UniProtKB - F1R7R6 (F1R7R6_DANRE)
Protein
Submitted name:
Potassium voltage-gated channel, subfamily F, member 1b
Gene
kcnf1b
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- voltage-gated potassium channel activity Source: GO_Central
GO - Biological processi
- potassium ion transmembrane transport Source: GO_Central
- protein homooligomerization Source: InterPro
- regulation of ion transmembrane transport Source: UniProtKB-KW
Keywordsi
Molecular function | Ion channel, Potassium channelARBA annotation, Voltage-gated channelARBA annotation |
Biological process | Ion transport, Potassium transport, Transport |
Ligand | Potassium |
Enzyme and pathway databases
Reactomei | R-DRE-1296072, Voltage gated Potassium channels |
Names & Taxonomyi
Protein namesi | Submitted name: Potassium voltage-gated channel, subfamily F, member 1bImported |
Gene namesi | Name:kcnf1bImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-090312-39, kcnf1b |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- voltage-gated potassium channel complex Source: GO_Central
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 167 – 192 | HelicalSequence analysisAdd BLAST | 26 | |
Transmembranei | 242 – 267 | HelicalSequence analysisAdd BLAST | 26 | |
Transmembranei | 312 – 333 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 345 – 364 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 376 – 394 | HelicalSequence analysisAdd BLAST | 19 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSDARG00000027285, Expressed in brain and 5 other tissues |
ExpressionAtlasi | F1R7R6, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 13 – 114 | BTB_2InterPro annotationAdd BLAST | 102 | |
Domaini | 170 – 401 | Ion_transInterPro annotationAdd BLAST | 232 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 119 – 139 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 403 – 423 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG3713, Eukaryota |
GeneTreei | ENSGT00940000160213 |
InParanoidi | F1R7R6 |
OrthoDBi | 818306at2759 |
TreeFami | TF313103 |
Family and domain databases
Gene3Di | 1.20.120.350, 1 hit |
InterProi | View protein in InterPro IPR005821, Ion_trans_dom IPR003968, K_chnl_volt-dep_Kv IPR003971, K_chnl_volt-dep_Kv9 IPR011333, SKP1/BTB/POZ_sf IPR003131, T1-type_BTB IPR028325, VG_K_chnl IPR027359, Volt_channel_dom_sf |
PANTHERi | PTHR11537, PTHR11537, 1 hit |
Pfami | View protein in Pfam PF02214, BTB_2, 1 hit PF00520, Ion_trans, 1 hit |
PRINTSi | PR01494, KV9CHANNEL PR01491, KVCHANNEL |
SUPFAMi | SSF54695, SSF54695, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F1R7R6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MWTLPRTRDE KEIAVNIGGV RLVLCGDILN RYPDSRLAEL VNCPTRSFDV
60 70 80 90 100
ISSLCDDYDP GKREFYFDRD PDSFKCIVEV YYFGEVHMKR GICPICFIKE
110 120 130 140 150
MEFWKIDLSY LDECCKSNLT EKEEELAEIA DKVKLILDDL ECDPAVSRTE
160 170 180 190 200
RWQKFVWKLM EKPESSLPAR VIAVVSFLFI LISSVVMCLG TLPDLQVEDS
210 220 230 240 250
EGNRVEHPSL DAIETACIGW FTVEYVLRLA SSPNKLRFAL SFMNMIDFLA
260 270 280 290 300
VLPFYVVLVL TCLGTAMMEL VNVQQAVQAL RIMRIARIFK LARHSSGLQT
310 320 330 340 350
LTYALKRSFK ELGLLLMYMG VGIFVFSALG YTMEQSHPET LFRSIPQSFW
360 370 380 390 400
WAIITMTTVG YGDIYPKTTL GRCNAAISFL CGVIAIALPI HPIINNFVIY
410 420 430 440 450
YNKQKVLETA AKHELELMEL RALELTVRSA MRASRSDTFI PLLSGAHRTE
460
REPLKKKSLT
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF1RAI2 | F1RAI2_DANRE | Potassium voltage-gated channel, su... | kcnf1b | 455 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX470227 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000037740; ENSDARP00000034538; ENSDARG00000027285 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX470227 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000034538 |
Proteomic databases
PaxDbi | F1R7R6 |
Genome annotation databases
Ensembli | ENSDART00000037740; ENSDARP00000034538; ENSDARG00000027285 |
Organism-specific databases
ZFINi | ZDB-GENE-090312-39, kcnf1b |
Phylogenomic databases
eggNOGi | KOG3713, Eukaryota |
GeneTreei | ENSGT00940000160213 |
InParanoidi | F1R7R6 |
OrthoDBi | 818306at2759 |
TreeFami | TF313103 |
Enzyme and pathway databases
Reactomei | R-DRE-1296072, Voltage gated Potassium channels |
Gene expression databases
Bgeei | ENSDARG00000027285, Expressed in brain and 5 other tissues |
ExpressionAtlasi | F1R7R6, baseline |
Family and domain databases
Gene3Di | 1.20.120.350, 1 hit |
InterProi | View protein in InterPro IPR005821, Ion_trans_dom IPR003968, K_chnl_volt-dep_Kv IPR003971, K_chnl_volt-dep_Kv9 IPR011333, SKP1/BTB/POZ_sf IPR003131, T1-type_BTB IPR028325, VG_K_chnl IPR027359, Volt_channel_dom_sf |
PANTHERi | PTHR11537, PTHR11537, 1 hit |
Pfami | View protein in Pfam PF02214, BTB_2, 1 hit PF00520, Ion_trans, 1 hit |
PRINTSi | PR01494, KV9CHANNEL PR01491, KVCHANNEL |
SUPFAMi | SSF54695, SSF54695, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F1R7R6_DANRE | |
Accessioni | F1R7R6Primary (citable) accession number: F1R7R6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | June 20, 2018 | |
Last modified: | October 7, 2020 | |
This is version 75 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |