Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

DEAD (Asp-Glu-Ala-Asp) box helicase 3b

Gene

ddx3xb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • brain development Source: ZFIN
  • chromosome segregation Source: GO_Central
  • regulation of gene expression Source: GO_Central
  • RNA secondary structure unwinding Source: GO_Central
  • translational initiation Source: GO_Central

Keywordsi

Molecular functionHelicaseUniRule annotation, Hydrolase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Submitted name:
DEAD (Asp-Glu-Ala-Asp) box helicase 3bImported
Gene namesi
Name:ddx3xbImported
Synonyms:ddx3bImported, pl10Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 6

Organism-specific databases

ZFINiZDB-GENE-980526-150 ddx3xb

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF1RCB2
PRIDEiF1RCB2

Expressioni

Gene expression databases

BgeeiENSDARG00000005774 Expressed in 30 organ(s), highest expression level in gastrula
ExpressionAtlasiF1RCB2 baseline

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000092924

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini208 – 236Q_MOTIFInterPro annotationAdd BLAST29
Domaini239 – 435Helicase ATP-bindingInterPro annotationAdd BLAST197
Domaini446 – 607Helicase C-terminalInterPro annotationAdd BLAST162

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi208 – 236Q motifPROSITE-ProRule annotationAdd BLAST29

Sequence similaritiesi

Belongs to the DEAD box helicase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0335 Eukaryota
ENOG410XNTI LUCA
GeneTreeiENSGT00900000140933
InParanoidiF1RCB2
OrthoDBiEOG091G04U3
TreeFamiTF300364

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

F1RCB2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHVAVENVH GLDQQLAALD LSSADVQGVT GRRYIPPHLR NKEAAKNDAP
60 70 80 90 100
GGWDNGRSNG FVNGYHDGRD NRMNGGSSFA GRGPIRSDRG GRGGFRGFGY
110 120 130 140 150
DNKEAGGWNV PKDNAYNSFG GRSDRGKSSF FNDRGSSSRG RYERGGFGGG
160 170 180 190 200
GNSRWVEECR DEDWSKPLPP NERLEHELFS GSNTGINFEK YDDIPVEATG
210 220 230 240 250
HNGPQPIDRF HDLEMGEIIM GNINLSRYTR PTPVQKHAIP IIKSKRDLMA
260 270 280 290 300
CAQTGSGKTA AFLLPVLSQI YTDGPGEALQ AAKNSAQENG KYGRRKQYPI
310 320 330 340 350
SLVLAPTREL ALQIYDEARK FSYRSHVRPC VVYGGADIGQ QIRDLERGCH
360 370 380 390 400
LLVATPGRLV DMMERGKIGL DYCNYLVLDE ADRMLDMGFE PQIRRIVEQD
410 420 430 440 450
TMPPKGLRQT MMFSATFPKE IQILARDFLE DYIFLAVGRV GSTSENITQK
460 470 480 490 500
VVWVEENDKR SFLLDLLNAT GKDSLTLVFV ETKKGADALE DFLYREGYAC
510 520 530 540 550
TSIHGDRSQR DREEALHQFR SGRCPILVAT AVAARGLDIS NVKHVINFDL
560 570 580 590 600
PSDIEEYVHR IGRTGRVGNL GLATSFFNDK NGNITKDLLD ILVEAKQEVP
610 620 630 640 650
SWLESLAYEH QHKSSSRGRS KRFSGGFGAR DYRQNSSSGG GGFGGRGGRS
660 670 680
TGGHGGNRGF GGGKGGFGNF YSSDGYGGNY SQVDWWGN
Length:688
Mass (Da):75,832
Last modified:May 3, 2011 - v1
Checksum:iEA96813915EFBBC8
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
X1WFB0X1WFB0_DANRE
DEAD (Asp-Glu-Ala-Asp) box helicase...
ddx3xb ddx3b, pl10
296Annotation score:
X1WHB2X1WHB2_DANRE
DEAD (Asp-Glu-Ala-Asp) box helicase...
ddx3xb ddx3b, pl10
228Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU855795 Genomic DNA No translation available.
CU914788 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000102148; ENSDARP00000092924; ENSDARG00000005774

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU855795 Genomic DNA No translation available.
CU914788 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000092924

Proteomic databases

PaxDbiF1RCB2
PRIDEiF1RCB2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000102148; ENSDARP00000092924; ENSDARG00000005774

Organism-specific databases

ZFINiZDB-GENE-980526-150 ddx3xb

Phylogenomic databases

eggNOGiKOG0335 Eukaryota
ENOG410XNTI LUCA
GeneTreeiENSGT00900000140933
InParanoidiF1RCB2
OrthoDBiEOG091G04U3
TreeFamiTF300364

Enzyme and pathway databases

ReactomeiR-DRE-6798695 Neutrophil degranulation

Gene expression databases

BgeeiENSDARG00000005774 Expressed in 30 organ(s), highest expression level in gastrula
ExpressionAtlasiF1RCB2 baseline

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR000629 RNA-helicase_DEAD-box_CS
IPR014014 RNA_helicase_DEAD_Q_motif
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF00271 Helicase_C, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00039 DEAD_ATP_HELICASE, 1 hit
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit
PS51195 Q_MOTIF, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF1RCB2_DANRE
AccessioniPrimary (citable) accession number: F1RCB2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: September 12, 2018
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again