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
F2Z2P2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTAPSCAFPV QFRQPSVSGL SQITKSLYIS NGVAANNKLM LSSNQITMVI
60 70 80 90 100
NVSVERGDEA GPYFAALCCW CEPLSCPVPR LPHEVPRHVP AGRPHVDQVM
110
PAHHPTQQRL LGAAHPL
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8NEJ0 | DUS18_HUMAN | Dual specificity protein phosphatas... | DUSP18 LMWDSP20 | 188 | Annotation score: | ||
F8VX42 | F8VX42_HUMAN | Dual-specificity protein phosphatas... | DUSP18 | 163 | Annotation score: | ||
C9JEE9 | C9JEE9_HUMAN | Dual-specificity protein phosphatas... | DUSP18 | 11 | Annotation score: | ||
H7C401 | H7C401_HUMAN | Dual-specificity protein phosphatas... | DUSP18 | 23 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC003072 Genomic DNA No translation available. AC005006 Genomic DNA No translation available. |
RefSeqi | NP_001291725.1, NM_001304796.1 |
Genome annotation databases
Ensembli | ENST00000403268; ENSP00000384946; ENSG00000167065 |
GeneIDi | 150290 |
UCSCi | uc062dfk.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC003072 Genomic DNA No translation available. AC005006 Genomic DNA No translation available. |
RefSeqi | NP_001291725.1, NM_001304796.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PRIDEi | F2Z2P2 |
ProteomicsDBi | 23768 |
Protocols and materials databases
Antibodypediai | 24819, 40 antibodies |
Genome annotation databases
Ensembli | ENST00000403268; ENSP00000384946; ENSG00000167065 |
GeneIDi | 150290 |
UCSCi | uc062dfk.1, human |
Organism-specific databases
CTDi | 150290 |
EuPathDBi | HostDB:ENSG00000167065.13 |
HGNCi | HGNC:18484, DUSP18 |
OpenTargetsi | ENSG00000167065 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000161186 |
HOGENOMi | CLU_2084045_0_0_1 |
Miscellaneous databases
BioGRID-ORCSi | 150290, 2 hits in 843 CRISPR screens |
ChiTaRSi | DUSP18, human |
GenomeRNAii | 150290 |
Gene expression databases
Bgeei | ENSG00000167065, Expressed in secondary oocyte and 181 other tissues |
ExpressionAtlasi | F2Z2P2, baseline and differential |
Family and domain databases
Gene3Di | 3.90.190.10, 1 hit |
InterProi | View protein in InterPro IPR020420, Atypical_DUSP_subfamB IPR029021, Prot-tyrosine_phosphatase-like |
PRINTSi | PR01910, ADSPHPHTASEB |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F2Z2P2_HUMAN | |
Accessioni | F2Z2P2Primary (citable) accession number: F2Z2P2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 31, 2011 |
Last sequence update: | May 31, 2011 | |
Last modified: | December 2, 2020 | |
This is version 55 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |