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Entry version 61 (05 Jun 2019)
Sequence version 1 (03 May 2011)
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Protein

Sodium channel protein

Gene

scn8ab

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient.UniRule annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIon channel, Sodium channelUniRule annotation, Voltage-gated channelUniRule annotation
Biological processIon transport, Sodium transport, Transport
LigandSodium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium channel proteinUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:scn8abImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-060906-2 scn8ab

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei130 – 153HelicalUniRule annotationAdd BLAST24
Transmembranei198 – 217HelicalUniRule annotationAdd BLAST20
Transmembranei229 – 250HelicalUniRule annotationAdd BLAST22
Transmembranei256 – 276HelicalUniRule annotationAdd BLAST21
Transmembranei350 – 369HelicalUniRule annotationAdd BLAST20
Transmembranei389 – 416HelicalUniRule annotationAdd BLAST28
Transmembranei727 – 745HelicalUniRule annotationAdd BLAST19
Transmembranei757 – 775HelicalUniRule annotationAdd BLAST19
Transmembranei837 – 865HelicalUniRule annotationAdd BLAST29
Transmembranei927 – 950HelicalUniRule annotationAdd BLAST24
Transmembranei1174 – 1192HelicalUniRule annotationAdd BLAST19
Transmembranei1213 – 1232HelicalUniRule annotationAdd BLAST20
Transmembranei1244 – 1264HelicalUniRule annotationAdd BLAST21
Transmembranei1290 – 1316HelicalUniRule annotationAdd BLAST27
Transmembranei1413 – 1439HelicalUniRule annotationAdd BLAST27
Transmembranei1498 – 1516HelicalUniRule annotationAdd BLAST19
Transmembranei1528 – 1550HelicalUniRule annotationAdd BLAST23
Transmembranei1562 – 1581HelicalUniRule annotationAdd BLAST20
Transmembranei1625 – 1650HelicalUniRule annotationAdd BLAST26
Transmembranei1718 – 1741HelicalUniRule annotationAdd BLAST24

Keywords - Cellular componenti

Membrane

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000018032 Expressed in 11 organ(s), highest expression level in brain

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000126281

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini133 – 422Ion_transInterPro annotationAdd BLAST290
Domaini495 – 673Na_trans_cytoplInterPro annotationAdd BLAST179
Domaini727 – 954Ion_transInterPro annotationAdd BLAST228
Domaini964 – 1167Na_trans_assocInterPro annotationAdd BLAST204
Domaini1172 – 1447Ion_transInterPro annotationAdd BLAST276
Domaini1497 – 1751Ion_transInterPro annotationAdd BLAST255

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni25 – 66DisorderedSequence analysisAdd BLAST42
Regioni445 – 528DisorderedSequence analysisAdd BLAST84
Regioni1085 – 1113DisorderedSequence analysisAdd BLAST29
Regioni1896 – 1958DisorderedSequence analysisAdd BLAST63

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi25 – 59PolyampholyteSequence analysisAdd BLAST35
Compositional biasi497 – 528PolyampholyteSequence analysisAdd BLAST32
Compositional biasi1901 – 1924PolarSequence analysisAdd BLAST24
Compositional biasi1926 – 1958PolyampholyteSequence analysisAdd BLAST33

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the sodium channel (TC 1.A.1.10) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2301 Eukaryota
ENOG410XNP6 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156263

Identification of Orthologs from Complete Genome Data

More...
OMAi
SIMMLIC

TreeFam database of animal gene trees

More...
TreeFami
TF323985

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005821 Ion_trans_dom
IPR008054 Na_channel_a8su
IPR001696 Na_channel_asu
IPR010526 Na_trans_assoc
IPR024583 Na_trans_cytopl
IPR027359 Volt_channel_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00520 Ion_trans, 4 hits
PF06512 Na_trans_assoc, 1 hit
PF11933 Na_trans_cytopl, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00170 NACHANNEL
PR01667 NACHANNEL8

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

F1RE76-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAPLLAPPG PDSFKRFTPE SLANIEKRIA EEKKKKPVKP RSDSSHRDDD
60 70 80 90 100
DDNKPKPNSD LEAGKGVPFI YGDVPSNMLA VPLEDLDPFY LNKKTFIVLN
110 120 130 140 150
KGKTIFRFSA TPSLYIISPF NLFRQIAIKI LIHSFFSMII MCTILTNCVF
160 170 180 190 200
MTFSNPPEWS KQVEYTFTGI YTFESLTKIV ARGFCIDDFT FLRDPWNWLD
210 220 230 240 250
FMVISMAYVT EFVDLGNVSA LRTFRVLRAL KTISVIPGLK TIVGALIQSV
260 270 280 290 300
KKLSDVMILT VFCLSVFALI GLQLFMGNLR QKCVIWPVNS TETYLANGSK
310 320 330 340 350
GFDFNEYIMN DTNFYFLPGM LDALLCGNSS DSGRCPEGYT CMKAGRNPNY
360 370 380 390 400
GYTSFDSFGW AFLALFRLMT QDFWENLYQL TLRAAGKTYM IFFVLVIFVG
410 420 430 440 450
SFYLVNLILA VVAMAYEEQN QATIEEAEQK EAEFKAMLEQ LKKQQEEAQA
460 470 480 490 500
NAMATSAGTV SEDAVEDDGG GHLSRSSSEV SKLSSKSAKE RRNRKKKWRK
510 520 530 540 550
EQEEKGDSEK VVKSESDDGS KRSRFRFRDN RLGRKASIMN QSLLSIPGSP
560 570 580 590 600
FMSRRSSIFS FKGSENEFAD DEHSTVEESE DRRGSLFVPY RRSSYSGYSQ
610 620 630 640 650
GSSRINPLAP HPGCKRNSTV DCNGVVSLIG PGPGRLLPET TEVEGKRKHS
660 670 680 690 700
GSLMVSVDQL NTSFSRKERA NSAMTVVTNT LVEELEESQR KCPPCWYKFA
710 720 730 740 750
NTFLIWECCP IWIKIKEIVN LIVMDPFVDL AITICIVLNT VFMAMEHYPM
760 770 780 790 800
TPRFEEVLSV GNLVFTGIFT AEMFAKLIAM DPYYYFQEGW NIFDGFIVSL
810 820 830 840 850
SLVELGLADV EGLSVLRSFR LLRVFKLAKS WPTLNMLIKI IGNSVGALGN
860 870 880 890 900
LTLVLAIIVF IFAVVGMQLF GKSYKDCVCK IAESCELPRW HMNDFFHSFL
910 920 930 940 950
IVFRVLCGEW IETMWDCMEV AGQSMCLIVF MMVMVIGNLV VLNLFLALLL
960 970 980 990 1000
SSFSADNLAA TDDDGEMNNL QISVIRIKKG IAWFKIHVRL LVAHVLKKKP
1010 1020 1030 1040 1050
LEDEDKPLDD MYDKKLNLMG NHTGVEIKCG DLNYPKNGNG TTSGIGSSVG
1060 1070 1080 1090 1100
KYMIDEEPMS FIHNPNLTVR VPIAVGESDF ENLNTEDFSS ESDVENSKDL
1110 1120 1130 1140 1150
DDTSSSEGST IDIKPDEEEM AVVEVVEEYL DPEACWTDAC VARYKCCDVP
1160 1170 1180 1190 1200
ITEGWGKYWW FLRKTCYLIV EHNWFETLII FMILLSSGAL AFEDVYIEQR
1210 1220 1230 1240 1250
KTIQIILEYA DRVFTYIFIL EMLLKWVAYG FVKYFTNAWC WLDFFIVDVS
1260 1270 1280 1290 1300
IVSLIANALG YSDLGPIKSL RTLRALRPLR ALSRFEGMRV VVNALVGAIP
1310 1320 1330 1340 1350
SIMNVLLVCL IFWLIFSIMG VNLFAGKYYY CFNQTAEEYF QVDVVNNKTE
1360 1370 1380 1390 1400
CFALINANYT EVRWKNVKIN FDNVGAGYLA LLQVATFKGW MDIMYAAVDS
1410 1420 1430 1440 1450
RKVEDQPLYE DNIYMYIYFV IFIIFGSFFT LNLFIGVIID NFNQQKKKFG
1460 1470 1480 1490 1500
GQDIFMTEEQ KKYYNAMKKL GSKKPQKPIP RPLNKIQGMV FDFVTQQAFD
1510 1520 1530 1540 1550
ISIMMLICLN MVTMMVETDD QSDETENILY WINFVFIVAF TGEFVLKLFA
1560 1570 1580 1590 1600
LRHYYFTNGW NVFDCVVVIL SIVGMFLADL IEKYFVSPTL FRVIRLARIG
1610 1620 1630 1640 1650
RILRLIKGAK GIRTLLFALM MSLPALFNIG LLLFLVMFIF SIFGMSNFAY
1660 1670 1680 1690 1700
VKREIGIDDM YNFETFGNSM ICLFMITTSA GWDGLLAPIL NYPPDCDPNK
1710 1720 1730 1740 1750
ENPGTTVKGN CGNPSVGIFF FVMYIIVSFL IVVNMYIAII LENFSVATEE
1760 1770 1780 1790 1800
SADPLCEDDF ESFYEIWEKF DPDASQFITF AKLPDFADTL EHPLRVPKPN
1810 1820 1830 1840 1850
IIELIAMDLP MVSGDRIHCL DILFAFTKRV LGDSGDLDMM RQQMEERFVA
1860 1870 1880 1890 1900
ANPSKVSYEP ITTTLRRKQE EVSAIVIQRS YRSHLASRGF ICKRRPANNK
1910 1920 1930 1940 1950
LENGGGNQEK KEGTPSTASL PSYDSVTKPE KEKQDDNNEG KGRKEKGRNQ

KDVRESKC
Length:1,958
Mass (Da):222,523
Last modified:May 3, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i357E44F59C53A045
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8RXU0A0A2R8RXU0_DANRE
Sodium channel, voltage-gated, type...
scn8ab
658Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8QDT5A0A2R8QDT5_DANRE
Sodium channel, voltage-gated, type...
scn8ab
285Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Q1J5A0A2R8Q1J5_DANRE
Sodium channel, voltage-gated, type...
scn8ab
320Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Q980A0A2R8Q980_DANRE
Sodium channel, voltage-gated, type...
scn8ab
254Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Q8B3A0A2R8Q8B3_DANRE
Sodium channel, voltage-gated, type...
scn8ab
109Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Q7W8A0A2R8Q7W8_DANRE
Sodium channel, voltage-gated, type...
scn8ab
106Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CR388364 Genomic DNA No translation available.
CR753817 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000022761; ENSDARP00000013108; ENSDARG00000018032
ENSDART00000151299; ENSDARP00000126281; ENSDARG00000018032

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR388364 Genomic DNA No translation available.
CR753817 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000126281

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000022761; ENSDARP00000013108; ENSDARG00000018032
ENSDART00000151299; ENSDARP00000126281; ENSDARG00000018032

Organism-specific databases

ZFINiZDB-GENE-060906-2 scn8ab

Phylogenomic databases

eggNOGiKOG2301 Eukaryota
ENOG410XNP6 LUCA
GeneTreeiENSGT00940000156263
OMAiSIMMLIC
TreeFamiTF323985

Gene expression databases

BgeeiENSDARG00000018032 Expressed in 11 organ(s), highest expression level in brain

Family and domain databases

Gene3Di1.20.120.350, 4 hits
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR008054 Na_channel_a8su
IPR001696 Na_channel_asu
IPR010526 Na_trans_assoc
IPR024583 Na_trans_cytopl
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF00520 Ion_trans, 4 hits
PF06512 Na_trans_assoc, 1 hit
PF11933 Na_trans_cytopl, 1 hit
PRINTSiPR00170 NACHANNEL
PR01667 NACHANNEL8

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1RE76_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F1RE76
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: June 5, 2019
This is version 61 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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