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Entry version 74 (29 Sep 2021)
Sequence version 3 (22 Nov 2017)
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Protein
Submitted name:

Fibrocystin isoform X1

Gene

PKHD1

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Fibrocystin isoform X1Imported
Submitted name:
PKHD1 ciliary IPT domain containing fibrocystin/polyductinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PKHD1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008227 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:91476, PKHD1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3850 – 3873HelicalSequence analysisAdd BLAST24

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_502664620321 – 4075Sequence analysisAdd BLAST4055

Keywords - PTMi

GlycoproteinARBA annotation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F1RKV2

PRoteomics IDEntifications database

More...
PRIDEi
F1RKV2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSSSCG00000001746, Expressed in metanephros cortex and 11 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F1RKV2, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000001903

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini323 – 483PA14InterPro annotationAdd BLAST161
Domaini1925 – 2046G8InterPro annotationAdd BLAST122
Domaini2740 – 2866G8InterPro annotationAdd BLAST127

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni3935 – 3975DisorderedSequence analysisAdd BLAST41

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QR85, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160697

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000057_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F1RKV2

TreeFam database of animal gene trees

More...
TreeFami
TF329582

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.160.20.10, 2 hits
2.60.40.10, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039448, Beta_helix
IPR019316, G8_domain
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR002909, IPT_dom
IPR037524, PA14/GLEYA
IPR006626, PbH1
IPR012334, Pectin_lyas_fold
IPR011050, Pectin_lyase_fold/virulence
IPR028839, PKHD1

The PANTHER Classification System

More...
PANTHERi
PTHR46769:SF1, PTHR46769:SF1, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13229, Beta_helix, 1 hit
PF10162, G8, 2 hits
PF01833, TIG, 7 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01225, G8, 2 hits
SM00429, IPT, 5 hits
SM00710, PbH1, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51126, SSF51126, 2 hits
SSF81296, SSF81296, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51484, G8, 2 hits
PS51820, PA14, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

