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Entry version 63 (17 Jun 2020)
Sequence version 1 (03 May 2011)
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Protein
Submitted name:

Glycerate kinase

Gene

GLYCTK

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SSC-70350 Fructose catabolism

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Glycerate kinaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GLYCTKImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008227 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:88504 GLYCTK

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
F1SIX9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSSSCG00000011432 Expressed in liver and 5 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F1SIX9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
F1SIX9 SS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000012184

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3935 Eukaryota
COG2379 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014365

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_032279_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F1SIX9

KEGG Orthology (KO)

More...
KOi
K11529

Identification of Orthologs from Complete Genome Data

More...
OMAi
ICGGEPV

Database of Orthologous Groups

More...
OrthoDBi
1371490at2759

TreeFam database of animal gene trees

More...
TreeFami
TF313770

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.1480.10, 1 hit
3.40.50.10180, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037035 GK-like_C_sf
IPR038614 GK_N_sf
IPR007835 MOFRL
IPR025286 MOFRL_assoc_dom
IPR039760 MOFRL_protein

The PANTHER Classification System

More...
PANTHERi
PTHR12227 PTHR12227, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13660 DUF4147, 1 hit
PF05161 MOFRL, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1SIX9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAIALQVLRH FARAPSRPLL WGCPLTRLAS GMALEEQARQ IFESTVGAML
60 70 80 90 100
PGPMLQRALS LDPDSGQLKV RDRSFQLRQN LYLVGFGKAV LGMAAAAEEL
110 120 130 140 150
LGQHLVQGVI SVPRGIRAAM EHAGKQEMLL KPHSRVQVFE GAEDNLPDRD
160 170 180 190 200
ALRAALAIRQ LAEGLTADDL LLVLISGGGS ALLPAPIPPV TLEEKQKLTK
210 220 230 240 250
LLAARGANIQ ELNTIRKALS QLKGGGLAQA AYPAQVVSLI LSDVVGDPVE
260 270 280 290 300
VIASGPTVAS VHSVQDCLHI LNRYGLRAAL PRSVKTVLAR ADSDPHGPHA
310 320 330 340 350
CGHVLNVIIG SNALALAEAQ KQAEALGYKA VVLSTAIQGD VKNVAQFYGL
360 370 380 390 400
LARVAGACLT MPAAGTSVEE DKQLYELAAQ LQLPDLQLKE ALEAVVGAQG
410 420 430 440 450
PVCLLAGGEP TVQLQGSGKG GRNQELALRV GVELGQWPLE PIDVLFLSGG
460 470 480 490 500
TDGQDGPTEA AGAWVRPELA RQAVAEGLDV AAFLAHNDSY TFFCRFQGGA
510 520
HLLHTGLTGT NVMDTHLLFL RPR
Length:523
Mass (Da):55,248
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8CAD09C7A2367005
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEMK02000086 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_003132296.1, XM_003132248.4
XP_005669684.1, XM_005669627.2
XP_005669685.1, XM_005669628.2
XP_005669686.1, XM_005669629.2
XP_013837215.1, XM_013981761.1
XP_013837217.1, XM_013981763.1
XP_013837218.1, XM_013981764.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000012512; ENSSSCP00000012184; ENSSSCG00000011432

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100522516

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ssc:100522516

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000086 Genomic DNA No translation available.
RefSeqiXP_003132296.1, XM_003132248.4
XP_005669684.1, XM_005669627.2
XP_005669685.1, XM_005669628.2
XP_005669686.1, XM_005669629.2
XP_013837215.1, XM_013981761.1
XP_013837217.1, XM_013981763.1
XP_013837218.1, XM_013981764.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000012184

Proteomic databases

PeptideAtlasiF1SIX9

Genome annotation databases

EnsembliENSSSCT00000012512; ENSSSCP00000012184; ENSSSCG00000011432
GeneIDi100522516
KEGGissc:100522516

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
132158
VGNCiVGNC:88504 GLYCTK

Phylogenomic databases

eggNOGiKOG3935 Eukaryota
COG2379 LUCA
GeneTreeiENSGT00390000014365
HOGENOMiCLU_032279_0_0_1
InParanoidiF1SIX9
KOiK11529
OMAiICGGEPV
OrthoDBi1371490at2759
TreeFamiTF313770

Enzyme and pathway databases

ReactomeiR-SSC-70350 Fructose catabolism

Gene expression databases

BgeeiENSSSCG00000011432 Expressed in liver and 5 other tissues
ExpressionAtlasiF1SIX9 baseline and differential
GenevisibleiF1SIX9 SS

Family and domain databases

Gene3Di3.40.1480.10, 1 hit
3.40.50.10180, 1 hit
InterProiView protein in InterPro
IPR037035 GK-like_C_sf
IPR038614 GK_N_sf
IPR007835 MOFRL
IPR025286 MOFRL_assoc_dom
IPR039760 MOFRL_protein
PANTHERiPTHR12227 PTHR12227, 1 hit
PfamiView protein in Pfam
PF13660 DUF4147, 1 hit
PF05161 MOFRL, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1SIX9_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1SIX9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: June 17, 2020
This is version 63 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
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