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Protein
Submitted name:

Serine/threonine kinase 24b (STE20 homolog, yeast)

Gene

stk24b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • protein serine/threonine kinase activity Source: GO_Central

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-111465 Apoptotic cleavage of cellular proteins
R-DRE-75153 Apoptotic execution phase

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/threonine kinase 24b (STE20 homolog, yeast)Imported
Gene namesi
Name:stk24bImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 6

Organism-specific databases

ZFINiZDB-GENE-040426-2841 stk24b

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiF1R8K2

Expressioni

Gene expression databases

BgeeiENSDARG00000023878 Expressed in 31 organ(s), highest expression level in multi-cellular organism
ExpressionAtlasiF1R8K2 baseline

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000084749

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 262Protein kinaseInterPro annotationAdd BLAST251

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili38 – 65Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0201 Eukaryota
ENOG410XP9G LUCA
GeneTreeiENSGT00930000150827
InParanoidiF1R8K2
TreeFamiTF354217

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

F1R8K2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENLKADPEE LFTKLERIGK GSFGEVFKGI DNRTQKVVAI KIIDLEEAED
60 70 80 90 100
EIEDIQQEIT VLSQCDSPFV TKYYGSYLKD TKLWIIMEYL GGGSALDLLE
110 120 130 140 150
PGSLDETQIA TILREILKGL EYLHSEKKIH RDIKAANVLL SEQGEVKLAD
160 170 180 190 200
FGVAGQLTDT QIKRNTFVGT PFWMAPEVIK QSAYDSKADI WSLGITAIEL
210 220 230 240 250
AKGEPPHSDL HPMKVLFLIP KNNPPTLEGN YCKPLKEFVE ACLNKEPSFR
260 270 280 290 300
PTAKELLKHK LIVRFAKKTS YLTELIDKYK RWKAEQSRAE SSSDESDSEP
310 320 330 340 350
DGQASGGNDF GNDDWIFTIR EKDPKKLQNG ASLVGEEEPN KRPLSQSLST
360 370 380 390 400
VITPVLTELK EGAGEAAAAT TVKPEVLEQL GEAIFLAEEA YPGISDVMVT
410 420
QLIQRLQRFS RARTSSSSHQ
Length:420
Mass (Da):46,862
Last modified:May 3, 2011 - v1
Checksum:iD3F4731991679422
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R4IN78A0A0R4IN78_DANRE
Serine/threonine kinase 24b (STE20 ...
stk24b
432Annotation score:
F8W392F8W392_DANRE
Serine/threonine kinase 24b (STE20 ...
stk24b
260Annotation score:
F8W637F8W637_DANRE
Serine/threonine kinase 24b (STE20 ...
stk24b
180Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950176 Genomic DNA No translation available.
CR376780 Genomic DNA No translation available.
CR854986 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSDART00000090316; ENSDARP00000084749; ENSDARG00000023878

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX950176 Genomic DNA No translation available.
CR376780 Genomic DNA No translation available.
CR854986 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000084749

Proteomic databases

PaxDbiF1R8K2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000090316; ENSDARP00000084749; ENSDARG00000023878

Organism-specific databases

ZFINiZDB-GENE-040426-2841 stk24b

Phylogenomic databases

eggNOGiKOG0201 Eukaryota
ENOG410XP9G LUCA
GeneTreeiENSGT00930000150827
InParanoidiF1R8K2
TreeFamiTF354217

Enzyme and pathway databases

ReactomeiR-DRE-111465 Apoptotic cleavage of cellular proteins
R-DRE-75153 Apoptotic execution phase

Gene expression databases

BgeeiENSDARG00000023878 Expressed in 31 organ(s), highest expression level in multi-cellular organism
ExpressionAtlasiF1R8K2 baseline

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF1R8K2_DANRE
AccessioniPrimary (citable) accession number: F1R8K2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 3, 2011
Last sequence update: May 3, 2011
Last modified: November 7, 2018
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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