F1RKV2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTGWLISLTN IEILLLAVSC LRVRIEPEEG SLAGGTWITV FFDGLELGLL
60 70 80 90 100
YPANGTQLEI HLVNMAVPSL PRIPCDISPL FLDLPAVMCK TRSLLSEAHE
110 120 130 140 150
GLYYLEVQSG GQVAGSPSPG PGDSCTFKFS RAQTPIVYQV NPSSGVPGNL
160 170 180 190 200
IDVYGWIVTG SLETFDFDTE YIDSPLLLEA HGDEWVTPCS LVNRQTGCRY
210 220 230 240 250
PIQEDHGLGT LQCRVEGSYI GSQNVSFSVV NKGKSMVHKN AWLVSAKQDL
260 270 280 290 300
FLYQTYSEIL SVFPETGSLG GRTDITIIGD FFDNPAQVTI AGIPCDIRHV
310 320 330 340 350
SPRKIECTTR APGRGTRLSA PQAGNRGLLF EVGDAPEGLD LTEATPGYRW
360 370 380 390 400
QIVPNASAPF GFWSKEGQPF RARLSGFFVA PETNNYTFWI QADNQASLYF
410 420 430 440 450
SRSEDPKTKV KVASIMVGTA SWFDSWEQNG GEEIWAQKTP QLELLGGARY
460 470 480 490 500
YLEAEHQGRA PSSGVRIGVQ IHNTWLNPEV VNTYLREKHQ IRAHAQRLPE
510 520 530 540 550
IQMLTVSGTG NFFLTWDNVS SQPIPANATA YQIQTAIEEL LAVKCKLEPL
560 570 580 590 600
SANILLRLGF EQGPEGSSSD GNITSGTEPF CGRFSLHQPH HLVLTPPAAQ
610 620 630 640 650
RGYRLDQYTH LCIAYKAHVY TILRVTLSFT IGFQNTVKKN VTCDWSLAGT
660 670 680 690 700
SPSSWQFTCT DLWKVCVQRS LPLQPPPVNS SVLVHQIVLL PLSPEMGVFS
710 720 730 740 750
VDEIFIADTN LTVSQADSGT ARPGGNLVEL LSVVGSPPVY NVTSWLVGCG
760 770 780 790 800
LELPLISASS VLPEGAEEGS GLVQVTTQRL QRTSPPLGGH FRIHLSNTEI
810 820 830 840 850
PGVPVHISAS HLQKLLQNNA DDFTSRYLNV SDFTVTEALK SCYEHVWTLS
860 870 880 890 900
WSTQVGDLPN FIRVSDENLT GVNPAVTARV VYDGGVFLGP IFGDMLVTPN
910 920 930 940 950
QNTQVVVRVN DIPAHCSGSC SFQYLEGSTP QVHAVWYAPD DNGLLVHITG
960 970 980 990 1000
MRFSDDLEAL QVRVNKTSCK VIFSNQTNVM CQLGLLPVGK HQLTMLVRPS
1010 1020 1030 1040 1050
GLAIHARGGG LFLNVEPRLD AVEPSRAADI GGFWATIQGS SLEDVSLVLF
1060 1070 1080 1090 1100
GSQSCTINVT TSNSQRIQCK VPPLGNDGPI VNVTVIRGDH SVVLPMAFTY
1110 1120 1130 1140 1150
VSSLNPVIVS LSRNRSNIAG GETLSIGMAL PVNYTDLDAE VHIGDTQAQV
1160 1170 1180 1190 1200
LTWTAWGLEV VLPPLPTGLH GISVSINRVR IGAQGVDLHI QYLTEVFSIQ
1210 1220 1230 1240 1250
PCCGSLLGGT ILSISGRGFS PNSALVQVLV GNRSCEVVNS TERSIWCETP
1260 1270 1280 1290 1300
PAPLPPGVPA RVEVWAGGEP SPHRPLPSLV AGGFTFTYEE AATPVVTATR
1310 1320 1330 1340 1350
GEMTHHSLRL YVEGHNLSDS VVLLGGLSCD LEPQLLVGNT SLSACTFPLG
1360 1370 1380 1390 1400
SLEAGTYPLQ VRQRQMGFAD LPAGSQKFVV TPQITALSPT HGSTCGGTVL
1410 1420 1430 1440 1450
TVIGSAFSSS RRSVQVDLSG PYSCVILSLG DQTVLCRITL SDDPLPGASF
1460 1470 1480 1490 1500
TLNVTVLVNG LPSECLGNCT LSLCEETTPV LDAWTVNISG SLTTVLIRGQ
1510 1520 1530 1540 1550
RLGITAKAPV VLVDDLLLCT VTFFNTSHIA CWISDLAPGP HSLSIFHARY
1560 1570 1580 1590 1600
GYACSGNISR HFDILPRVFH YFPKNFSLHG GGLLTMEGTA LRARNTTLVS
1610 1620 1630 1640 1650
VGRQACLTLN LSSDLIQCSV PAGSGSVALD LEVDGLSYQV GVIHYSHAFT
1660 1670 1680 1690 1700
PKLLSVSHTD DTLTLLVAGI SDSLNVDIFI GVSPCVGVSG NHTVLQCLAP
1710 1720 1730 1740 1750
PLPAGRYQVR GYDHSRGWAS SDLVLVSRVT ITAVTENFGC LGGRLVHVFG
1760 1770 1780 1790 1800
AGFSPGNISA ALCGASCQVL ANTTVSAFSC LVPPLDVSLA FLCGLRLEEE
1810 1820 1830 1840 1850
DCVASSSSYV QCDLTVTVGT ERLPESWPYF YMCGESSRCL FVQDHWTESV
1860 1870 1880 1890 1900
FPSLSGLLIS PKVERDEVLI YNSSCTITME TEAKMECETP NQPITAKITE
1910 1920 1930 1940 1950
IRKSWGQNTQ GNFPFQFCGR WSRAHSWFSG RRPQEGDNVT VEKGQLLLLD
1960 1970 1980 1990 2000
TNTSILNFLH VKGGKLIFLD PGPIELRAHA ILVSDGGELR IGSKDKPFRG
2010 2020 2030 2040 2050
KASIKLYGSA YTTPFFPYGV KFLAVRNGTL SLHGSLPEVV VTHLRAAASA
2060 2070 2080 2090 2100
GDTVLALEDA VDWHPGDEVV VISGMGADDA EPMEEIVTVE TMRGADLHLR
2110 2120 2130 2140 2150
SPLRFSHNAT ENWMAGEHHV LKVMVAVLSR SITLQGNFTE ERLKFLASCQ
2160 2170 2180 2190 2200
GASSSGNLQN CLYSKSEKML GSRDLGARVI IQSFPEEPSQ VQLEGVQLRD
2210 2220 2230 2240 2250
LGQAFREHVS SLTLVGTLSG SYVQGCTVWL SFSRGLSMSR TSGLKVDSNV
2260 2270 2280 2290 2300
FYDILGHALL VGTSPEIRYI PSEVIPTGEN DWPEQGNIIR NNVIIRVAGA
2310 2320 2330 2340 2350
EGLSSPEMLA PSGIYIRDPT NVVEGNQVCA SGYGYFFHLV TNQTSQAPLL
2360 2370 2380 2390 2400
SFTRNSAHSC TRSGLIVYPK FQPPWDNGTG PTLFQHFTVW GSAGGAQIFR
2410 2420 2430 2440 2450
SSNLRLENFQ VYACRDFGID ILESDANTSV TDSLLLGHFA HKGSLCMSAG
2460 2470 2480 2490 2500
IKTPKRWELI ISNTTFMNFD LADCVAIRTC SGCSRGQGGF TVKTNQLKFT
2510 2520 2530 2540 2550
NSSNLVAFPF PHAAILEDVD GSLSGKNRSH ILASMETLSA SCLVKASFSQ
2560 2570 2580 2590 2600
LVHGSVCEEN VLFHRMSIGL ASAPKIPYDL TITDSKNKTT TVSYVHNTLS
2610 2620 2630 2640 2650
NLYGWMALLL DQETYSLQFD SPWSNCSLQY SATFDNFAPG NYLLIVHTDM
2660 2670 2680 2690 2700
PWPHPDILVG CGSQVGRALP SLPSPGQDQG CDWFFHSHLR QLTYLVSGEG
2710 2720 2730 2740 2750
QIQVLLQVRE GVAPTISDST PARESSIKWS LPDAWEGVEK GWGGHGGTIP
2760 2770 2780 2790 2800
GSGDDVLILP NRTVLVDTDL PLLRGLYVRG TLEFPVDRSN VLNVTCMVIA
2810 2820 2830 2840 2850
GGELRVGTLE NPLGKEKKLL IFLRASEGVF CDRFNGIRID PGTIGVFGKV
2860 2870 2880 2890 2900
QLHSAYSKKS WTHLGADIAS GNERIIVEDA VDWRPQDKIV LSSSSYEPHE
2910 2920 2930 2940 2950
AEVLTVKEVR GHHVRIHERL RHRHIGSVHI MEDGRKVRLA AEVGLLTRNI
2960 2970 2980 2990 3000
QIQGDTACGG SLLVGSFRKS NGEEFSGVLQ LLNVEIQNFG SPLYSSIELT
3010 3020 3030 3040 3050
NVSAGSWIIS STLHQSCGGG IHAAASHGII LNDNVVFGTA GHGIHLEGQN
3060 3070 3080 3090 3100
YSLSKNLVVL MTQSAWSPVW VAGIKVNQAK DIHLHGNAVG GSERLGFHIR
3110 3120 3130 3140 3150
GHRCSSSEVL WSDNVAHSSL HGVHLYKESG PNNCTSISGF LAFKNFDYGA
3160 3170 3180 3190 3200
MLQGENSMQI ENITLVDNAV GLLAVVYVSS APQCYIRNRE IVLRNSVIVA
3210 3220 3230 3240 3250
TSSSFDCIQD RVKPRSANWT SADRAPSSPR GGRVGILWPV FTSEPNRWPQ
3260 3270 3280 3290 3300
EPWHKVRNGH LISGIMKLQG VTFSSFVKSC YSNDLDVCIV SSSENTGIVP
3310 3320 3330 3340 3350
PITAERTRML KIKDKNKFYF PPLQTRKDLR LVCSESDCES PRKYLFKDLD
3360 3370 3380 3390 3400
GRALGLPPPV SVFLKTEGEW TGSFFNTGTF REEQKCTYRA PIQGYICKQT
3410 3420 3430 3440 3450
DQVILILDSA DATWAMQKLY PVVSVTSGFV DTFSSINANT PCSTSGSVSA
3460 3470 3480 3490 3500
FYSILPTREI TKVCFVDQTP QILRFFLLGN KSTSKLLLAV FYHELQSPHV
3510 3520 3530 3540 3550
FLGERLIPPT LVQSASSLLN EPIGSNYFSI MDNLLYVVLQ GEEPVEIRSG
3560 3570 3580 3590 3600
VAIHLALTVM FSVLEKGWEV MILERLTDFL KVCQDQIRLI HEIPGDESTL
3610 3620 3630 3640 3650
KTIADSKTKR KRNCPIVTCV NHDRAGQRRP LMIEMSSYRV LSPTTMDTVS
3660 3670 3680 3690 3700
KVMVIEIGDP PTMRNTGPIP SLSSNKLQSL AHQVITAHQI GVLENALNIT
3710 3720 3730 3740 3750
VGALLVTQSK GIISSGNTSS FETGNLIYIR PSALKVLVQP SDGEVGRELT
3760 3770 3780 3790 3800
VQPQLVFLDK QNRTVESLGP PSEPWAISVS LEGTSDSVLR GCTWAETQDG
3810 3820 3830 3840 3850
YVSFSNLAVL ISGSNWHFIF TVTSPPGANF TARSRSFAVL PATPSEKSTI
3860 3870 3880 3890 3900
ILAAFLCSGV SWMALCCLVC CWFKKSKSRK IKSEEISESQ INDPKNCIHV
3910 3920 3930 3940 3950
LSKCQGTHVE TKKEGPVMAE DLRLKLMRGK LNQVPHHSLN GVSRRKLSRP
3960 3970 3980 3990 4000
AVREEGGSRG EAAVPSPSTS SVALHRNTSA PDLPVQQLCL QETESWKGAQ
4010 4020 4030 4040 4050
EQVLRYHLAG QDQMLLLCGD LRRERQRLQD QHCLGEENVN LGLSQEKAAS
4060 4070
CRATEVFCLH SVRSEAVQAA VIKKQ
Length:4,075
Mass (Da):443,218
Last modified:November 22, 2017 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i26B81465CCDB2361
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A287A5X4A0A287A5X4_PIG
PKHD1 ciliary IPT domain containing...
PKHD1
3,986Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A286ZWV0A0A286ZWV0_PIG
PKHD1 ciliary IPT domain containing...
PKHD1
4,037Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A287AWQ4A0A287AWQ4_PIG
PKHD1 ciliary IPT domain containing...
PKHD1
3,977Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEMK02000055 Genomic DNA No translation available.
DQIR01027121 Transcribed RNA Translation: HCZ82596.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000001952; ENSSSCP00000001903; ENSSSCG00000001746

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000055 Genomic DNA No translation available.
DQIR01027121 Transcribed RNA Translation: HCZ82596.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000001903

Proteomic databases

PaxDbiF1RKV2
PRIDEiF1RKV2

Genome annotation databases

EnsembliENSSSCT00000001952; ENSSSCP00000001903; ENSSSCG00000001746

Organism-specific databases

VGNCiVGNC:91476, PKHD1

Phylogenomic databases

eggNOGiENOG502QR85, Eukaryota
GeneTreeiENSGT00940000160697
HOGENOMiCLU_000057_1_0_1
InParanoidiF1RKV2
TreeFamiTF329582

Gene expression databases

BgeeiENSSSCG00000001746, Expressed in metanephros cortex and 11 other tissues
ExpressionAtlasiF1RKV2, baseline and differential

Family and domain databases

Gene3Di2.160.20.10, 2 hits
2.60.40.10, 5 hits
InterProiView protein in InterPro
IPR039448, Beta_helix
IPR019316, G8_domain
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR002909, IPT_dom
IPR037524, PA14/GLEYA
IPR006626, PbH1
IPR012334, Pectin_lyas_fold
IPR011050, Pectin_lyase_fold/virulence
IPR028839, PKHD1
PANTHERiPTHR46769:SF1, PTHR46769:SF1, 1 hit
PfamiView protein in Pfam
PF13229, Beta_helix, 1 hit
PF10162, G8, 2 hits
PF01833, TIG, 7 hits
SMARTiView protein in SMART
SM01225, G8, 2 hits
SM00429, IPT, 5 hits
SM00710, PbH1, 7 hits
SUPFAMiSSF51126, SSF51126, 2 hits
SSF81296, SSF81296, 6 hits
PROSITEiView protein in PROSITE
PS51484, G8, 2 hits
PS51820, PA14, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1RKV2_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1RKV2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: November 22, 2017
Last modified: September 29, 2021
This is version 74 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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