UniProtKB - F1T0I5 (F1T0I5_HUMAN)
Protein
Submitted name:
Arylalkylamine N-acetyltransferase
Gene
AANAT
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- N-acetyltransferase activity Source: InterPro
Keywordsi
Molecular function | TransferaseImported |
Names & Taxonomyi
Protein namesi | Submitted name: Arylalkylamine N-acetyltransferaseImportedSubmitted name: Serotonin N-acetyltransferaseImported |
Gene namesi | Name:AANATImported ORF Names:hCG_30892Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
EuPathDBi | HostDB:ENSG00000129673.9 |
Subcellular locationi
Cytosol
- cytosol Source: HPA
Pathology & Biotechi
Chemistry databases
DrugBanki | DB09061, Cannabidiol DB14009, Medical Cannabis DB14011, Nabiximols |
Expressioni
Gene expression databases
Bgeei | ENSG00000129673, Expressed in frontal cortex and 102 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 35 – 194 | N-acetyltransferaseInterPro annotationAdd BLAST | 160 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 28 | DisorderedSequence analysisAdd BLAST | 28 |
Phylogenomic databases
HOGENOMi | CLU_061829_3_1_1 |
Family and domain databases
InterProi | View protein in InterPro IPR016181, Acyl_CoA_acyltransferase IPR000182, GNAT_dom |
Pfami | View protein in Pfam PF00583, Acetyltransf_1, 1 hit |
SUPFAMi | SSF55729, SSF55729, 1 hit |
PROSITEi | View protein in PROSITE PS51186, GNAT, 1 hit |
i Sequence
Sequence statusi: Complete.
F1T0I5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTQSTHPLK PEAPRLPPGI PESPSCQRRH TLPASEFRCL TPEDAVSAFE
60 70 80 90 100
IEREAFISVL GVCPLYLDEI RHFLTLCPEL SLGWFEEGCL VAFIIGSLWD
110 120 130 140 150
KERLMQESLT LHRSGGHIAH LHVLAVHRAF RQQGRGPILL WRYLHHLGSQ
160 170 180 190 200
PAVRRAALMC EDALVPFYER FSFHAVGPCA ITVGSLTFME LHCSLRGHPF
LRRNSGC
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB593119 mRNA Translation: BAJ84059.1 CH471099 Genomic DNA Translation: EAW89400.1 |
RefSeqi | NP_001079.1, NM_001088.2 |
Genome annotation databases
GeneIDi | 15 |
KEGGi | hsa:15 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB593119 mRNA Translation: BAJ84059.1 CH471099 Genomic DNA Translation: EAW89400.1 |
RefSeqi | NP_001079.1, NM_001088.2 |
3D structure databases
SMRi | F1T0I5 |
ModBasei | Search... |
Chemistry databases
BindingDBi | F1T0I5 |
DrugBanki | DB09061, Cannabidiol DB14009, Medical Cannabis DB14011, Nabiximols |
Protocols and materials databases
Antibodypediai | 32420, 275 antibodies |
DNASUi | 15 |
Genome annotation databases
GeneIDi | 15 |
KEGGi | hsa:15 |
Organism-specific databases
CTDi | 15 |
EuPathDBi | HostDB:ENSG00000129673.9 |
Phylogenomic databases
HOGENOMi | CLU_061829_3_1_1 |
Miscellaneous databases
BioGRID-ORCSi | 15, 2 hits in 839 CRISPR screens |
ChiTaRSi | AANAT, human |
GenomeRNAii | 15 |
Gene expression databases
Bgeei | ENSG00000129673, Expressed in frontal cortex and 102 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR016181, Acyl_CoA_acyltransferase IPR000182, GNAT_dom |
Pfami | View protein in Pfam PF00583, Acetyltransf_1, 1 hit |
SUPFAMi | SSF55729, SSF55729, 1 hit |
PROSITEi | View protein in PROSITE PS51186, GNAT, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F1T0I5_HUMAN | |
Accessioni | F1T0I5Primary (citable) accession number: F1T0I5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 31, 2011 |
Last sequence update: | May 31, 2011 | |
Last modified: | December 2, 2020 | |
This is version 83 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |