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UniProtKB - F1RAF7 (F1RAF7_DANRE)
Protein
Submitted name:
Si:ch211-13k12.2
Gene
si:ch211-13k12.2
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- anatomical structure development Source: UniProt
- positive regulation of transcription elongation from RNA polymerase II promoter Source: GO_Central
- snRNA transcription by RNA polymerase II Source: GO_Central
- transcription elongation from RNA polymerase II promoter Source: InterPro
Keywordsi
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Si:ch211-13k12.2 |
Gene namesi | Name:si:ch211-13k12.2Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-061207-5, si:ch211-13k12.2 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- transcription elongation factor complex Source: GO_Central
Other locations
- euchromatin Source: GO_Central
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSDARG00000038121, Expressed in retina and 25 other tissues |
ExpressionAtlasi | F1RAF7, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 283 | ELLInterPro annotationAdd BLAST | 278 | |
Domaini | 487 – 588 | Occludin_ELLInterPro annotationAdd BLAST | 102 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 154 – 194 | DisorderedSequence analysisAdd BLAST | 41 | |
Regioni | 286 – 378 | DisorderedSequence analysisAdd BLAST | 93 | |
Regioni | 390 – 478 | DisorderedSequence analysisAdd BLAST | 89 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 169 – 190 | Polar residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 286 – 320 | Polar residuesSequence analysisAdd BLAST | 35 | |
Compositional biasi | 339 – 378 | Polar residuesSequence analysisAdd BLAST | 40 | |
Compositional biasi | 440 – 464 | Basic and acidic residuesSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
Belongs to the ELL/occludin family.ARBA annotation
Phylogenomic databases
eggNOGi | KOG4796, Eukaryota |
GeneTreei | ENSGT00940000164943 |
HOGENOMi | CLU_021268_0_0_1 |
InParanoidi | F1RAF7 |
OMAi | QPVICFK |
OrthoDBi | 335949at2759 |
PhylomeDBi | F1RAF7 |
TreeFami | TF326161 |
Family and domain databases
Gene3Di | 1.10.10.2670, 1 hit |
InterProi | View protein in InterPro IPR042065, E3_ELL-like IPR031176, ELL/occludin IPR019464, ELL_N IPR010844, Occludin_ELL IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR23288, PTHR23288, 1 hit |
Pfami | View protein in Pfam PF10390, ELL, 1 hit PF07303, Occludin_ELL, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
F1RAF7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAALRQEHRY GLSCGKINKS IPNKTIFHVK LTDTAIRTLE AYQNLKGSLP
60 70 80 90 100
NQPAICFKGN QGYIKIPASS DSPDAFRVFS FYLSSDSKDK PQASFDCVHQ
110 120 130 140 150
FVSGDGRDRL EGQGSIQDKI TVCATDDSYQ MTRERMSQVE KDIWSRSAIE
160 170 180 190 200
IKPGSTRPSK CVKIKKKQSL SASFDSTNKH SPSNKRNGGP SLVTHRPLRE
210 220 230 240 250
RVIHILALKP YSKPELLLWL EREKASPKDK ADLSPVLDEV AKLNPKEHSF
260 270 280 290 300
TLKDDFYRHV RKDWPGYVEE ERQLIQRVLA RKLQPLSSSS SSSQLKSFQS
310 320 330 340 350
SHSFHKTSGD SPSQLSPVKT PSMKRPVPSD HPESQTPKKQ RLLEQNIPLQ
360 370 380 390 400
SPSNGHLSSS VGRSSSSHGN TSLQRGPNTD EFYQRHKLNE GNSLPKTEQP
410 420 430 440 450
EPAASSPHKH PRTEPEICTD QQLANGQHKK KKSKKHKEKE RERLKPEWVE
460 470 480 490 500
TSPDLKHNQE NINDHERPNT PVTRASPDQL PDYLLKYNTI TDSEQRQRYK
510 520 530 540 550
EDFCAEYDEY RDLHERIGKV TEIFVQLGSK IKTLSPGTQE YKVMEDQIME
560 570 580 590
KYKKYKKKFP GYREEKKRCE YLHQKLSHIK GLILDYDQTQ LPS
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A2R8RHU4 | A0A2R8RHU4_DANRE | Si:ch211-13k12.2 | si:ch211-13k12.2 | 577 | Annotation score: | ||
A2BI99 | A2BI99_DANRE | Si:ch211-13k12.2 | si:ch211-13k12.2 | 307 | Annotation score: | ||
F1Q7A8 | F1Q7A8_DANRE | Si:ch211-13k12.2 | si:ch211-13k12.2 | 187 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX897658 Genomic DNA No translation available. CT025855 Genomic DNA No translation available. |
RefSeqi | XP_694180.3, XM_689088.6 |
Genome annotation databases
Ensembli | ENSDART00000099511.4; ENSDARP00000090285.2; ENSDARG00000038121.8 |
GeneIDi | 565819 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX897658 Genomic DNA No translation available. CT025855 Genomic DNA No translation available. |
RefSeqi | XP_694180.3, XM_689088.6 |
3D structure databases
AlphaFoldDBi | F1RAF7 |
SMRi | F1RAF7 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000090285 |
Proteomic databases
PaxDbi | F1RAF7 |
Genome annotation databases
Ensembli | ENSDART00000099511.4; ENSDARP00000090285.2; ENSDARG00000038121.8 |
GeneIDi | 565819 |
Organism-specific databases
ZFINi | ZDB-GENE-061207-5, si:ch211-13k12.2 |
Phylogenomic databases
eggNOGi | KOG4796, Eukaryota |
GeneTreei | ENSGT00940000164943 |
HOGENOMi | CLU_021268_0_0_1 |
InParanoidi | F1RAF7 |
OMAi | QPVICFK |
OrthoDBi | 335949at2759 |
PhylomeDBi | F1RAF7 |
TreeFami | TF326161 |
Gene expression databases
Bgeei | ENSDARG00000038121, Expressed in retina and 25 other tissues |
ExpressionAtlasi | F1RAF7, baseline |
Family and domain databases
Gene3Di | 1.10.10.2670, 1 hit |
InterProi | View protein in InterPro IPR042065, E3_ELL-like IPR031176, ELL/occludin IPR019464, ELL_N IPR010844, Occludin_ELL IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR23288, PTHR23288, 1 hit |
Pfami | View protein in Pfam PF10390, ELL, 1 hit PF07303, Occludin_ELL, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | F1RAF7_DANRE | |
Accessioni | F1RAF7Primary (citable) accession number: F1RAF7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | May 3, 2011 | |
Last modified: | May 25, 2022 | |
This is version 57 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |