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Protein
Submitted name:

Glutaryl-CoA dehydrogenase, mitochondrial

Gene

GCDH

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

FADUniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

ReactomeiR-SSC-71064 Lysine catabolism

Names & Taxonomyi

Protein namesi
Submitted name:
Glutaryl-CoA dehydrogenase, mitochondrialImported
Gene namesi
Name:GCDHImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 2

PTM / Processingi

Proteomic databases

PaxDbiF1SD94
PeptideAtlasiF1SD94
PRIDEiF1SD94

Expressioni

Gene expression databases

ExpressionAtlasiF1SD94 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000014618

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 160Acyl-CoA_dh_NInterPro annotationAdd BLAST111
Domaini164 – 257Acyl-CoA_dh_MInterPro annotationAdd BLAST94
Domaini277 – 416Acyl-CoA_dh_1InterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the acyl-CoA dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0138 Eukaryota
COG1960 LUCA
GeneTreeiENSGT00760000119007
InParanoidiF1SD94
TreeFamiTF105051

Family and domain databases

Gene3Di1.10.540.10, 1 hit
InterProiView protein in InterPro
IPR006089 Acyl-CoA_DH_CS
IPR006091 Acyl-CoA_Oxase/DH_cen-dom
IPR036250 AcylCo_DH-like_C
IPR009075 AcylCo_DH/oxidase_C
IPR013786 AcylCoA_DH/ox_N
IPR037069 AcylCoA_DH/ox_N_sf
IPR009100 AcylCoA_DH/oxidase_NM_dom
PfamiView protein in Pfam
PF00441 Acyl-CoA_dh_1, 1 hit
PF02770 Acyl-CoA_dh_M, 1 hit
PF02771 Acyl-CoA_dh_N, 1 hit
SUPFAMiSSF47203 SSF47203, 1 hit
SSF56645 SSF56645, 1 hit
PROSITEiView protein in PROSITE
PS00073 ACYL_COA_DH_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.iShow all

F1SD94-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFLRSVYARL LSRGPCLRVL RSWGSAAAQT ASRPEFDWRD PLVLEEQLTA
60 70 80 90 100
DEILIRDTFR TYCQEHLMPR IVLANRNEVF HREIISEMGE LGVLGPTIKG
110 120 130 140 150
YGCAGVSSVA YGLLARELER VDSGYRSAMS VQSSLVMHPI YAYGSEEQQQ
160 170 180 190 200
KYLPRLAKGE LLGCFGLTEP NHGSDPGSME TRARHNPSNR SYTLNGAKTW
210 220 230 240 250
ITNSPVADLF VVWARCEDNC IRGFLLEKGM RGLSAPKIEG KFSLRASATG
260 270 280 290 300
MIIMDDVEVP EENVLPKASS LAGPFGCLNN ARYGISWGVL GAAEFCLHTA
310 320 330 340 350
RQYTLDRIQF GVPLAKNQLI QRKLADMLTE ITLGLHACLQ LGRLKDQDKV
360 370 380 390 400
TPEMVSLLKR NNCGKALDIA RQARDMLGGN GISDEYHVIR HAMNLEAVNT
410 420
YEGTHDIHAL ILGRAITGIQ AFTTDK
Length:426
Mass (Da):47,229
Last modified:November 22, 2017 - v3
Checksum:iC23D5534D136755E
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P81140GCDH_PIG
Glutaryl-CoA dehydrogenase, mitocho...
GCDH
408Annotation score:
A0A287BLJ2A0A287BLJ2_PIG
Glutaryl-CoA dehydrogenase, mitocho...
GCDH
438Annotation score:
F1SEX3F1SEX3_PIG
Glutaryl-CoA dehydrogenase, mitocho...
GCDH
417Annotation score:
A0A286ZXI1A0A286ZXI1_PIG
Glutaryl-CoA dehydrogenase, mitocho...
GCDH
396Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000012 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSSSCT00000015023; ENSSSCP00000014618; ENSSSCG00000013729

Similar proteinsi

Entry informationi

Entry nameiF1SD94_PIG
AccessioniPrimary (citable) accession number: F1SD94
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: November 22, 2017
Last modified: May 23, 2018
This is version 42 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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