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Entry version 66 (12 Aug 2020)
Sequence version 2 (11 Jul 2012)
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Protein

Phosphoacetylglucosamine mutase

Gene

PGM3

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+1 PublicationNote: Binds 1 Mg2+ ion per subunit.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Inhibited by Mn2+, Cd2+, Zn2+, Cu2+ and Be2+.1 Publication

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.29 mM for D-glucosamine 1-phosphate1 Publication
  2. KM=0.39 mM for D-glucose 1-phosphate1 Publication
  3. KM=0.018 mM for fructose 1,6-diphosphate1 Publication
  4. KM=0.016 mM for galactose 1,6-diphosphate1 Publication
  5. KM=0.005 mM for mannose 1,6-diphosphate1 Publication
  6. KM=0.002 mM for glucose 1,6-diphosphate1 Publication
  1. Vmax=39.4 µmol/min/mg enzyme for D-glucosamine 1-phosphate1 Publication
  2. Vmax=28.9 µmol/min/mg enzyme for D-glucose 1-phosphate1 Publication
  3. Vmax=10.1 µmol/min/mg enzyme for fructose 1,6-diphosphate1 Publication
  4. Vmax=14.3 µmol/min/mg enzyme for galactose 1,6-diphosphate1 Publication
  5. Vmax=26.7 µmol/min/mg enzyme for mannose 1,6-diphosphate1 Publication
  6. Vmax=34.4 µmol/min/mg enzyme for glucose 1,6-diphosphate1 Publication

pH dependencei

Optimum pH is 7-7.5.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: UDP-N-acetyl-alpha-D-glucosamine biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I).1 Publication
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1), Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1), Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1), Glucosamine 6-phosphate N-acetyltransferase (GNPNAT1), Glucosamine 6-phosphate N-acetyltransferase
  2. Phosphoacetylglucosamine mutase, Phosphoacetylglucosamine mutase (PGM3), Phosphoacetylglucosamine mutase (PGM3), Phosphoacetylglucosamine mutase, Phosphoacetylglucosamine mutase (PGM3), Phosphoacetylglucosamine mutase (PGM3)
This subpathway is part of the pathway UDP-N-acetyl-alpha-D-glucosamine biosynthesis, which is itself part of Nucleotide-sugar biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I), the pathway UDP-N-acetyl-alpha-D-glucosamine biosynthesis and in Nucleotide-sugar biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei64Phosphoserine intermediateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi64Magnesium; via phosphate groupBy similarity1
Metal bindingi276MagnesiumBy similarity1
Metal bindingi278MagnesiumBy similarity1
Metal bindingi280MagnesiumBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei505SubstrateBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIsomerase
Biological processCarbohydrate metabolism
LigandMagnesium, Metal-binding

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00113;UER00530

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phosphoacetylglucosamine mutase1 Publication (EC:5.4.2.32 Publications)
Short name:
PAGMCurated
Short name:
PGlcNAc mutase1 Publication
Alternative name(s):
Acetylglucosamine phosphomutaseCurated
N-acetylglucosamine-phosphate mutaseBy similarity
Phosphoglucomutase-3By similarity
Short name:
PGM 3By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PGM3By similarity
Synonyms:AGM1By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000314985 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1
  • UP000008227 Componenti: Unplaced

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004312961 – 542Phosphoacetylglucosamine mutaseAdd BLAST542

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
Modified residuei62PhosphothreonineBy similarity1
Modified residuei64PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F1RQM2

PeptideAtlas

More...
PeptideAtlasi
F1RQM2

PRoteomics IDEntifications database

More...
PRIDEi
F1RQM2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSSSCG00000004456, Expressed in pituitary gland and 39 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
F1RQM2, SS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000004806

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F1RQM2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni370 – 372Substrate bindingBy similarity3
Regioni496 – 500Substrate bindingBy similarity5

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the phosphohexose mutase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2537, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_022890_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F1RQM2

KEGG Orthology (KO)

More...
KOi
K01836

Database of Orthologous Groups

More...
OrthoDBi
345441at2759

TreeFam database of animal gene trees

More...
TreeFami
TF105670

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03086, PGM3, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005844, A-D-PHexomutase_a/b/a-I
IPR016055, A-D-PHexomutase_a/b/a-I/II/III
IPR005843, A-D-PHexomutase_C
IPR036900, A-D-PHexomutase_C_sf
IPR016066, A-D-PHexomutase_CS
IPR016657, PAGM

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02878, PGM_PMM_I, 2 hits
PF00408, PGM_PMM_IV, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF016408, PAGM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53738, SSF53738, 4 hits
SSF55957, SSF55957, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00710, PGM_PMM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F1RQM2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDLDAITKHS ASHAKPDGLI LQYGTAGFRT KADRLDHVMF RMGLLAVLRS
60 70 80 90 100
KQTKSTIGVM VTASHNPEDD NGVKLVDPLG EMLAPSWEEH ATHLANAEEQ
110 120 130 140 150
DLARALVAIS EEAAVNLHQD AFVVIGRDTR PSSEKLSESV IDGVTVLGGQ
160 170 180 190 200
FHDYGLLTTP QLHYMVCCRN TGGQYGEATI DGYYHKLSTA FVELSKQASC
210 220 230 240 250
SGDDHRTLKV DCANGIGALK LKEMKHYLPQ GLSVQLFNDG TKGKLNHFCG
260 270 280 290 300
ADFVKSHQKP PEGIEMKANE RCCSFDGDAD RIIYYYCDVD GHFHLIDGDK
310 320 330 340 350
IATLISSFLK ELLLEIGESL TVGVVQTAYA NGSSTRYLEE VMKVPVYCTK
360 370 380 390 400
TGVKHLHHKA QEFDLGVYFE ANGHGTVLFS KAAEAKIRQL AKELEDKKGK
410 420 430 440 450
AAKMLENVID LFNQATGDAI SDMLVIEAIL ALKGLTIQQW DALYTDLPNR
460 470 480 490 500
QLKVKVADRQ VISTTDAERQ VVKPPGLQEA INDLVKKYKL SRAFVRPSGT
510 520 530 540
EDVVRVYAEA DSQENADSLA YEVSLAVFQQ AGGVGERPQP GF
Length:542
Mass (Da):59,474
Last modified:July 11, 2012 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA5C7A8492751E150
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEMK01179872 Genomic DNA No translation available.
CU463150 Genomic DNA No translation available.
GACC01000082 mRNA Translation: JAA53725.1

NCBI Reference Sequences

More...
RefSeqi
XP_001924454.2, XM_001924419.4
XP_005659464.1, XM_005659407.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00030022007; ENSSSCP00030009944; ENSSSCG00030015873
ENSSSCT00035094807; ENSSSCP00035039836; ENSSSCG00035070159
ENSSSCT00045016316; ENSSSCP00045011275; ENSSSCG00045009611
ENSSSCT00050021173; ENSSSCP00050008843; ENSSSCG00050015639
ENSSSCT00055030841; ENSSSCP00055024560; ENSSSCG00055015625
ENSSSCT00065069324; ENSSSCP00065030198; ENSSSCG00065050601
ENSSSCT00070043212; ENSSSCP00070036361; ENSSSCG00070021741

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100156015

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ssc:100156015

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK01179872 Genomic DNA No translation available.
CU463150 Genomic DNA No translation available.
GACC01000082 mRNA Translation: JAA53725.1
RefSeqiXP_001924454.2, XM_001924419.4
XP_005659464.1, XM_005659407.2

3D structure databases

SMRiF1RQM2
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000004806

Proteomic databases

PaxDbiF1RQM2
PeptideAtlasiF1RQM2
PRIDEiF1RQM2

Genome annotation databases

EnsembliENSSSCT00030022007; ENSSSCP00030009944; ENSSSCG00030015873
ENSSSCT00035094807; ENSSSCP00035039836; ENSSSCG00035070159
ENSSSCT00045016316; ENSSSCP00045011275; ENSSSCG00045009611
ENSSSCT00050021173; ENSSSCP00050008843; ENSSSCG00050015639
ENSSSCT00055030841; ENSSSCP00055024560; ENSSSCG00055015625
ENSSSCT00065069324; ENSSSCP00065030198; ENSSSCG00065050601
ENSSSCT00070043212; ENSSSCP00070036361; ENSSSCG00070021741
GeneIDi100156015
KEGGissc:100156015

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
5238

Phylogenomic databases

eggNOGiKOG2537, Eukaryota
HOGENOMiCLU_022890_1_0_1
InParanoidiF1RQM2
KOiK01836
OrthoDBi345441at2759
TreeFamiTF105670

Enzyme and pathway databases

UniPathwayiUPA00113;UER00530

Gene expression databases

BgeeiENSSSCG00000004456, Expressed in pituitary gland and 39 other tissues
GenevisibleiF1RQM2, SS

Family and domain databases

CDDicd03086, PGM3, 1 hit
InterProiView protein in InterPro
IPR005844, A-D-PHexomutase_a/b/a-I
IPR016055, A-D-PHexomutase_a/b/a-I/II/III
IPR005843, A-D-PHexomutase_C
IPR036900, A-D-PHexomutase_C_sf
IPR016066, A-D-PHexomutase_CS
IPR016657, PAGM
PfamiView protein in Pfam
PF02878, PGM_PMM_I, 2 hits
PF00408, PGM_PMM_IV, 1 hit
PIRSFiPIRSF016408, PAGM, 1 hit
SUPFAMiSSF53738, SSF53738, 4 hits
SSF55957, SSF55957, 1 hit
PROSITEiView protein in PROSITE
PS00710, PGM_PMM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAGM1_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1RQM2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 26, 2014
Last sequence update: July 11, 2012
Last modified: August 12, 2020
This is version 66 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
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