UniProtKB - F1QZ85 (F1QZ85_DANRE)
Protein
Submitted name:
Prolactin 2
Gene
prl2
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- hormone activity Source: GO_Central
GO - Biological processi
- positive regulation of receptor signaling pathway via JAK-STAT Source: GO_Central
- response to nutrient levels Source: GO_Central
Keywordsi
Molecular function | HormoneUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Prolactin 2Imported |
Gene namesi | Name:prl2Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-041210-160, prl2 |
Subcellular locationi
Extracellular region or secreted
- Secreted UniRule annotationARBA annotation
Extracellular region or secreted
- extracellular space Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 37 | Sequence analysisAdd BLAST | 37 | |
ChainiPRO_5003270429 | 38 – 237 | Sequence analysisAdd BLAST | 200 |
Proteomic databases
PaxDbi | F1QZ85 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000018744, Expressed in brain and 5 other tissues |
Interactioni
GO - Molecular functioni
- hormone activity Source: GO_Central
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000114109 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | ENOG502QYU3, Eukaryota |
GeneTreei | ENSGT00950000182818 |
HOGENOMi | CLU_088274_0_1_1 |
InParanoidi | F1QZ85 |
OMAi | LKLLVAW |
TreeFami | TF332592 |
Family and domain databases
InterProi | View protein in InterPro IPR009079, 4_helix_cytokine-like_core IPR001400, Somatotropin/Prolactin IPR018116, Somatotropin_CS |
PANTHERi | PTHR11417, PTHR11417, 1 hit |
Pfami | View protein in Pfam PF00103, Hormone_1, 1 hit |
PRINTSi | PR00836, SOMATOTROPIN |
SUPFAMi | SSF47266, SSF47266, 1 hit |
PROSITEi | View protein in PROSITE PS00266, SOMATOTROPIN_1, 1 hit PS00338, SOMATOTROPIN_2, 1 hit |
i Sequence
Sequence statusi: Fragment.
F1QZ85-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
XHNLSFSSPL RMSRSLKQVA VLLVALLCLD PHGRVGSAPI CAHGPSGCHV
60 70 80 90 100
PSLADLFDRV IQHSARMHSL SNDLHSEFEQ YFLPSKNHIG KIYRKCHTSS
110 120 130 140 150
ILTPNGKENA QKLAREELTE VILKLLLAWR DPLFQLHQSM AHQQDFNSFS
160 170 180 190 200
SNKALEMGDM AHELRKGVEK VAEKMRVLGM LGNSVTGLSA AEAMLPISDS
210 220 230
GEAMSDYDLL YCFRRDSNKV QNYLKILKCR IVPEHDC
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX571705 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000142845; ENSDARP00000114109; ENSDARG00000018744 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX571705 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000114109 |
Proteomic databases
PaxDbi | F1QZ85 |
Genome annotation databases
Ensembli | ENSDART00000142845; ENSDARP00000114109; ENSDARG00000018744 |
Organism-specific databases
ZFINi | ZDB-GENE-041210-160, prl2 |
Phylogenomic databases
eggNOGi | ENOG502QYU3, Eukaryota |
GeneTreei | ENSGT00950000182818 |
HOGENOMi | CLU_088274_0_1_1 |
InParanoidi | F1QZ85 |
OMAi | LKLLVAW |
TreeFami | TF332592 |
Gene expression databases
Bgeei | ENSDARG00000018744, Expressed in brain and 5 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR009079, 4_helix_cytokine-like_core IPR001400, Somatotropin/Prolactin IPR018116, Somatotropin_CS |
PANTHERi | PTHR11417, PTHR11417, 1 hit |
Pfami | View protein in Pfam PF00103, Hormone_1, 1 hit |
PRINTSi | PR00836, SOMATOTROPIN |
SUPFAMi | SSF47266, SSF47266, 1 hit |
PROSITEi | View protein in PROSITE PS00266, SOMATOTROPIN_1, 1 hit PS00338, SOMATOTROPIN_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F1QZ85_DANRE | |
Accessioni | F1QZ85Primary (citable) accession number: F1QZ85 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 3, 2011 |
Last sequence update: | January 9, 2013 | |
Last modified: | April 7, 2021 | |
This is version 56 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |